<center>NFL Point Spreads For Week 10 - Week Ten NFL Football Point Spread - NFL Spreads 11/10 - 11/14, 2016</center>
| Date & Time | Favorite | Spread | Underdog |
| 11/13 1:00 ET | At Jacksonville | -2.5 | Houston |
| 11/13 1:00 ET | At Carolina | -3 | Kansas City |
| 11/13 1:00 ET | At New Orleans | -3 | Denver |
| 11/13 1:00 ET | At NY Jets | -1 | Los Angeles |
| 11/13 1:00 ET | Atlanta | -1 | At Philadelphia |
| 11/13 1:00 ET | At Washington | -2 | Minnesota |
| 11/13 1:00 ET | Green Bay | -2.5 | At Tennessee |
| 11/13 1:00 ET | Chicago | -2.5 | At Tampa Bay |
| 11/13 4:05 ET | At San Diego | -4 | Miami |
| 11/13 4:25 ET | At Arizona | -14 | San Francisco |
| 11/13 4:25 ET | At Pittsburgh | -3 | Dallas |
| 11/13 8:30 ET | At New England | -7.5 | Seattle |
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| 11/14 8:30 ET | Cincinnati | -1 | At NY Giants |
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