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Growth Hormone, Growth Factors IGF1-LR3, and GHRPs & GHRH

Sep 23, 2015 - 4:47 PM - by Pushtoday
The Synergistic effects of cycling HGH, IGF1-LR3, GHRPs & GHRH peptides and Growth Factors

With peptides being all the rage, and the quality and pricing improving so much more and more fitness enthusiasts and bodybuilders are looking at peptides as a possible replacement for HGH and IGF.
The question is can they replace them?As powerfull as peptides are, they are limited in the amount of IGF they can produce, And when i say peptides i mean GHRP’s and GHRH.

Subjects can mega dose them, and sky rocket IGF.. but the levels are no where near as superphysiological as direct administration over a period of time of IGF-1-lr3, the reason being is like taking a caffeine supplement, or drinking coffee, you will get more caffeine from it itself than the coffee providing in comparison a small amount.
The same is with HGH, even thought generic HGH is just one form of GH and there are many, its affects on glycogensis, stimulating satellite muscle cells into maturity and recovery, both of muscle, bone and tendons is far stronger than triggering your own GH release.. But i emphasize that peptides are very important as we have outlined before and they have a role in reaching your subjects goals.
A combination of the 2 = mass effect
When HGH and igf are combined the potential for growth is increased exponentially.. Lets say HGH = 1 and IGF = 1 the combination of the 2 would yield a number far greater than the sum of both parts, so lets say for arguments sake 1 + 1 = 5 in this case.
Combining the 2 works in synergy if the timing is right, offering the increased fat loss of HGH and even though its not been proven that elevated igf levels increases fat loss, it makes sense to conclude it does, with igf leeching glucose, your body starts relying on fat for fuel, and HGH elevates IGF, then add in an external variant of IGF and bamm, Superphisiological levels of igf. And depending on the amount of HGH you use, your flooding your sugjects body with 2 of the most anabolic hormones utilized by the subjects body.

Now lets tweak things a little..
We add in a GHRH that stimulates even more IGF.. but we dont want to do this for more than say, 30 days to prevent IGF receptors becoming tired and less recipient of circulating igf.
Then we add in a peptide like GHRP-6, 3 times a day, combining doses with your HGH… HGH should be broken up into 3 or 4 doses a day, many vets in the sport will tell you that the rewards from HGH are amplified following this method.

Your stimulating your subjects own GH pulse as and when it should normally pulse, Also increasing the amount of HGH your receptors can uptake, thus vastly improving your synthetic gh, and the increased igf from say a peptide that bleeds like cjc-1295 dac can offer huge advantages in this environment… offering cellular turn over on a level you wont have experienced.
GHRH = 1 + GHRP =1 = 3

So if HGH + IGF = 5 and GHRH + GHRP= 3 when you combine them you dont get 8 you get 10 in terms of effects.

Can you imagine what super elevated levels of IGF a hormone that initiates intracellular signaling it is one of the most potent natural activators of the AKT signaling pathway a stimulator of cell growth and proliferation, and a potent inhibitor of programmed cell death.
Now combine that with super elevated levels of HGH increases lean body mass, shortens recovery time between workouts, and enhances overall performance with less risk of detection than other performance-enhancing drugs. HGH strengthens tissues, skeletal muscle… HGH actually unlock new growth!!
After finishing puberty normally the number of muscle cells your subject has for the rest of its life is genetic, and the most you can do is increase the size of these cells through weight training or steroids. However, by using HGH, your subject can actually grow new muscle cells. This allows your subject to reverse genetic dispositions and achieve a far more striated and dense look.

You are far more likely to achieve the look your subject after, and in a lot less time but combing the best peptides with the anabolic hormones IGF and HGH.. I advise not running high doses for long periods as permanent organ enlargement is a distinct possibility, and its unlikely to be the organ your subject would choose to have enlarged.
  0 Replies | 259 Views

Beginners Steroid Cycle with Injecatble and Orals Stacked.

Sep 23, 2015 - 9:04 AM - by gandhisays
The cycle listed below is for a Beginner who has already cycled once or twice before and has had proper pct and time between cycles! Trenbolone ace or enanthate should never be used in your first cycle. Your first cycle should generally always consist of just Testosterone enanthate or cypionate at 250-500mg per week, with possibly a mild oral stacked with it such as anavar.

