It's been so long sice I've used it, it's like my forgotten aid. Great post. Good infor and furthermore a good product.
I was thinking about adding Proviron to my upcoming cycle...I've used it once in the past and I really liked it. It's good for that hard vascular look. It's an effective anti-e and it's also good for increasing your sex drive and many other things. Below is some more information about it:
Oral androgen for the treatment
of male patients
1 tablet contains mesterolone (17beta-hydroxy-1alpha-methyl-5alpha-androstan-3-one) 25 mg and the preservatives methylparaben (0,02%) and propylparaben (0,01%).
A. 21.7 Male sex hormones.
Proviron balances a deficiency of androgen formation which begins to fall gradually with increasing age. Therefore, Proviron is suitable for treatment of all conditions caused by deficient endogenous androgen formation. In the recommended therapeutic dosage, Proviron will not impair spermatogenesis. Proviron is especially well tolerated by the liver.
• Declining physical activity and mental alertness in middle- and old-aged men
Reduced efficiency, easy fatigability, lack of concentration, weak memory, disturbances of libido and potency, irritability, disturbances of sleep, depressive moods, and general vegetative complaints are often attributed to androgen-deficiency. These complaints can be overcome or improved by the use of Proviron tablets.
• Potency disturbances
Proviron overcomes potency disturbances due to androgen-deficiency. It may also be of use as supplementary therapy in cases of diminished potency where androgen-deficiency is not the primary cause.
Growth, development and function of androgen-dependent target organs are stimulated by Proviron. It promotes development of secondary male sex characteristics in cases of prepuberal hypogonadism. Full clinical and laboratory investigations are necessary in all cases of young patients prior to commencement of treatment. Proviron tablets may also be used as a substitution therapy in cases where a loss of gonadal function has occurred post-puberally.
Oligozoospermia and deficient Leydig-cell secretion may be the cause of infertility. With Proviron treatment, sperm count can be increased, the quality improved and, furthermore, a higher fructose concentration up to normal values can be achieved thus increasing the chances of procreation.
In patients with carcinoma of the prostate, androgen therapy of any kind, including the use of Proviron, is contra-indicated.
DOSAGE AND DIRECTIONS FOR USE
If not otherwise directed by the physician, the following dosage is recommended:
In declining physical activity and potency disturbances
Commencement of treatment: 1 Proviron tablet of 25 mg three times daily.
Continuation of treatment: 1 Proviron tablet of 25 mg twice or once daily.
According to type and severity of the complaints, a course of Proviron lasting four to six weeks or a prolonged uninterrupted treatment over several months is recommended. If required, the course of treatment may be repeated several times.
Hypogonadism requires continuous therapy
For development of secondary male sex characteristics 1 Proviron tablet of 25 mg 3-4 times daily for several months. As maintenance dose 1 Proviron tablet of 25 mg twice or three times daily will be sufficient.
1 Proviron tablet of 25 mg twice or three times daily for a cycle of spermatogenesis, ie 90 days.
In case of simultaneously impaired gonadotrophic excretion, a combined therapy with gonadotrophic hormone exhibiting FSH activity is recommended for the commencement of treatment (eg 2000 IU serum gonadotrophin im twice weekly up to a total amount of 12 000 IU). If necessary, Proviron treatment is to be repeated after an interval of several weeks.
and even more information...
Mesterolone is an orally active, 1-methylated DHT. Like Masteron, but then actually delivered in an oral fashion. DHT is the conversion product of testosterone at the 5-alpha-reductase enzyme, the result being a hormone that is 3 to 4 times as androgenic and is structurally incapable of forming estrogen. One would imagine then that mesterolone would be a perfect drug to enhance strength and add small but completely lean gains to the frame. Unfortunately there is a control mechanism for DHT in the human body. When levels get too high, the 3alpha hydroxysteroid dehydrogenase enzyme converts it to a mostly inactive compound known as 3-alpha (5-alpha-androstan-3alpha,17beta-diol), a prohormone if you will. It can equally convert back to DHT by way of the same enzyme when low levels of DHT are detected. But it means that unless one uses ridiculously high amounts, most of what is administered is quite useless at the height of the androgen receptor in muscle tissue and thus mesterolone is not particularly suited, if at all, to promote muscle hypertrophy.
