1. #1
    Iron Game's Avatar
    Join Date
    Apr 2008
    Location
    MD
    Age
    51
    Posts
    5,060
    Rep Power
    2147488723

    Default Nandrolone: Bad for Doping, Good for Hormone Replacement

    by Anthony Roberts
    I cringe every time an athlete gets caught using Nandrolone (Deca). Its reputation as an incredibly effective anabolic steroid is perhaps only surpassed by its reputation for being easy to detect. It’s one of the eighteen steroids that every standard doping screen tests for. It generates a ton of well-documented metabolites, which last for up to eighteen months. And it has a very low threshold for detection. It’s literally the worst choice an athlete can make, if they’re going to be tested.



    But it’s so damn effective.

    Nandrolone (often called Deca, after the trade name “Deca-Durabolin”) has been widely used since the ’80s, and was likely the single most popular anabolic steroid straight through into the ’90s. It was (and still is) used successfully by bodybuilders and powerlifters for everything from gaining muscle to losing fat, and getting stronger alone the way.


    Still, thats what steroids do: they help people get bigger, leaner, and stronger. What makes Nandrolone unique is its effects on joints…for whatever reason, it just makes joints feel better; heavy lifts don’t hurt and old injuries seem to disappear. Nandrolone increases gastrointestinal and renal tubular absorption of calcium and decreases bone re-absorption, while also stimulating formation of extra-osseous collagen and soft tissue. Nandrolone doesn’t just make you “feel” better, it helps to heal you.


    An intreresting fact about Nandrolone’s positive effects on joints and connective tissue is that bodybuilders and powerlifters were the first to discover them, and only later did the scientific and medical community begin performing studies that confirmed this trait.


    It’s really an ideal steroid for athletes – which sucks, because it’s probably the single easiest steroid to detect in urine. So while it’s an awful choice for drug-tested athletes (read: the worst), it’s a really great choice for anyone else…especially men on hormone replacement therapy.



    Structurally, Nandrolone is testosterone with one less carbon atom at the 19th position – which is why it’s often referred to as 19-nor testosterone (nor is a negative clause, meaning “not” – so it’s literally testosterone, but not at the 19th position, where it’s missing that carbon). This modification allows it to binds to androgen receptors with a greater affinity than testosterone and gives it a higher anabolic rating with a lower androgenic component. It also makes it far less susceptible to conversion into a 5alpha-reduced version (and when it does, it’s not very potent), which means it’s far less likely to cause hair loss also. Similarly, it converts to estrogen at roughly 20% the rate of testosterone.


    I’m not saying anyone should trade in their testosterone shots for Deca shots…I’m saying they should be used together. This is partly because Nandrolone has also been shown to be somewhat harsh on hormone levels, causing a rapid and severe shutdown of natural testosterone. And partly because most steroid users find that Deca-only cycles result in a degree of sexual dysfunction (the dreaded “Deca Dick”), which is ameliorated by the addition of testosterone. This is why nandrolones, and in fact all 19-nor steroids (trenbolone, etc…) are almost never used without additional testosterone.


    Dan Duchaine once wrote that after the age of 40, men using testosterone for hormone replacement should switch their total weekly milligrams to 50% Nandrolone. If I were recommending the addition of Nandrolone to a hormone replacement regimin, I’d probably be a bit more conservative and say that it should be used at half the testosterone dose. But if I were given free reign to design my own hormone replacement program, and not constrained by legality, I’d add an equal amount of a long-estered DHT derivative, likely Methenolone (Primobolan) to my Nandrolone (at an equal dose, half that of the testosterone – for a grand total of 400ms/week).


    References:
    • Novel Uses for the Anabolic Androgenic Steroids Nandrolone and Oxandrolone in the Management of Male Health.Wu C, Kovac JR.Curr Urol Rep. 2016 Oct;17(10):72. doi: 10.1007/s11934-016-0629-8. Review.
    • Beyond testosterone cypionate: evidence behind the use of nandrolone in male health and wellness. Transl Androl Urol. 2016 Apr; 5(2): 213–219.Michael M. Pan and Jason R. Kovac.
    • Geusens P. Nandrolone decanoate: pharmacological properties and therapeutic use in osteoporosis. Clin Rheumatol 1995;14 Suppl 3:32-9. 10.1007/BF02210686
    • Kicman AT.. Pharmacology of anabolic steroids. Br J Pharmacol 2008;154:502-21. 10.1038/bjp.2008.165
    Likes LeatherHead, KngShisa, nixter liked this post
     
    Your Character Is In Your DEEDS. Not Your Dreams!

    Follow Me twitter Iron-Game

  2. #2
    Musclechemistry Board Certified Member Board Certified MD
    drtbear1967's Avatar
    Join Date
    Aug 2016
    Location
    Kentucky
    Posts
    5,663
    Rep Power
    2147489318

    Default

    KING DECA!! Anyone with joint issues should be doing at least a cc per week or more.
    Likes LeatherHead, HULK1972, KngShisa, Iron Game liked this post
     
    Get It Done!

