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gearedup
03-20-2002, 07:23 PM
Diet Supplement Causes Liver Damage

Read Labels Closely for Toxic Ingredients
By Jeanie Davis


March 18, 2002 -- If you're taking a weight loss or bodybuilding supplement, listen up. Seven people in California have been treated for liver damage -- one of whom had severe liver failure -- that developed within one month after they started taking the weight loss supplement LipoKinetix.


Toxic reactions have been reported with several ingredients in LipoKinetix -- sodium usniate, yohimbine, and phenylpropanolamine (PPA). In fact, animals that have ingested lichens containing usnic acid -- a component of sodium usniate -- have become paralyzed and died.


While the FDA has forced removal of LipoKinetix from the market, products with similar ingredients are still available on the Internet.


Although no single liver toxin has been identified in LipoKinetix, the interaction of ingredients is likely causing the toxicity, says researcher Joya T. Favreau, MD, researcher at Cedars-Sinai Medical Center in Los Angeles. Her report appears in the April 16 issue of Annals of Internal Medicine.


In November 2001, the FDA issued a warning about the product, advising the distributor to take "prompt action" to remove LipoKinetix from the market.


However, the ingredients of LipoKinetix appear in other supplements marketed by the manufacturer. They also appear in products sold on bodybuilding and nutritional supplement Internet sites.


The seven patients in Favreau's report -- all otherwise healthy people between ages 20 and 32 -- were treated at Cedars-Sinai Medical Center in Los Angeles and were identified through the FDA's MedWatch program. Medwatch is the FDA's main source of reports about toxic reactions to supplements.


All had been taking LipoKinetix according to the manufacturer's recommendations. Five had been taking the supplement for one month or less. All had symptoms of acute liver damage, including fatigue and abdominal pain, and all had jaundice. All recovered spontaneously after they stopped taking LipoKinetix.


One patient developed severe liver failure with subsequent swelling in the brain. He was placed on a liver transplantation list but recovered on his own after the supplement was stopped.


"Dietary supplement products are not subject to review by the FDA before marketing," writes Favreau. The public and the medical community often are unaware when supplements contain ingredients in new combinations or dosages that may be toxic. Also, patients often don't tell their doctors that they are taking supplements.


An accompanying editorial calls for changes in laws that would mandate FDA regulation and safety surveillance of supplements.


"We require proof that prescription drugs are sufficiently safe and effective before marketing," writes James. D. Lewis, MD, of the University of Pennsylvania. "We require proof that over-the-counter drugs are extremely well studied, effective, and very safe before we permit them on the market for consumer use. Yet, there are no data for most supplements, merely because they do not claim to prevent or treat specific medical conditions."

NAPALM1
03-20-2002, 07:56 PM
Thats pretty interesting. A lot of people rave about how well Lipo works to. Later

jstrong20
03-20-2002, 10:50 PM
damn, I won't use that shit.  I'll just stick to the safe stuff like DNP.lol

NAPALM1
03-20-2002, 11:30 PM
LOL

bigjim33
03-21-2002, 12:27 PM
is that the same shiat that is in NYC?  i was thinking about using it but if it is the same stuff i might have to change my mind.

strenghtrip
03-21-2002, 05:23 PM
thanx geared

stumpy
03-21-2002, 05:45 PM
wow that's scary bro.  syntrax, the company that makes the product, i thought, was pretty good.  i tried their adipokinetix, and the shit was potent.  it was made of norephedrine.  it got me so amped that i couldnt even workout.  then i heard that lipokinetix came out and it was less speedy.  never tried it but i recommended it to my father. I FEEL LIKE SHIT NOW, THANKS.  BETTER GIVE POP A CALL I GUESS.

BStrongBwell*
12-27-2003, 08:36 PM
An oldie worth BUMPING