drtbear1967
Musclechemistry Board Certified Member
theguerillachemist<!-- react-text: 40 -->
There is a lot of information on SARMs on the Internet, some is decent but most is grossly inaccurate. This is my opinion on them as muscle builders and their purpose in bodybuilding. First off, these were all developed by pharmaceutical companies, which means a ton of time and MONEY($millions easily) went into developing these compounds. This begs the obvious question: why were they looking into to begin with? SARMs were first investigated with the purpose of attempting to separate the anabolic activities from the androgenic effects of AAS. Steroids are prescribed for a bunch of reasons, including anemia, burn victim healing, cachexia, as well as hormone replacement. If you have a female burn victim or cancer patient, you want the anabolic effects of muscle building and preventing muscle loss, but you don't want to go bald, get severe acne and experience virilization. SARMs are safe for women in the doses used in the literature. They have to be or they would lose 50% of the target demographic. However, when I see people using 50mg of Ostarine stacked with 20mg of LDG, these doses are not only very high, but they don't really bring out the benefits of why these compounds were made- to have a safe oral anabolic. At high doses, the androgenic and cardiovascular effects start to manifest and this completely defeats the purpose. From my research and experience with them(I worked on SARMs in grad school) I find that using them in a low dose manner is the safest way to increase lean muscle. SARMs are a slow and steady type of drug. Most studies show them to be virtually side effect free(at low doses) for at least 3 months. I posted before about the negative impact LGD and Ostarine can have on your cholesterol at the low doses used, imagine if you are taking 10-15x the dose(clinical dose for LGD was <1mg). I think SARMs have their place for women and men, however you need to educate yourself. Small doses over time will lead to increases in LBM and possible decreases in body fat. Some people "bridge" with SARMs. I don't believe in bridging bc you're never really "off" and you're still activating the AR. Having said that, low dose SARM can be used to bridge safely.
There is a lot of information on SARMs on the Internet, some is decent but most is grossly inaccurate. This is my opinion on them as muscle builders and their purpose in bodybuilding. First off, these were all developed by pharmaceutical companies, which means a ton of time and MONEY($millions easily) went into developing these compounds. This begs the obvious question: why were they looking into to begin with? SARMs were first investigated with the purpose of attempting to separate the anabolic activities from the androgenic effects of AAS. Steroids are prescribed for a bunch of reasons, including anemia, burn victim healing, cachexia, as well as hormone replacement. If you have a female burn victim or cancer patient, you want the anabolic effects of muscle building and preventing muscle loss, but you don't want to go bald, get severe acne and experience virilization. SARMs are safe for women in the doses used in the literature. They have to be or they would lose 50% of the target demographic. However, when I see people using 50mg of Ostarine stacked with 20mg of LDG, these doses are not only very high, but they don't really bring out the benefits of why these compounds were made- to have a safe oral anabolic. At high doses, the androgenic and cardiovascular effects start to manifest and this completely defeats the purpose. From my research and experience with them(I worked on SARMs in grad school) I find that using them in a low dose manner is the safest way to increase lean muscle. SARMs are a slow and steady type of drug. Most studies show them to be virtually side effect free(at low doses) for at least 3 months. I posted before about the negative impact LGD and Ostarine can have on your cholesterol at the low doses used, imagine if you are taking 10-15x the dose(clinical dose for LGD was <1mg). I think SARMs have their place for women and men, however you need to educate yourself. Small doses over time will lead to increases in LBM and possible decreases in body fat. Some people "bridge" with SARMs. I don't believe in bridging bc you're never really "off" and you're still activating the AR. Having said that, low dose SARM can be used to bridge safely.
