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Thread: Igf-1 lr3 round 2

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    Default Igf-1 lr3 round 2



    Igf-1 lr3 round 2
    Starting my second go with igf-1 lr3. Currently running..

    Test cyp 500 mgs
    Eq 500 mgs
    Tbol 50 mgs
    Igf-1 lr3 50 mcg

    Cycle is going really well, but dealing with that annoying pain in my left shoulder that I get often. There is no way I am letting up at this point! Results are starting to come on, so I am pushing through it.

    Started yesterday by applying the igf to the hurt shoulder. Did pre-workout & noticed very little discomfort with my shoulder today. Hopefully there is much more healing to come. Also, it is a good point to start the lr3 because the results are already showing from the gear & supposedly the igf will only make that even better. My last experience with lgf-1 lr3 was at the end of the cycle & this will be mid cycle. Anxious to see what it can do at this point.
     

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    Quote Originally Posted by Big Beef View Post
    Starting my second go with igf-1 lr3. Currently running..

    Test cyp 500 mgs
    Eq 500 mgs
    Tbol 50 mgs
    Igf-1 lr3 50 mcg

    Cycle is going really well, but dealing with that annoying pain in my left shoulder that I get often. There is no way I am letting up at this point! Results are starting to come on, so I am pushing through it.

    Started yesterday by applying the igf to the hurt shoulder. Did pre-workout & noticed very little discomfort with my shoulder today. Hopefully there is much more healing to come. Also, it is a good point to start the lr3 because the results are already showing from the gear & supposedly the igf will only make that even better. My last experience with lgf-1 lr3 was at the end of the cycle & this will be mid cycle. Anxious to see what it can do at this point.
    I never ran it on cycle. I have ran it solo and with sarms. I did notice my shoulder, which has a steady issue when doing certain movements was improved eith igf1 shots to it. I also noticed my traps grew, which seemed like nothing else would make them pop the way igf1 did.

    I noticed on my current cycle of test/tren same things, shoulder is improved and traps are growing. Perhaps it is trens unrivaled ability to increase igf1?

    One day I'll combine the two. Mayve even use gh with gear as well. I have used a lot of peptides and such, but never really combined much. I like to see things solo before I combined, just how I am haha. Soon. Very soon.
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    Quote Originally Posted by guardianactual View Post
    I never ran it on cycle. I have ran it solo and with sarms. I did notice my shoulder, which has a steady issue when doing certain movements was improved eith igf1 shots to it. I also noticed my traps grew, which seemed like nothing else would make them pop the way igf1 did.

    I noticed on my current cycle of test/tren same things, shoulder is improved and traps are growing. Perhaps it is trens unrivaled ability to increase igf1?

    One day I'll combine the two. Mayve even use gh with gear as well. I have used a lot of peptides and such, but never really combined much. I like to see things solo before I combined, just how I am haha. Soon. Very soon.
    That's a good way to be bro. I didn't originally intend on starting it mid-cycle, but it just kind of happened that way because of my shoulder. I've read some reviews of guys that have done it that way & they seemed to love it.

    Gained 8 lbs in first 2 weeks of this cycle, so it is going very well. I'm assuming there will be some good benefits from throwing it in at this point, but only time will tell.
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    Igf1 from my experience and I have ran it for months back in the day. about 6 months straight from 50mcg to 200mcg a day. I may have went up to 300 cannot remember lmao. There is size but not like with aas. I read igf1 increase muscle cells and aas increase the size of the muscle cell. I know igf1 made mine arms and traps and shoulders denser. Like, I feel those who don't understand this, may see it as useless? Either that or they got some cheap bunk? Bc before using MC I was skeptical bc I saw a lot of bad reviews on peptides and some decent ones.

    I can say mc igf1 made improvements to my shoulder health as well as gave me a solid pump and vascularity and size where i put it at.

    One of the training couches at the gym told one of the big mf there he should use it before he does comp. I had not heard that before, but he was telling him how important it was in his cycle idk if he used it tho, I heard this a while back. I never competed nor had a trainer or coach so yeah, but the coaches in my city swear by it.

