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Thread: Aldactone

  1. #1
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    Default Aldactone



    Aldactone

    Aldactone
    Aldactone
    ALDACTONE -

    Remark: Internationally, numerous other compounds containing the substance spironolactone are available. Due to limited space they are not listed here.

    Aldactone is a diuretic and belongs to the subgroup of potassium-sparing diuretics. Aldactone is an aldosterone antagonist. It influences the body's own hormone, aldosterone, which accelerates the excretion of potassium and reduces the excretion of sodium and water. Simplified, aldosterone regulates the endogenous water household. The higher the aldosterone level, the more water is stored in the body. The use of Aldactone results in a significant reduction in the aldosterone level so that an increased excretion of sodium and water occurs while, at the same time, potassium is reabsorbed. This also explains why Aldactone is called a potassium-sparing diuretic since it does not cause a loss of potassium like thiazides and furosemides (lasix) do. Athletes must strictly observe that during the use of Aldactone no additional potassium is taken since this would cause a life-threatening increase in the serum potassium level. Potassium-sparing diuretics have relatively low diuretic effects so that Aldactone can be called a mild diuretic. It is interesting to note that Aldactone is also an antiandrogen since it reduces the androgen level. Female athletes take advantage of this characteristic by using it to mini-mize the virilization symptoms during steroid treatment or the symptoms after treatment. For this purpose Aldactone is normally taken daily for 10 to14 days, usually in a dose of 50 mg/day. In men this could cause problems since the relationship of the andro-gen level to the estrogen level changes in favor of the latter. Thus, common side effects in men include pain in the nipples and breast swelling (gynecomastia).

    Bodybuilders use Aldactone almost exclusively during the last week before a competition. Since this causes neither a dramatic nor an immediately noticeable draining effect, it is usually taken over 5-6 days in a dosage of 2 tablets of 50 mg daily. Both male and female athletes take it. The main problems in men consist of gynecomastia and possible impo-tence. Other side effects can be low blood pressure, muscle spasms, dizziness, gastrointestinal pain, vomiting, irregular pulse rate, and fatigue.

    Aldactone by Boehringer Mannheim of Germany is often found on the black market. A package contains 50 dragees of 50 mg each and costs approx. $30 on the black market. There are currently no Aldactone fakes available.

    Substance: spironolactone
    Trade Names:
    Aldactacine 40 comp 25 mg tab.; Searle ES
    Aldactone 25, 50, 100 mg tab; Searle S, PT, FI, DK, ES, FR, CH, NL, U.S. Mexico,
    Aldactone 25, 50 mg drg.; Boehringer G, A
    Aldactacine 40 comp 25 mg tab.; Searle ES
    Aldactone 25, 50, 100 mg tab; Searle S, PT, FI, DK, ES, FR, CH, NL, U.S. Mexico,
    Aldactone 25, 50 mg drg.; Boehringer G, A
    Aldactone 100 mg cap.; Boehringer G, A
    Aldactone 100 mg tab.; Searle GR, ES
    Aldopur 5 0, 100 mg drg.; Hormosan G
    Aquareduct (o.c.) 50, 100 mg tab.; Azupharma G
    Deverol 50 mg tab.; Waldheim A
    Duraspiron 5 0, 100 mg tab.; Durachemie G
    Jenaspiron 5 0, 100 mg tab.; Jenapharm G
    Osyrol 50, 100 mg tab; Hoechst G
    Spiractone 25, 100 mg tab.; Elvipi GR
    Spiresis 25, 50, 100 mg tab.; Lkefarmos FI
    5pirldon 25, 100 mg tab.; Orion Fl
    Spirix 25, 50, 100 mg tab.; Benzon Fl, NO; Nycomed DK
    Spiroctan 25, 50 mg drg.; Boehringer CH
    Spiroctan 100 mg cap.; Boehringer CH
    Spirohexal 100 mg tab.; Hexal Pharma A
    Spirolang 25, 50, 100 mg cap.; Sit I
    Spirolone 25 mg tab.; Berk CZ
    Spiron 25, 100 mg tab.; Ercopharm DK
    Spirono-ISIS 50/100 50, 100 mg tab.; ISIS Pharma G
    Spironolacton dumex 50, 100 mg tab.; Dumex NL
    Spironolacton Heumann 50, 100 mg tab.; Heumann G
    Spironolacton mp 25, 50 mg, tab.; MP NO
    Spironolacton Stada 50, 100 mg tab.; Stadapharm G (o.c.)
    Spironolacton-- ratiopharm(o.c.) 50, 100 mg. tab.; ratiopharm G
    Spironolactone scher 50, 75 mg tab.; Scher FR
    Spironolactone (o.c.) 50, 100 mg tab.; Lederle U.S.
    Spironolactone (o.c.) 50, 100 mg tab.; Geneva U.S.
    Spironolactone (o.c.) 50, 100 mg tab.; Warner Chilcott U.S.
    Spironolactone 25 mg tab.; Mylan U.S.
    Spironolactonum gf 25, 50, 100 mg tab.; Gf NL
    Spironolactonum pharbita. 25, 50, 100 mg tab.; Pharbita NL
    Spironolakton Bota 25, 5 0, 100 mg tab.; Bota S
    Spironolakton Fermenta 50, 100 mg tab. Fermenta S
    Spironolakton NM Parma 25, 50, 100 mg tab.; NM Pharma S
    Spiro-Tablinen (o.c.) 100 mg tab.; Sanorana G
    Spiro-Tablinen- Tabletten 100 mg tab.; Wenig A
    Verospiron 25 mg tab.; Hormosan G
    Verospiron 50, 100 mg cap. Hormosan G
    Verospiron 25 mg tab.; Gedeon Richter HU, CZ