  3. #3
    MuscleChemistry Guru Board Certified MD
    LeatherHead's Avatar
    Join Date
    Aug 2009
    Location
    FLORIDA
    Posts
    6,061
    Rep Power
    2147489723

    Default

    I'm thinking about ditching the tren for a while and going back to deca.
    Likes drtbear1967, Iron Game liked this post
     
    Fear No Man In This World... Nor the Next

  4. #4
    MuscleChemistry Newbie Board Certified D.V.M.

    Join Date
    Apr 2014
    Posts
    34
    Rep Power
    0

    Default

    I always use deca. No matter what, I gave up on tren a while ago. Its great but deca is king. The collagen properties, helping joints etc. Its to bad I cannot convince my Dr that deca along with TE or Tc is a far better hormone replacement. But he disagrees as he just believes it stops test production in its tracks, which is true but if I were producing T naturally I wouldn't need the replacement therapy lol and the benefits are widely know and documented but he won't bother to even look at the studies I've brought to him. I also believe 2 iu of some good ol serostims would work wonders for me personally,he thinks I just want a free legal cycle but the doses are low from what I use to use and real gh has so many positive benefits its insane. Getting the insurance company to pay for it would be another battle which is why I'm thinking Sarms are going to be my future because I have used ostarine plenty of times with great results mostly in pct and as a cruise but also on cycle and its a great compound and now with the GH producing sarm I feel its far better than the peptides but good igf is another alternative to add that will help and you can essentially use these in combinations as you age without as much risk of heart disease due to lipids or uncontrolled blood pressure which I know a ton of guys don't bother to check. I'm in my ex's and I'm not saying my days of cycling are quite done but they are farther apart, and fewer of them. Honestly I quit doing let's 5 years into it but my pct at one time did consist of ostarine, hcg, igf, torem, aromisin, and I honestly never felt like I came off. This was an experiment after cruising on a gram of T as my off time and I decided to attempy one pct especially with all the compounds that were out and I lost around 5 lbs of water weight then began to gain a little more than I lost after a couple of months. I didn't have real gh at the time so I didn't add that in which I believe real gh , meaning not generic and from a pharmacy I see it come out of should be part of a cycle and post cycle but with serostims or any good th I believe over 2 iu is a waste.

    Nandrolone I believe has been the sole hormone that provided all the thick muscle fibers that I gained thru the years and the great thing is I can now maintain a good size that I'm comfortable with just on TRT with some osta and igf , gh, or I may go with ligandrol to try it out but we need to find ways to maintain. And I've had some pretty bad spinal injuries and a couple other injuries and while I don't believe deca is going to cure them I think it should be included in my hormone replacement along with gh and all at Hormone Replacement doses which I understand my body was never making Nandrolone but I believe its a benefit

    Sent from my LG-H830 using Tapatalk
    Thanks drtbear1967 thanked for this post
    Likes yellow snow, Iron Game liked this post
     

  5. #5
    BigZ MC Site Admin Board Certified MD

    Join Date
    Jul 2013
    Posts
    2,106
    Rep Power
    2147485764

    Default

    Quote Originally Posted by drtbear1967 View Post
    KING DECA!! Anyone with joint issues should be doing at least a cc per week or more.
    Lol, that would be me!!
    Likes drtbear1967 liked this post
     

  6. #6
    BigZ MC Site Admin Board Certified MD

    Join Date
    Jul 2013
    Posts
    2,106
    Rep Power
    2147485764

    Default

    Quote Originally Posted by Userat204 View Post
    I always use deca. No matter what, I gave up on tren a while ago. Its great but deca is king. The collagen properties, helping joints etc. Its to bad I cannot convince my Dr that deca along with TE or Tc is a far better hormone replacement. But he disagrees as he just believes it stops test production in its tracks, which is true but if I were producing T naturally I wouldn't need the replacement therapy lol and the benefits are widely know and documented but he won't bother to even look at the studies I've brought to him. I also believe 2 iu of some good ol serostims would work wonders for me personally,he thinks I just want a free legal cycle but the doses are low from what I use to use and real gh has so many positive benefits its insane. Getting the insurance company to pay for it would be another battle which is why I'm thinking Sarms are going to be my future because I have used ostarine plenty of times with great results mostly in pct and as a cruise but also on cycle and its a great compound and now with the GH producing sarm I feel its far better than the peptides but good igf is another alternative to add that will help and you can essentially use these in combinations as you age without as much risk of heart disease due to lipids or uncontrolled blood pressure which I know a ton of guys don't bother to check. I'm in my ex's and I'm not saying my days of cycling are quite done but they are farther apart, and fewer of them. Honestly I quit doing let's 5 years into it but my pct at one time did consist of ostarine, hcg, igf, torem, aromisin, and I honestly never felt like I came off. This was an experiment after cruising on a gram of T as my off time and I decided to attempy one pct especially with all the compounds that were out and I lost around 5 lbs of water weight then began to gain a little more than I lost after a couple of months. I didn't have real gh at the time so I didn't add that in which I believe real gh , meaning not generic and from a pharmacy I see it come out of should be part of a cycle and post cycle but with serostims or any good th I believe over 2 iu is a waste.