    Big 5 seem to be
    Test
    Tren
    HGH
    IGF1
    Synthol from what they say. You hear a lot of free shit at my gym lmao. People are pretty open about peds there.
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    6 months is quite the stretch. Sounds like it worked well for ya. Anything that can help to repair & still put some lean muscle on, is pretty much priceless
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    Quote Originally Posted by Big Beef View Post
    6 months is quite the stretch. Sounds like it worked well for ya. Anything that can help to repair & still put some lean muscle on, is pretty much priceless

    The healing effect for my shoulder was worth it alone honestly. I was going to use tb500 but never did. Igf1 worked for me. I had no issues except subq which seems to always knot up no matter what I shoot there. Could be the overuse bc I shot subq A LOT 5x a dsy at one point bc of the hgh peptides. Igf1 in AA is not fu. For me subq niggling burning sensation. Lmao i hated that.
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    Quote Originally Posted by guardianactual View Post
    The healing effect for my shoulder was worth it alone honestly. I was going to use tb500 but never did. Igf1 worked for me. I had no issues except subq which seems to always knot up no matter what I shoot there. Could be the overuse bc I shot subq A LOT 5x a dsy at one point bc of the hgh peptides. Igf1 in AA is not fu. For me subq niggling burning sensation. Lmao i hated that.
    I agree for sure. If it heals, it's worth it!

    Never done subq, but I see that a lot of guys do. Might have to give it a try some time
     

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    Quote Originally Posted by Big Beef View Post
    6 months is quite the stretch. Sounds like it worked well for ya. Anything that can help to repair & still put some lean muscle on, is pretty much priceless
    It was haha I was a rep at the time and amassed a ton of credits. I need some IGF1 now man. My elbow has been kinky. Id shoot triceps and it would clear up the kink. Did for my shoulder.

    Besides that... i wanna see what it does on Tren 😁
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    Quote Originally Posted by guardianactual View Post
    It was haha I was a rep at the time and amassed a ton of credits. I need some IGF1 now man. My elbow has been kinky. Id shoot triceps and it would clear up the kink. Did for my shoulder.

    Besides that... i wanna see what it does on Tren 😁
    I haven't done tren yet, but I definitely will in the future. I think it would make an interesting log if stacked with tren. I would follow it for sure
     

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    The igf is definitely working on me now. Last couple days my pump has increased, which it was already really nice from the gear, but is an all day thing now.

    Other than that, I am getting the sleep affect & it is nice, but I am pretty lethargic during the day. It actually seemed to hit me much harder this time than it did the first time I tried igf-1lr3. I don't know if the gear is some how intensifying the effect of it or what.. if that even makes sense. Either way I was doing around 60 mcg, than 50 mcg & I think I will drop it to 40 mcg. I think that's the dose I was at when I stopped it last time.
     

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    Thought I'd give an update before I crash for the night. Sleep still looking good, which is a huge plus for me because I usually sleep like crap. Making some other changes as well, like with my training & also not staying up all night like I usually do.

    Though my strength is increasing, I am staying disciplined & not allowing myself to go to low on reps. I feel better in with the pump I get & my shoulder was not reacting well to those heavy bench days & heavy curls. Shoulder is feeling a little better though & enjoying the even better pumps now, since adding igf.
     

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    Did chest, shoulders & tri's today. Tried a different routine. Surprising that my shoulder didn't bother me more with all 3 of those together, but it went well. Pump was unreal! Test cyp & eq have yet to REALLY kick in, so it will be interesting to see how the igf-1 lr3 does with those two.
     

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    Igf-1 lr3 round 2
    Starting to lean out. Same thing happened last time with igf. Needing to get more lean, so I am very happy about that! Sleep still continuing to get better & as I said before, this is a major plus for me! All is good... no complaints. Will keep the updates coming.

    20170802_215618.jpg

    234 lbs currently. Shooting for a lean 245-250 lb, for this cycle. Probably won't get as lean as I want, but igf helping
     

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    Very nice brutha! I attribute my lean low bf soley to igf as well
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    Quote Originally Posted by Presser View Post
    Very nice brutha! I attribute my lean low bf soley to igf as well
    It is good at leaning for sure
     

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    Since the start of the igf-1 lr3 & some changes in my routine, my shoulder is doing much better. Big relief, since it was pretty constant pain for a while now.

    Still feeling the better quality sleep & the all day pump as well
     

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    Hey Big Beef, I had shoulder issue in spring.
    Best thing I did is stopped bench press with barbell free weights. I now use Smith
    I stopped using more than 60 lb dumbbells on shoulder presses. Actually my shoulders and chest are not weak points at all in development so why kill them!!!

    Igf did alot for me but I will be honest completely. Using IGF with ipamorelin or gh releasing peptides makes it do so so so much more for me and Others.

