That spread makes sense because ostarine (MK-2866) is one of the milder SARMs, so people chasing lean, quality gains often find a lower dose is enough, while others push higher and get more suppression without much extra benefit. For your size and goal, I would agree with the guys saying 25 mg...
I agree with the others here — don't chase a maximum dose. Starting at 1 mg a week and staying there for a few weeks lets you see how your appetite and stomach handle it, then you can move up in small steps only if you need to. At 350 lb with about 100 lb to lose, slow and steady titration will...
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