Proviron has four distinct uses in the world of bodybuilding. The first being the result of its structure. It is 5-alpha reduced and not capable of forming estrogen, yet it nonetheless has a much higher affinity for the aromatase enzyme (which converts testosterone to estrogen) than testosterone does. That means in administering it with testosterone or another aromatizable compound, it prevents estrogen build-up because it binds to the aromatase enzyme very strongly, thereby preventing these steroids from interacting with it and forming estrogen. So Mesterolone use has the extreme benefit of reducing estrogenic side-effects and water retention noted with other steroids, and as such still help to provide mostly lean gains. Its also been suggested that it may actually downgrade the actual estrogen receptor making it doubly effective at reducing circulating estrogen levels.
The second use is in enhancing the potency of testosterone. Testosterone in the body at normal physiological levels is mostly inactive. As much as 97 or 98 percent of testosterone in that amount is bound to sex hormone binding globulin (SHBG) and albumin, two proteins. In such a form testosterone is mostly inactive. But as with the aromatase enzyme, DHT has a higher affinity for these proteins than testosterone does, so when administered simultaneously the mesterolone will attach to the SHBG and albumin, leaving larger amounts of free testosterone to mediate anabolic activities such as protein synthesis. Another way in which it helps to increase gains. Its also another part of the equation that makes it ineffective on its own, as binding to these proteins too, would render it a non-issue at the androgen receptor.
Thirdly, mesterolone is added in pre-contest phases to increase a distinct hardness and muscle density. Probably due to its reduction in circulating estrogen, perhaps due to the downregulating of the estrogen receptor in muscle tissue, it decreases the total water build-up of the body giving its user a much leaner look, and a visual effect of possessing "harder" muscles with more cuts and striations. Proviron is often used as a last-minute secret by a lot of bodybuilders and both actors and models have used it time and again to deliver top shape day in day out, when needed. Like the other methylated DHT compound, drostanolone, mesterolone is particularly potent in achieving this feat.
Lastly Proviron is used during a cycle of certain hormones such as nandrolone, with a distinct lack of androgenic nature, or perhaps 5-alpha reduced hormones that don't have the same affinities as DHT does. Such compounds, thinking of trenbolone, nandrolone and such in particular, have been known to decrease libido. Limiting the athlete to perform sexually being the logical result. DHT plays a key role in this process and is therefore administered in conjunction with such steroids to ease or relieve this annoying side-effect. Proviron is also commonly prescribed by doctors to people with low levels of testosterone, or patients with chronic impotence. Its not perceived as a powerful anabolic, but it gets the job done equally well if not better than other anabolic steroids making it a favorite in medical practices due to its lower chance of abuse.
Mesterolone is generally well liked nonetheless as it delivers very few side-effects in men. In high doses it can cause some virilization symptoms in women. But because of the high level of deactivation and pre-destination in the system (albumin, SHBG, 3bHSD, aromatase) quite a lot of it, if not all simply never reaches the androgen receptor where it would cause anabolic effects, but also side-effects. So its relatively safe. Doses between 25 and 250 mg per day are used with no adverse effects. 50 mg per day is usually sufficient to be effective in each of the four cases we mentioned up above, so going higher really isn't necessary. Unlike what some suggest or believe, its not advised that Proviron be used when not used in conjunction with another steroid, as it too is quite suppressive of natural testosterone, leading to all sorts of future complications upon discontinuation. Ranging from loss of libido or erectile dysfunction all the way up to infertility. One would not be aware of such dangers because Proviron fulfills most of the functions of normal levels of testosterone.
Stacking and Use:
Mesterolone is an oral alkylated steroid. If used primarily as an anti-aromatase drug, using it throughout a longer cycle (10-12 weeks) of injectables may elevate liver values a little bit, though much, much less than one would expect with a 17-alpha-alkylated steroid. Eventhough instead of inhibiting gains, mesterolone may actually contribute to gains. So that's a bit of a shame. Its not quite as toxic since its not alkylated in the same fashion, but at the 1 position, which reduces hepatic breakdown, but not like 17-alpha alkylation. The reason for the change of position I assume, is because alkylating at the 17-alpha position has been shown to reduce affinity for sex hormone binding proteins. This would in turn decrease its ability to free testosterone. Nonetheless the delivery rate is quite good. Its taken daily in 50-100 mg doses.