    Or using IGF with hgh!!! Healing like I never saw. MC igf!!!
    Don't know if it's just me but after hgh release and a good one IGF does it work. Now add some MC long action lr3 to this and see. I fall asleep standing doing paperwork after gh then workout igf end burn out part of workout eat after and bam!!!! Lol!!
    Hgh opens pathway for IGF to work it clears things that interfer and opens receptors and allows it travel thru body more.
    Lr3 modification is a half life but only a resistance to proriens that stop IGF the half life is active before destroyed by body before binding. Not after binding.
    Once igf binds to receptors doesn't matter what form they all last same once bound. The don't affect u shorter or longer like a drug half life.
    Igf does nothing till bound to sites.
    Half life only applies to how long it can survive before bound before being destroyed by
    Bodies defense!!

    Hope i made sense!!!
    Did my 2.5iu hgh driving to gym have my IGF MC in lunch cooler bag with other 2.5 iu hgh pin for later.

    This way to me gets most out of igf!!!
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    Glad to hear your shoulder is doing better. Interesting too to hear how well stacking peptides worked for you & others.
     

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    Quote Originally Posted by Big Beef View Post
    Glad to hear your shoulder is doing better. Interesting too to hear how well stacking peptides worked for you & others.
    It is A FACT PROVEN, that igf use will not raise blood plasma serum levels a FACT!!!

    But use some hgh eat an hour later go do hgh and igf blood test and igf will.be raised a d hgh. This in my option proves administering IGF doesn't travel thru body!!
    Lol

    Also if insulin is present it blinds gh release natural and self administration.

    This is what somaslatin the presents of it stops. Igf does shuttle glycogen and glucose like insulin, but I believe receptors still need gh release natural or self administration of Mk 677, peptides, or hgh

    Other than that it will cause some of good affects but not all or as well!!!

    I may have repeated myself but I can honestly tell u that I know many who say same as me and only use together or just for pumping affect and some cell splitting due to site injection.

    The difference from just IGF or just hgh that u feel as compared to using both are unbelievable.

    I have some water weight from Lgd and from having surgery and coming to cruise low doing TRT bloods and bumping back up, but when this clears affects will show.

    MC igf is good I got some from a guy who didn't want it to go bad and couldn't use with hgh he is on due to this affect being stronger on him
    U wanna go hypo use it with hgh.
    Why I use at end of workout because carbs and hgh and I can't stand longer than 30 minutes of MC igf with no carbs so impossible to use pre-workout

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    Thank you for the "PROVEN FACTS" bro! Lol interesting piece of info. All I know, is that both times I have taken it, I have gotten more lean, had a better pump & slept much better. As far as scientific data go's, I can only tell ya what I've read. All the research I read suggested that lr3 traveled throughout the body for 20-30 hrs (medical sites & not sites selling lr3) as well as having insulin like properties. Guess this issue is still being debated, so let me be very clear... I don't know if It's a FACT... Only what I've READ & dealt with from personal experience!

    I also know that countless reviews on mc, as well as other sites, have had similar effects of guys using igf-1 lr3 solo & getting great benefits... solo! I just log it man. I don't debate what's a fact & what's not. Thanks again for your 2 cents!
     

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    Quote Originally Posted by Big Beef View Post
    Thank you for the "PROVEN FACTS" bro! Lol interesting piece of info. All I know, is that both times I have taken it, I have gotten more lean, had a better pump & slept much better. As far as scientific data go's, I can only tell ya what I've read. All the research I read suggested that lr3 traveled throughout the body for 20-30 hrs (medical sites & not sites selling lr3) as well as having insulin like properties. Guess this issue is still being debated, so let me be very clear... I don't know if It's a FACT... Only what I've READ & dealt with from personal experience!

    I also know that countless reviews on mc, as well as other sites, have had similar effects of guys using igf-1 lr3 solo & getting great benefits... solo! I just log it man. I don't debate what's a fact & what's not. Thanks again for your 2 cents!
    Lr3 igf can live in body for 20-30 hours without protien binding to stop it. But we want igf to attach to receptors not travel thru body.
    And if it did such a thing then why are there not plasma increases on blood test after self administration????
    Be cause it quickly binds to receptors.

    It is a fact that it only increases blood levels thru gh releasing peptides.

    Kind of like the ham wuth no burger
    I wikl post up stuff in thread. Insulin like growth factor is what th causes for release naturally thru gherilin signals from empty stomach. It starts with gherilin then signal hypothesis to signal pituartary gland to make store and release growth hormone.
    This release stops with presents of insulin. So the idea is don't eat an hour on either side of gh. Are else liver will stop manufacturing glycogen. Because glucose then insulin is available. We want hgh the igf release. I know if u carb up I get pump but that is also from insulin. IGFmay be good but hands down has no effect compared to hgh or combination.
    Igf is bound to receptors and over it doesn't travel only if manufactured in liver after gh release. Most if studies were done on hgh igf release.
    If igfalone did such thing why isn't it detectable in blood levels like after hgh release,?? I am being honest IGF not worth much to me unless hgh combined. The pathway needs to be open just like somaslatin block gh


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    Here is a thread from somewhere else...the debate is on whether the IGF effects are local or systemic. I thought it was pretty straight forward on how it all works and how one might use IGF...my interest is in using it after my rotaor cuff repair.