Is the steroid cycle below good for cutting or bulking?
No steroid is for cutting or bulking only! Some steroids are optimum for either cutting cycles or bulking cycles however it is the diet, and cardio that makes a cycle either a cutter or bulker.
Can I run dianabol, enanthate and tren ace longer than 8 weeks? The simple answer is YES of course you can run any cycle as long or short as you like. The tren ace dosages listed below are mild dosages for beginners however the synergy between the testosterone and dbol will help make the tren ace the most powerful of the 3 anabolic steroids listed in this cycle!
Weeks Dianabol
Jump Start Cycle
Trenbolone Acetate

1 50mgs per day 250mg 50mg every other day

2 50mgs per day 250mg 50mg every other day

3 50mgs per day 250mg 50mg every other day

4 50mgs per day 250mg 50mg every other day

250mg 50mg every other day

250mg 50mg every other day

250mg 50mg every other day

250mg 50mg every other day

Do I need PCT and when do I start Nolvadex and Clomid?

Yes you will always want to run post cycle therapy to help jump start your natural testosterone again. Nolvadex can be taken the last week this cycle listed above while the clomid should be taken 3 weeks after you last injection of testosterone enanthate or cypionate. If you have replaced the testosteornes with a shorter ester like propionate, then you can start your clomid the same time as your nolvadex aka Tamoxifen
  0 Replies | 135 Views

Are Sarms Legal MK-2866 Ostarine Blocks Testosterone actions on prostate. vs Roids

Sep 23, 2015 - 8:37 AM - by gandhisays
Ostarine is Legal and also the most powerful anabolic selective androgen receptor modulator -SARM- you can buy.

Ostarine aka “MK-2866” was originally developed with focuses on the development of small molecules that selectively modify the effects of androgen and estrogen receptors.

  • Non-steroidal androgen receptor agonist that binds to the androgen receptors with high affinity and selectivity

  • Doesn't bind the estrogen receptor and can't be converted into estrogenic metabolites

  • Shows lack of masculinizing side effects usually associated with steroidal and non-steroidal androgen use in postmenopausal women

  • Increases lean body mass, improves performance, enhances libido, decreases bone turnover (potentially resistant to metastasis)

  • Increases quality of life

  • Stimulates testosterone’s actions in bone, muscle, and the brain; and

  • Blocks testosterone’s actions in the prostate and skin

With these clinically researched benefits (these are not exaggerated whatsoever and are associated directly with the original Ostarine clinical trial), the team at Supplement Demand set out to find the best Ostarine supplements available to our readers.
How Does Ostarine Work?

Being classified as a selective androgen receptor modulator, Ostarine creates anabolic activity at selective androgen receptors (hence, the name), but not others.When compared to test-boosters and traditional anabolic steroids, SARMs are far more advantageous due to their lack of androgenic activity in non-skeletal muscle tissues.
In fact, Ostarine binds to the androgen receptor, which serves as a DNA-binding “transcript” that regulates the body’s gene expression and demonstrates osteo- (bone) and myo- (muscular) activity.
Ostarine’s selective process of binding and activating the androgen receptor (in doing so, altering the expression of our genes) helps to increase protein synthesis, which in turn, helps to significantly increase growth and rate of muscle development.
In layman’s terms, the best Ostarine supplements provide similar muscle growth benefits as steroids, but without the negative anabolic side effects that result in the growth of the prostate and secondary sexual organs.
By targeting muscle tissues almost exclusively, Ostarine and other similar SARMs yield significant potential for bodybuilders, power lifters, athletes, and fitness enthusiasts alike. Proactive benefits aside, Ostarine also shows reactive benefits in terms of treatments for a multitude of muscle-wasting diseases and hormone replacement therapy.
Best Ostarine Uses

With benefits ranging from increased muscle mass to fat loss to muscle-wasting prevention, it’s no surprise how diverse Ostarine is in its efficiencies for multiple different types of fitness regimens. Below, we dive a bit into its ability to yield results during a bulk, cut, and also body recomposition phase, for men and women.
Bulking with Ostarine

