Intramuscular Use of HCG versus subcutaneous (subq) injections
[h=1]Injecting HCG into the muscle[/h]
Intramuscular use of HCG gets the drug into the plasma much quicker than the subcutaneous method. Also, much more of the drug is available at the action site (the leydig cells) at a given time. The advantage to this is a more potent activation of the cells if they have been suppressed to a greater extent.
Intramuscular use of HCG can also be used as a quick jump-starter to allow a faster onset of recovery and stimulation of testosteorne. This is very useful if you are a seasoned user or one of our...ummm...permanent replacement individuals before permanent replacement age. You know, from your 20's to early 30's and never seem to go off. Yeah, if thats you, you probably want to go the intramuscular route because your leydig cells have had a long, deep, nap. More like a hibernation.
"Theoretically", you could always use a large intramuscular dose of HCG to jump start the testis. Then follow up with smaller, more physiologic doses of HCG until you feel healthy and have recovery of your testosterone and testicular size.
[h=1]Injecting HCG Subcutaneous[/h]hCG is a peptide hormone similar to Growth Hormone and therefore can be administered under the skin with a small needle (subcutaneous), or in the muscle with a larger needle (intramuscular). Subcutaneous injections of drugs that can be used both under the skin and in the muscle differ in the speed of "onset of action". If you inject hCG subcutaneous, you will have a slower onset of action and it will last longer (longer half-life).
If we inject subcutaneous we create a more time-release effect and a unique event called a 'biphasic' effect. hCG is always going to differ in behavior when compared to the body's own endogenous luteinizing hormone (LH). The level of testosterone stimulation is much greater with hCG mainly due to the larger physical size and hydrophilicity of the hCG molecule compared to the smaller more soluble and shorter acting LH. Our bodies tend to release natural LH (the hormone we are mimicking with HCG) every single day in small bursts. This type of hormone is called a circadian hormone meaning that it is regulated in pulses throughout a 24hr period. If we are trying to normalize our system, it makes sense to restore it using drugs in a method which allow the must "natural"/"normal" manner to do so. unfortunately hCG although very effective at wakening the leydig cells to produce testosterone, is a bit overkill.
we have to take various ancillary drugs at specific times in order to make sure that the hCG does not become extremely unproductive by destroying the testosterone to estradiol (t:e2) ratio at a critical time. and there is no more critical time than post cycle AAS when it comes to the importance of precise T:E2 regulation. if you don't already know that hCG tends to raise estradiol as well if not better than it raises testosterone - and you have never gotten GYNO during PCR, you must be 1/8th Irish like me and have a little luck working in your favor. hCG is an estradiol beast. especially above specific threshold doses where lots and lots of studies on male hypogonadism and fertility back this up.
