drtbear1967
Musclechemistry Board Certified Member
theguerillachemist
This is one of my favorite "prosteroid" compounds from the early 2000s. Desoxymethyltestoserone, AKA Madol and Pheraplex, is an active anabolic steroid that was introduced to the market in 2005 by Patrick Arnold...suprise surprise lol. Structurally, Madol is a very interesting molecule. If you compare it to test, Madol is missing the 3-keto group (C=O) that is usually important to binding to the AR. Instead, it has a double bond at carbon 2, which makes it bind slightly weaker than DHT. It is a very anabolic compound, with a 6.5:1 ratio vs testosterone. Interestingly, Madol has very high selectivity towards being anabolic vs androgenic, almost like a SARM, except this is steroidal in nature. It stimulated skeletal muscle growth with no prostate growth in rats, very rare for a steroid. It is methylated at carbon 17, so liver toxicity was an issue. I personally used this when it was available and thought it was awesome. Sadly, in 2010, Madol was banned and is now a schedule III steroid. Worth noting: Madol is very close in structure to epistane, which has a thiol ring where the carbon 2 double bond is on Madol. If fact, some epistane products could decompose into Madol under certain conditions
This is one of my favorite "prosteroid" compounds from the early 2000s. Desoxymethyltestoserone, AKA Madol and Pheraplex, is an active anabolic steroid that was introduced to the market in 2005 by Patrick Arnold...suprise surprise lol. Structurally, Madol is a very interesting molecule. If you compare it to test, Madol is missing the 3-keto group (C=O) that is usually important to binding to the AR. Instead, it has a double bond at carbon 2, which makes it bind slightly weaker than DHT. It is a very anabolic compound, with a 6.5:1 ratio vs testosterone. Interestingly, Madol has very high selectivity towards being anabolic vs androgenic, almost like a SARM, except this is steroidal in nature. It stimulated skeletal muscle growth with no prostate growth in rats, very rare for a steroid. It is methylated at carbon 17, so liver toxicity was an issue. I personally used this when it was available and thought it was awesome. Sadly, in 2010, Madol was banned and is now a schedule III steroid. Worth noting: Madol is very close in structure to epistane, which has a thiol ring where the carbon 2 double bond is on Madol. If fact, some epistane products could decompose into Madol under certain conditions