Primarily, Ostarine is used for bulking and gaining lean muscle due to it being the most anabolic of all the SARMs supplements.
Users typically experience increases in lean muscle in the range of 7-9 pounds during an 8-week cycle of 25-30mg per day. These muscle gains remained very stable in the sense that they didn’t deplete once the Ostarine cycle came to an end.
Generally, with Ostarine, the higher the daily dose, the more testosterone suppression. This suppression is nothing comparable to the suppression traditionally experienced with anabolic steroids, but regardless, we recommend running a “mini” post-cycle therapy (PCT) for any Ostarine cycle longer than 4 weeks.
An estrogen blocker, or SERM (selective estrogen receptor modulator), isn’t required during this PCT, either.
Cutting with Ostarine

For those with cutting (eating to a daily caloric deficit) experience, you’re most likely familiar with the all-too-common loss of lean muscle during a cut. And there’s nothing more discouraging than seeing all of your hard work diminish day after day.
As it relates to cutting, Ostarine’s protocol calls for the maintenance of muscle mass, all while reducing calories. Due to its anabolic effects, as a dieter, you’re able to prevent significant muscle and strength loss with the help of Ostarine’s “nutrient partitioning” effects.
A daily doses of 15-20 mg is recommended for a 6-8 week cycle when cutting, in order to avoid any minor side effects related to testosterone suppression.
Body Recomposition with Ostarine

Body recomposition is a process that requires not only a high degree of discipline, but also time, inevitably, as you’re ultimately trying to gain muscle, while simultaneously losing fat.
As mentioned above, Ostarine offers significant nutrient partitioningbenefits, which allows you to burn calories from stored body fat, not muscle. Another benefit that shines during a body recomp is the fact that Ostarine is taken orally, most often in capsule form, and is not methylated. Being non-methylated, in Ostarine’s case, allows it to be non-toxic and an effective aid in decreasing blood pressure.
A daily dose of 20-25 mg is recommended for a 6-8 week cycle, along with a highly optimized diet with at least 30% of macronutrients coming from lean protein sources.
Ostarine Half-Life

Ostarine has a half-life of 23.8 hours, which makes it perfect as a once-a-day supplement for maximum efficiency. Depending on which of our best Ostarine supplements you choose, however, you will need to take Ostarine multiple times per day (varying serving sizes per product), in order to hit the recommended daily doses for your specific fitness goals (bulk, cut, recomp, etc.)
Ostarine and Estrogen – Do you need an Estrogen Blocker?

SARMs do not aromatize, which is the body’s process of converting anabolic steroids and testosterone into estrogen, conferring all their effects to androgen receptor (AR) binding, and not the metabolic conversion to active androgens and estrogens.
If you are concerned about slight increases in estrogen, you can always take your favorite estrogen blocker as an added precaution.
Advantages of Ostarine vs. Steroids

To reiterate, we want you to fully understand the benefits of Ostarine, specifically as they relate to the substitution with traditional anabolic steroids. With that said, Ostarine:

  • Is non-methylated (non-toxic to the liver)

  • PCT isn’t necessary (some suppression may be present for cycles longer than 4 weeks at a daily dose of 25 mg)

  • Ingested orally (no more injections)

  • Anabolic effects (even at extremely low doses of 3-5 mg per day)

  • Great for bulking, cutting, body recomposition, and injury rehabilitation
  1 Reply | 148 Views

Testosterone a MUST in All Beginners Bulk Cycles. More effective with Oral Steroid

Sep 18, 2015 - 6:16 PM - by gandhisays
Whether your a Newbie To Steroid, or its your first bulking steroid cycle, Testosterone should always be your base steroid. Beginners would be better served using a long ester version of testosterone like enanthate or cypionate over propionate or sustanon which are shorter esters and should be injected every day or every other day as oppesed to the once a week injections of Test E or Test C.

Testosterone Propionate, enanthate or cypionate is one of the best bulking agents there is. So long as you are not super sensitive to estrogenic side effects, this should be your staple for mass building. Novices usually use around 500mg a week of a long acting ester. More advanced bodybuilders use upwards of 1000mg a week. The best way to do this is to find yourself some cheap multi-dose vials of a long acting test like enanthate. But I'm not "telling you to do this", ummm...this is for information purposes only...ok...hypothetically...If you use a shorter acting ester like propionate, it will be much more painful to administer and you will definitley not administer this amount. Prop at 100mg eod is more the norm for novices, 100-200mg daily for advanced. Prop usually comes 100mg/cc, two cc's in one shot of prop hurts!! You will definitely experience some welting if you try this. I do not recommend it. You will either be limping or rubbing your shoulder almost daily. This is miserable. Long acting esters like sustanon, enanthate, cypionate, etc. do not cause this extrem discomfort. Please keep this in mind.