The best thing to stack it with is testosterone of course. Its most easily bound to SHBG and albumin, and deactivated for up to 98%. Since the DHT can compete for these structures with higher affinity it would naturally lead to a higher yield of whatever testosterone product you stacked it with. Since DHT levels are notably higher now there is also more stimulation of the androgen receptor causing more strength gains, and because of its affinity for aromatase the overall estrogen level decreases as well. This has as a result that gains are leaner, and once again the overall testosterone yield is increased as less I converted at the aromatase enzyme.
It's of course used in other stacks with products such as methandrostenolone, boldenone and nandrolone to reduce estrogenic activity and increase muscle hardness. The addition of proviron makes boldenone a dead lock for a cutting stack and for some may even make it possible to use nandrolone while cutting, although the use of Winstrol or a receptor antagonist in conjunction is wishful as well. The benefit of adding it to a nandrolone stack is that it may also help you reduce the decrease in libido suffered from nandrolone, since the latter is mostly deactivated by 5-alpha reductase, an enzyme that makes other hormones more androgenic.
Proviron is an anti-aromatase, so obviously anti-estrogens would be futile and redundant. Blood pressure medication for those prone to hypertension may be wise, as this DHT can increase the blood pressure. - by Big Cat
So as you can see this is some good shit. lol. So try it some time and let us know what you think.
It's been so long sice I've used it, it's like my forgotten aid. Great post. Good infor and furthermore a good product.
As always, these posts are for entertainment purposes only. Not to be taken as medical advice, or even serious for that matter.
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i was thinking of running it post cycle....it just has some sweet capabilities during your post cycle therapy.....keep alot of your hard earned meat this way
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Bignick is a fictional character and therefore all information given by Bignick is for entertainment purposes only. Bignick does not condone nor support the use of Anabolic Steroids or any other controlled substances.
Great post bro....
Is it possible to run proviron with Eq and winny without Test for just the end of a test/eq/winny cycle?...I have heard good things about proviron....
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yes...it will keep your androgen levels up. It's reletively inexpensive and fairly easy on the body too. Lots of guys use it when they don't want to use test to keep their sex drive up.
One of the biggest things that caught my eye was the fact that it has a higher affinity for binding to SHBG. This will give you more bang for your buck with test only cycles or just any cycle in general. Something like 98% of your test gets bound to SHBG leaving it basically useless for muscle building. Proviron (basically DHT) will bind to the shbg receptors leaving more free test. (increased free test levels on bloodwork)
2 to 3 25mg tablets a day should do ya pretty good.
How the hell did I miss this one? That is great info to know since I am on HRT. I have had to use oral replacement when I went to Brazil since I couldn't bring my normal gear with me. My doc gave me methlytestosterone for use while I was down there. He is obviously not very educated about AAS or he wouldn't have given me that since there are other orals that are far less toxic than that one--can't have much fun if you're on an oral like that. Proviron sounds like an excellent alternative, and I will be sure to mention it the next time I have to use an oral. I may even ask for a 90-day trial of it to see how my body reacts to it, and it sounds from the above info that it would be excellent to use at the same time as my regular test cyp. Maybe I should hit my doc up to see if I can use both....hmmm...
Blast from the past, wow. I never could convince my doc to let me try that one. Orals like this are a little harder to find these days--at least for me it has been hard (probably not looking in the right places, lol). I'm still convinced it would be a great addition to my HRT so I'm going to see if I can find it.
for the past week I've been running a low dose of 25mg/day, MWF i'm using axio proviron (proley underdosed) and T,TH,S,Sun using schering and i plan on running it for a few more weeks, but i can say i do notice the added effects of proviron, ecspecially the sex drive
i will start my first cycle after 12 years tomorrow monday. am 37 YEARS OLD 5'10' 182 pounds and 17 0/0 bodyfat. i have (eq,primo and test propionate) and in tablets var,winny,proviron,nolvadex,clomid. so i will going vac on a cruise by the end of april ...so whats could be a first injectable alone or stack ???? w any tablets?????? .i wanna get lean and gain some weight .will be 9 days in the ship. want to take advantage of all a lot food of course good quality prot,carbs ,fats and they have a gym so any advice from you more experience builders?????????