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View Full Version : New Drug relased for DHT blocking



DecaDent*
01-14-2003, 12:58 PM
Dutasteride(brand name Avodart) is now avalible in the US. It is a superior 5 alpha reductase inhibitor to Finasteride(Proscar/Propecia)blocking both the type one and type two enzymes that convert Test to DHT. Type two is primarily active in the prostate while type one is also responsible for testosterone conversion in the skin and liver.
Finasteride is about 70% effective in blocking Test conversion,where Dutasteride is over 90%. Potential sides are essentially identical.
Dutasteride will give better protection against the developement of baldness and prostate problems than anything previously avalible. It comes in a 0.5mg soft gel dosed once daily.
I'm switching from Proscar to Avodart this week and let y'all know how it goes.

Team Flex
01-14-2003, 01:01 PM
Good info, Keep us informed DD!! :D

2damtight
01-14-2003, 01:29 PM
Deca can you give me an idea where to get it.

dedprez*
01-14-2003, 01:31 PM
what is the cost?

skwood
01-14-2003, 01:47 PM
Bump.

DecaDent*
01-14-2003, 02:22 PM
It's Rx only,no black market out yet that I've seen.
Scherer in France produces it for GlaxoSmithKline here in the US. The retail cost is less than Proscar.

Presser
01-14-2003, 03:41 PM
sweet

Gear101*
01-15-2003, 10:31 AM
just let it go then go to Bozley Clinic.. LOL

Badgermoon
01-15-2003, 10:36 AM
You say this is a good prostrate protector? Is that correct? If so I'll have to check with the clinic, very cool.

jake steed
01-15-2003, 11:18 AM
Wow sounds good.. Do you just go to the doc and tell him you noticed some hair loss and want it?

DecaDent*
01-15-2003, 12:34 PM
Originally posted by jake steed
Wow sounds good.. Do you just go to the doc and tell him you noticed some hair loss and want it?

That might work,although the manufacturer has not gone after the hairloss indication. You could say that you've been on Propecia and your nopt 100% satisfied and want to try Avodart,your Doc may buy that story...

The prostate indication is where the money is so thats why they've focused on that indication 1st. It's superior to Finasteride(Proscar/Propecia) on DHT blocking so for MPB it should be a superior drug as well.
Badgermoon,It blocks DHT so well there are preliminary studies looking at reduction/treatment of prostate cancer with this drug,something Finasteride has not done.

guntruck
01-15-2003, 12:41 PM
Wow this sounds wonderful, with no known online sources though gets me in the dumps I have no patience.

46and2aheadofme
01-15-2003, 05:20 PM
Price from a doc should be around $75 per 30 tabs, at least that's the cost I've heard.

fitnessbuff
01-15-2003, 06:21 PM
$$$ cha-ching$$$:(

hopkins
01-16-2003, 06:11 AM
I have been researching this drug many months before it was approved.
Go to this site
http://www.hairsite4.com/cgi-bin/dcforum/dcboard.cgi?az=list&forum=DCForumID5&conf=DCConfID3

these guys have been on the stuff since it's release and on this site you can find everything you want to know.
How to get a script, half life, side effects, effectiveness and everything else you could imagine.

I know a lot about the stuff so If anyone has any questions just post and i will be sure to answer.

lwgy
01-16-2003, 02:38 PM
is there a difference between taking Dutasteride at the 0.5 dosage versus just upping the dosage of Finasteride? it seems like it would have the same effect.

NeotonBomb
01-16-2003, 06:04 PM
I 've got an online script for avodart with a six months refill.
I'm worried about the gyno sides of dutersteride though. I've experienced gyno with propecia, so I would think the gyno sides would be worse. I've used Femara with propecia and it doesn't seem to help. Test and dutersteride should ROCK with those with the MPB(male pattern baldness).

dedprez*
01-16-2003, 06:09 PM
take an anti-e then

hopkins
01-17-2003, 07:31 AM
Dut at .5 mg is far more effective than Finasteride at even 5 mg a day.
In fact preliminary trials suggest .1 mg of Dut daily is equal to about 5 mg of finasteride ( this is of course 5 times over the propecia dose ).


The biggest flaw with Propecia is that infinate doses have no effect on type 11 5 alpha reductase and Avodart ( dutasteride ) is a much more powerful blocker anyway.

As for gyno concerns the % of incidents are almost identical to that of propecia and of course armidex 1/2 tab twice a week will combat those man boobs effectively, if the problem arises.
There are some natural estrogen supresses that many have had success with, they may be worth checking out.

Honestly though, if anyone has any concerns post on that board I gave a link to, these guys are very knowledgable and are willing to answer most questions.

NeotonBomb
01-19-2003, 06:54 AM
Hey Dead,
I'm going to go with Femara.

Stickler*
01-24-2007, 01:12 PM
some good info... curious if there are new hair loss rememdies out there... which ones seem to continue to float... the only thing i ever did was use Nizerol 2% shampoo I ordered way back when from some online source...

regardless... bump for updated info anyone might have to say

Presser
01-10-2013, 08:38 AM
Dutasteride(brand name Avodart) is now avalible in the US. It is a superior 5 alpha reductase inhibitor to Finasteride(Proscar/Propecia)blocking both the type one and type two enzymes that convert Test to DHT. Type two is primarily active in the prostate while type one is also responsible for testosterone conversion in the skin and liver.
Finasteride is about 70% effective in blocking Test conversion,where Dutasteride is over 90%. Potential sides are essentially identical.
Dutasteride will give better protection against the developement of baldness and prostate problems than anything previously avalible. It comes in a 0.5mg soft gel dosed once daily.
I'm switching from Proscar to Avodart this week and let y'all know how it goes.

Has anyone used this stuff and if so what did you think about it?

csuperman
01-11-2013, 12:59 PM
Has anyone used this stuff and if so what did you think about it?

tried it for a while but not long enought to tell if it had any effect on the hair and it's pricey compared to finesteride.