    Last edited by HackTwat; 11-27-2013 at 11:44 PM.
     

  2. #2
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    Default Spironolactone the active ingredient in Aldactone side effects, dosages, and drug interactions

    Common use in bodybuilders precontest regimen:

    Magnium and potassium-sparing diuretic and aldosterone antagonist. It competitively associates with aldosterone receptors in in the distal parts of the nephron. It has a diuretic effect, increases excretion of natrium ions and decreases excretion of potassium and magnium, decreases urinary acidity. The diuretic effect of the medicine is MODERATE at best and appears usually after 2-5 days of treatment and continues during 2-3 days after discontinuance of the medicine intake. For this reason those bodybuilders who find themseleves needing to use aldactone due to insufficient show preperation, will usually start this drug 5-6 days out from contest day. Example: if the show is on saturday, most competitors will start first dosage on Monday.



    Male and Female Bodybuilding ,Classic Bodybuilding, Mens and Womens Physique Precontest Dosage and Direction for Aldactone Use.

    Daily dosages 50-100 mg should be divided into 1-2 intakes per day. On necessity the dose maybe gradually increased up to 200 mg a day. Duration generally 5-6 days prior to contest. Consulting a physician before you decide to take this medicine is highly recommended. Aldactone should be taken after a meal after second meal and prior to going to sleep.

    Precautions

    Avoid eating salt because excess of salt may cause your body to retain water having the opposite intended effect. It is recommended not to take salt substitutes or low-sodium milk products which contain potassium.

    Contraindication

    Hypersensitivity, Addison disease, hypercaliemia, hyperpotassiemia, concomitant intake with potassium supplements or other potassium-sparing diuretics such as Aldactazide, amiloride (Midamor, Moduretic), triamterene (Dyrenium, Dyazide, Maxzide), hyponatriemia, chronic kidney failure, diabetic nephropathy, anuria, liver failure, diabetes at supposed chronic kidney failure, diabetic nephropathy.

    Side effects associated with Aldactone

    Side effects of the medicine include headache, diarrhea, cramps, drowsiness, rash, nausea, vomiting, impotence, irregular menstrual periods, and irregular hair growth. Fluid and electrolytes imbalance are likely. Enlargement of the breasts may also occur depending on dose and duration of therapy. This condition is usually reversible when you discontinue to take Aldactone.

    Drug interaction

    This medicine can lower blood sodium levels while raising blood potassium levels. Excessively high potassium levels in blood sometimes cause potentially life-threatening abnormalities in heart rhythm. Therefore, Aldactone usually is not administered with other agents that can raise blood potassium levels. Aldactone can cause elevation of blood digoxin (Lanoxin) to toxic levels.

    Missed dose

    Never take a double dose of this medication. If it is almost time of the next dose just skip the missed portion and continue to take the medicine according to the schedule.

    Overdose

    Immediate medical attention in needed in case you overdosed intake of the medicine. Overdose symptoms may include drowsiness, confusion, red skin rash, nausea, vomiting, or diarrhea.

    Storage

    Aldactone should be stored at room temperature, below 25 C (77 F).
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    Default


    Aldactone

    Aldactone

    Aldactone

    Aldactone


    Aldactone

    Aldactone
    Aldactone
    Aldactone

    Aldactone to treat acne
    Spironolactone treatment for hormonal inbalances and fluctuation induced Acne.




    Abstract

    Many cases of acne are hormonal in nature, meaning that 
they occur in adolescent girls and women and are aggravated 
by hormonal fluctuations such as those that occur during the menstrual cycle or in the setting of underlying hormonal imbalances as seen in polycystic ovary syndrome. For these patients, anti-hormonal therapy such as aldactone (spironolactone) is a valid and efficacious option.

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