    Nandrolone I believe has been the sole hormone that provided all the thick muscle fibers that I gained thru the years and the great thing is I can now maintain a good size that I'm comfortable with just on TRT with some osta and igf , gh, or I may go with ligandrol to try it out but we need to find ways to maintain. And I've had some pretty bad spinal injuries and a couple other injuries and while I don't believe deca is going to cure them I think it should be included in my hormone replacement along with gh and all at Hormone Replacement doses which I understand my body was never making Nandrolone but I believe its a benefit

    Sent from my LG-H830 using Tapatalk
    I have actually heard of some well-educated doctors giving both testosterone AND deca to their patients. They realize the benefits that it gives for the joints. It's well known that test cyp actually destroys joints down with long-term use. I'm in that boat having been on TRT for almost 18 years straight. Most docs however, will only prescribe it to you if you have HIV from what I have been told.
    Likes yellow snow liked this post
     

  7. #7
    MuscleChemistry Guru Board Certified CPH
    yellow snow's Avatar
    Join Date
    Jun 2015
    Posts
    1,835
    Rep Power
    2147485491

    Default

    Quote Originally Posted by BigZ View Post
    I have actually heard of some well-educated doctors giving both testosterone AND deca to their patients. They realize the benefits that it gives for the joints. It's well known that test cyp actually destroys joints down with long-term use. I'm in that boat having been on TRT for almost 18 years straight. Most docs however, will only prescribe it to you if you have HIV from what I have been told.
    The most progressive doc are actually prescribing mast with TRT. The mast helps control the Estrogen side you get from the T.
    Likes LeatherHead liked this post
     
    Beach bodies are made in the winter.

  8. #8
    MuscleChemistry Guru Board Certified MD
    freakinthegym's Avatar
    Join Date
    Jan 2008
    Location
    in the south
    Age
    41
    Posts
    2,292
    Rep Power
    2147485956

    Default

    Really?
    All information discussed on these forums is purely for entertainment purposes

  9. #9
    MuscleChemistry Guru Board Certified CPH
    yellow snow's Avatar
    Join Date
    Jun 2015
    Posts
    1,835
    Rep Power
    2147485491

    Default

    mast actually binds SHBG, which free up more T. You could use a 50/50 split of mast to T and work great on TRT.
    Beach bodies are made in the winter.

  10. #10
    Musclechemistry Board Certified Member Board Certified MD
    drtbear1967's Avatar
    Join Date
    Aug 2016
    Location
    Kentucky
    Posts
    5,663
    Rep Power
    2147489318

    Default

    So would you have 250 of cyp and 250 of mast
    Likes yellow snow, Iron Game liked this post
     
    Get It Done!

  11. #11
    MuscleChemistry Guru Board Certified CPH
    yellow snow's Avatar
    Join Date
    Jun 2015
    Posts
    1,835
    Rep Power
    2147485491

    Default

    Quote Originally Posted by drtbear1967 View Post
    So would you have 250 of cyp and 250 of mast
    He is not that progressive

    100mg of test
    100mg of mast
    Thanks Iron Game thanked for this post
    Likes Iron Game liked this post
     
    Beach bodies are made in the winter.

  12. #12
    Musclechemistry Board Certified Member Board Certified MD
    drtbear1967's Avatar
    Join Date
    Aug 2016
    Location
    Kentucky
    Posts
    5,663
    Rep Power
    2147489318

    Default

    gotcha!! How have you been doing Snow?
    Thanks yellow snow thanked for this post
     
    Get It Done!

  13. #13
    MuscleChemistry Guru Board Certified CPH
    yellow snow's Avatar
    Join Date
    Jun 2015
    Posts
    1,835
    Rep Power
    2147485491

    Default

    Quote Originally Posted by drtbear1967 View Post
    gotcha!! How have you been doing Snow?
    Great already in summertime shape, ( maybe 5 more pounds) abs are in but not as sharp as I like. Going to someplace warm and going to hit the beach!!
    Likes Iron Game liked this post
     
    Beach bodies are made in the winter.

Similar Threads

  1. HRT Hormone Replacement Therapy
    By Presser in forum Bodybuilding Steroid & Training Articles
    Replies: 20
    Last Post: 04-30-2020, 11:02 AM
  2. Hormone Replacement Therapy or Testosterone Replacement Therapy
    By big in vegas in forum MuscleChemistry Discussion
    Replies: 17
    Last Post: 04-08-2014, 05:27 PM
  3. I need help with Hormone Replacement Therapy
    By Suirad in forum MuscleChemistry Discussion
    Replies: 10
    Last Post: 11-12-2013, 09:34 PM
  4. Replies: 3
    Last Post: 10-22-2013, 01:08 AM
  5. Hormone Replacement Therapy
    By equilifemd in forum MuscleChemistry Discussion
    Replies: 1
    Last Post: 06-30-2011, 04:43 PM

Tags for this Thread

Posting Permissions

  • You may not post new threads
  • You may not post replies
  • You may not post attachments
  • You may not edit your posts
  •  

Log in

Log in