Okay, so we have an oral, either dianabol or anadrol, with an injectible testosterone, and now you need a even blood level anabolic like deca or equipoise. Either one will suffice. Remember though, as we've said before, combining aromatizing drugs such as anadrol testosterone esters with progestagenic drugs such as anadrol is very risky for all but those who are not susceptible to gyno. So be careful. Even if you have used androgenic drugs such as test before with no chest soreness, be careful. If you decide to do this, you will want at least one estrogen on hand for precautionary reasons.

Assuming all is well, and you choose to take this aggressive technique, you will need at least a 2mg/lb of bodyweight per week of the injectible anabolic. You could technically use primo or winstrol as well for a little less overall bloat. The dosage patterns will be different with these drugs if used for this purpose and we will talk about this in the future. For now lets assume either deca or eq. Deca at 300-400mg/week is often used by novices, 600-800mg for advanced. In all the athletes I have known, I have not seen a reason to go above 500mg when combining deca or eq with both an oral and a testosterone ester. This dose should be more than enough to get you gaining and keep your joints from aching while you push all that heavy iron (we will get into joint/ligament/tendon properties of anabolics soon).
  3 Replies | 114 Views


Sep 17, 2015 - 8:16 AM - by Presser

  4 Replies | 261 Views

Kai Greene Not Competing In The 2015 Mr. Olympia. Video Commentary from Kai Himself

Sep 15, 2015 - 12:40 PM - by Presser
Kai Greene Disallowed to Compete in 2015 Mr Olympia Bodybuilding Contest.

  5 Replies | 230 Views

New Weekly Lottery Sponsored By: Human Evolution Supplements! Play FREE Here!

Sep 11, 2015 - 8:48 AM - by Presser
Human Evolution Supplements Weekly Lottery Giveaway!

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10 Cutting and Bulking Steroid Cycles

Jul 22, 2006 - 5:00 PM - by 38532nd
There are loads of great cycles of steroids aimed at different standards of bodybuilder or looking at different outcome. I've just picked out ten great ones and given a brief description for each. Please bear in mind that sometimes there are different names for drugs depending on where you are in the world or who makes it.

Most importantly - do not even consider using steroids... [Read More]
  52 Replies | 108,313 Views

How to take HGH. Human Growth Hormone Dosages and protocol

Jan 27, 2011 - 7:58 PM - by Chris250

Basic guide to HGH doses and protocol.


Get Realistic:

Ok, so where do I start. There are so many retarded questions out there regaurding HGH use that it hurts my eyes to constantly read them. It seems that GH is the new popular thing to do. Not... [Read More]
  13 Replies | 31,840 Views

Oral and Injectable Steroid Half Lifes. Short and Long hormone esters

Apr 27, 2012 - 9:46 AM - by big n wv
Oral steroids Drug Active half-life
Anadrol / Anapolan50 (oxymetholone) 8 to 9 hours
Anavar (oxandrolone) 9 hours
Dianabol (methandrostenolone, methandienone) 4.5 to 6 hours
Methyltestosterone 4 days
Winstrol (stanozolol)
(tablets or depot taken orally) 9 hours

Depot steroids Drug Active half-life
Deca-durabolin... [Read More]
  10 Replies | 5,180 Views

Bloodwork Lab Tests and What They mean. How Do I Read My Bloodwork

Oct 05, 2012 - 1:38 PM - by Presser
LIVER LIPID PANEL— Used to determine possible risk for coronary and vascular disease. In other words, heart disease.

HDL/LDL and Total Cholesterol: High density/low density lipoprotein ratio and total circulating concentration of cholesterol. HDL is simply the "good" lipoprotein that acts as a scavenger molecule and prevents a buildup of material. LDL is the "bad" lipoprotein... [Read More]
  10 Replies | 7,171 Views

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