    !st poster - If you want to use IGF for localization growth get some rhIGF-1. It binds to the wound only and does not go into the bloodstream. This helps repair the injection wound and makes new cells in that area only. While Long R3 IGF binds somewhat to the would then makes its way to the blood stream causing growth throughout the body..

    Response - This is false.

    The difference between rhIGF-1 and Long R3 is that the Long R3 does not get bound by binding protein and thus is 100% active whereas you do lose a great % of whatever amount of rhIGF-1 you inject to IGFBP3.

    While technically it is true that if you inject a large amount of the rhIGF-1 it will have almost only localized effect, it is so because the "excess" that does not bind to cells in the muscle in which it is injected is rapidly bound up by IGFBP3 and thus rendered unusable by cells elsewhere. It would be much much better in such a case to inject a smaller amount and not have ANY excess that gets bound up by IGFBP's.

    And while technically it is true that if you inject a large amount of Long R3 IGF-1 in a muscle, it will first bind to the nearest available receptor, and spread, binding to more and more receptors and not be bound up and neutralized by IGFBP's, meaning that it will travel all through your body and grow all kinds of tissue. This is called the systemic effect of IGF-1. Therein lies the only distinction in terms of BOTH half-life and localized/systemic effect between the Long and the human varieties.

    What does all this mean?

    It means that technically, for the part of the muscle in which you inject, THERE IS NO DIFFERENCE BETWEEN rhIGF-1 and Long R3 IGF-1. They both have the EXACT SAME LOCAL EFFECT. But rhIGF-1 gets neutralized quick, whereas Long R3 gets to float around until it finds a receptor.

    What does all this tell us?

    It tells us many things. Let's start with what we want, then see where that leads us. What do we want? Bigger muscles. More muscle cells that we will later grow with exercise and gear. A pump? Fatloss? Yeah, right. You can get a pump with a good "pump" product for a quarter of the price of IGF-1. Fatloss? Clen/Alb and T3/T4 will give it to you again at a fraction of the price of IGF-1. More muscle cells, you can ONLY get with IGF-1 (and MGF too). Nothing else will give it to you and if you are using IGF-1 for anything else, you are misusing it. More muscle cells is CLEARLY the best use for IGF-1.

    What does all this tell us?

    It tells us that we should use IGF-1 to make more muscle cells. It's the only thing that can give it to us and more cells is more growth, which is our goal.

    What does this tell us?

    The localized effects are the best. Long R3 IGF-1 can float around your body and attach to anything that has IGF-1 receptors. The intestines is the place that has the MOST IGF-1 receptors and it also happens to have lots of blood flow. Injecting large amounts of Long R3 ENSURES that you are growing your intestines. Remember, more cells doesn't equal more size right away. Wait a bit, and see them grow.

    What does this mean?

    It means that if you are injecting upwards of 50mcg of IGF-1 you are growing your intestines. Yes you are also growing muscle and you may be getting leaner in the process. Your waistline looks trimmer. Nice. A few months down the line, your new intestinal cells will be of their full adult size and you will have acquired the perma-bloat look. Guaranteed. Maybe not Coleman-size perma-gut, but SOME perma-gut and it will keep growing. Guaranteed. Just as your new muscle cells can keep growing and growing IF you pin IGF-1 in a way to maximize new muscle cell creation.

    HOW?

    Heavy resistance exercise strongly upregulates the IGF-1 receptors on the stressed muscle. That means that after your workout, the muscles you trained are at their BEST STATE for receiving IGF-1 and growing many new cells. That's when you pin. This upregulation of IGF-1 receptor during exercise is short-lived. The science is not readily available so I am unable to quote a paper, but within 60 minutes of the last set, the receptors are back at baseline. This means, PIN IMMEDIATELY POSTWORKOUT and you will get your new muscle cells. PIN A LESSER AMOUNT and you will get only new MUSCLE cells out of your IGF-1. Pin more and you will grow other things, including stuff you wish you didn't grow.

    What else?

