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View Full Version : Clenbuterol: Muscle Catabolism. READ!!



sasha
07-04-2001, 09:32 AM
thought this might be helpful to some over here... this brother knows his stuff... and said he will be stopping by...

Date: July 01, 2001 06:15 AM
Author: DNP guru (dnp101@elitefitness.com/montecristo412@hushmail.com)
Subject: Clenbuterol: Muscle Catabolism. READ!!


clen at high doses can be catabolic to muscle. yes, catabolic. this is due to clen's ability to increase the calcium ion channel permeability in the sarcoplasm. what does increased calcium ion channel permeability mean to you in terms of muscle catabolism? in a nutshell, it causes leakage of calpains and proteases into the muscle to break down muscle tissue. this obviously is not good.

clen is a good anabolic because of certain adrenal cortex stimulations, but this is counteracted by the release of proteases and calpains into the muscle, thus giving clen a limited anabolic effect, generally confined to the first 3-4 days of use. after that, most of its effect is on fat catabolism.

there are drugs you can take to block the release of calpains directly and also block the calcium ion channel's leakage. such blockers are amrinone and dantrolene and trental. blocking calcium ion channels can lead to extreme lethargy though and is best saved for night time use because it will help put you to sleep. a combination of calcium ion channel blockers and clen can be a powerful anabolic.

one more wrinkle to add is ketotifen which upregulates the beta 2 receptors that clen binds to. ketotifen makes these receptors so sensitive that they will NEVER downregulate while on a clen cycle as long as you are taking ketotifen. this allows for continuous doses of clen without having to cycle off to regenerate the receptors. also, ketotifen additions allows you to use less clen to get the same fat loss benefits. less clen = less side effects and also less calcium channel leakage.

sasha
07-04-2001, 09:48 AM
ok question... i have not heard of these..  are they available in the US... "such blockers are amrinone and dantrolene and trental"
also . .would you take all of them or just one with the  ketotifen and what would be the right amount to take???

sykchyk1
07-05-2001, 09:47 AM
great info. is the ketotifen only beneficial with clen, or would it also help with AS (like anavar)?

Stickler*
01-05-2007, 01:06 PM
bump for the ladies