    All the talk about IGF-1's half-life is UTTER BULLSHIT. It is technicality without any real-world applicability. Yes rhIGF-1 has a "short half-life". But what does it mean? It means that it is either taken up by a cell receptor or bound up by a binding protein in short order. Does it mean that 20 minutes after the IGF-1 is pinned you should pin more because "blood levels are low"? Not by any means. Once it's activated a cell receptor, that's where it initiates a cellular response that will take about 72 hours to be complete and which will consume lots of energy. So the half-life of 20 minutes means NOTHING BECAUSE THE EFFECTS STILL LAST 72 HOURS ALL THE SAME.

    What about Long R3 IGF-1?

    Yes technically it has a longer half-life. Why? Because it either gets rapidly taken up by a cell receptor or... Just floats around. Until it can find a receptor or is destroyed by the immune system or some other metabolizing mechanism. BUT THIS MEANS*NOTHING!!! Why does it mean nothing? BECAUSE once it attaches to a cell receptor, it initiates a cellular response that will take about 72 hours to be complete. THIS CELLULAR RESPONSE IS ALL THAT INTERESTS US. Not "blood levels", that's utter bullshit. As a matter of fact, the one thing YOU DO NOT WANT IS FOR BLOOD LEVELS OF IGF-1 TO BE ELEVATED. Because that means you are growing everywhere and this means first and foremost your guts. Sure it feels like it's working while you're on. Just you wait 9 months and see that you look like Craig Kovacs. Bravo, you now have the biggest intestines in the world.

    Half-life means nothing. Localized vs systemic = bad argument. You want localized effects. Period. You get them by pinning immediately postworkout. Period. End of argument.

    OMFG I am so tired of all the misinformation floating around on IGF-1. Look at the length of this post. Did you read all of it? You should, you know.




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    "And while technically it is true that if you inject a large amount of Long R3 IGF-1 in a muscle, it will first bind to the nearest available receptor, and spread, binding to more and more receptors and not be bound up and neutralized by IGFBP's, meaning that it will travel all through your body and grow all kinds of tissue. This is called the systemic effect of IGF-1." That was from your post. Obviously you know that cuz you just posted it..
     

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    Quote Originally Posted by Big Beef View Post
    "And while technically it is true that if you inject a large amount of Long R3 IGF-1 in a muscle, it will first bind to the nearest available receptor, and spread, binding to more and more receptors and not be bound up and neutralized by IGFBP's, meaning that it will travel all through your body and grow all kinds of tissue. This is called the systemic effect of IGF-1." That was from your post. Obviously you know that cuz you just posted it..
    I posted that because it's from Dave palumbo, lots of facts but didn't post second one fell asleep.
    I don't believe all of every thing posted or that I copy and paste but I cannot alter an author's article
    This systematic growth is unclear and I don't believe it happens, without hgh only or combination of IGF and hgh
    Will work on thread this is your review
    Sorry brother!
    Just know that nobody has became a huge monster from IGF alone at any given time.
    Healing and growth are used one in same but I call growth having a size of xx and using something and becoming a size of xxx even after a year or so.
    The more cell situation is very slow.
    And if synthetic IGF travels why would we want it to grow what we don't want.

    All IGF half life means is that it is resistant to antigens in our body that destroy it for longer.
    One bound to receptor every form last same amount of time with its reaction

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    It actually say false about travel

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    The point I was trying to make was igf levels are raised in blood with hgh on labs work!! But not with synthetic IGF use!!
    So either something else needs to happen to make it more active like a gh release or use it locally to attach to receptors wanted!!!
    To get this travelling affect u would have to use a shit ton. But we want muscles to grow not other things. So use in muscles I now feel best time for use is post workout no matter what.
    We want a natural Hgh release from Gherilin signal empty stomach. Carbing up before workout for a pump will be good for a pump with IGF but those carbs will stop even a natural gh release.
    So use post workout of final 15 minutes of workout and eat after workout.
    Only use protien low carb for that hour before workout.
    This is my believe in best way

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    IGF-1 is good stuff!
    Likes Muscle mechanic, Big Beef liked this post
     
    Area-1255;"the last of the honest bloggers".
    Well-versed in Pharmacology/Pharmacodynamics, Computer Security, Strength Training, and...The Craziest Push-Ups you've Never Seen

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    Igf-1 lr3 round 2

    Igf-1 lr3 round 2

    Igf-1 lr3 round 2

    Igf-1 lr3 round 2


    Igf-1 lr3 round 2

    Igf-1 lr3 round 2

    Igf-1 lr3 round 2
    Quote Originally Posted by Area 1255 View Post
    IGF-1 is good stuff!
    Yes it is. MC igf is for sure.

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