Drugs that deplete magnesium (Serms, Adex)

Muscle mechanic

MuscleChemistry Registered Member
These are drugs that deplete magnesium storage in our body's.

PLEASE NOTICE THAT SERMS AND ADEX LISTED AND MANY WE USE

A little about magnesium deficiency
The National Health and Nutrition Examination Survey (NHANES) of 2005–2006 found that the majority of people in the United States were*not getting enough magnesium in their diet.

However, the body can retain good levels of magnesium, so it is quite rare for a person to experience deficiency symptoms.

Certain factors can, however, increase a person's risk of developing magnesium deficiency symptoms. These include:

continually eating a low-magnesium diethaving gastrointestinal disorders such as*Crohn's disease,*celiac disease, or regional enteritislosing excessive amounts of magnesium through
urine and sweat
resulting from genetic disorders
or drinking too much alcohol
being pregnant
and lactatingbeing
hospitalized
having parathyroid disorders
and hyperaldosteronism
having*type 2 diabetes
being older
taking certain medications, such as proton pump inhibitors, diuretics, bisphosphonates, and*antibiotics

Long-term magnesium deficiency may have adverse effects on:

bone density
brain function
nerve and muscle function
digestive system

Loss of bone density can be of particular concern. In younger people, magnesium deficiency may prevent bone growth. It is vital to get enough magnesium during childhood when the bones are still developing.

In older people, magnesium deficiency may increase the risk of*osteoporosis*and*bone fractures.

Early signs of magnesium deficiency may include:

nausea
vomiting
loss of appetite
fatigue
weakness

As deficiency progresses, people may experience:

lower*calcium*levels in the blood, known as hypocalcemia
numbness and tingling in the extremities
cramps and muscle contractions
seizures
personality changes
abnormal heart rhythms
coronary spasms

Prolonged magnesium deficiency can have an adverse impact on a person's long-term health and increase the risk of chronic diseases, including:

heart
disease
high blood
pressure
type 2 diabetes
osteoporosis

Anyone who experiences any of the above symptoms should see a doctor for tests to establish the cause.

Diagnosis of magnesium deficiency varies between different countries. This is because it is difficult to accurately measure the amount of magnesium in a person's body. In the United States, doctors estimate a person's dietary intake to establish their magnesium status.

According to the*National Institutes of Health, the RDA for people between the ages of 19 and 30 years old is:

310mg for females
400mg for males

For people aged 31 years or older, the RDA is:

320mg for females
420mg for females

Requirements are higher in teenagers aged between 14 and 18 years old, as well as for those who are pregnant. Younger children require less magnesium than teenagers and adults.

It is possible to reach the RDA for magnesium by eating foods that contain high levels of magnesium, such as green vegetables, fruit, whole grains, cereals, and legumes.

Some foods high in magnesium, listed from highest to lowest magnesium content,*include:

nuts,
especially almonds,
cashews,
peanuts
spinach
black beans
edamame
peanut butter
whole wheat bread
avocado
potato
rice
yogurt
fortified cereals and other foods

Other foods containing magnesium include:

oatmeal
Cyclosporine (Sandimmune, Neoral)
Tacrolimus (Prograf)
kidney beans
banana*and apples
fish, such as salmon and halibut
milk
raisins
chicken breast
beef
broccoli and carrot

When magnesium levels are low, the body absorbs extra magnesium from the small intestine, while reducing the amount that is excreted by the kidneys

Certain nutrients and conditions can affect how much magnesium a person absorbs. People wanting to increase their magnesium levels by improving absorption could try:

reducing or avoiding calcium-rich foods two hours before or after eating
magnesium-rich foods
avoiding high-dose zinc supplements
treating*vitamin D*deficiency
eating raw vegetables instead of cooking them
quitting smoking

Magnesium is also crucial for liver function and glutathione!!!

Here are meds that reduce magnesium...

ACE inhibitors:

Enalapril and HCTZ (Vaseretic)

Angiotensin II receptor blockers:

Valsartan and HCTZ (Diovan HCT)

Diuretics, loop:

Bumetanide (Bumex)
Ethacrynic acid (Edecrin)
Furosemide (Lasix)
Torsemide (Demadex)

Diuretics, thiazide (and any combination drug that contains HCTZ or hydrochlorothiazide—dozens of drugs contain this)

Candesartan and HCTZ (Atac and HCT)Chlorothiazide
(Diuril)Chlorthalidone (Hygroton)Hydrochlorothiazide or HCTZ (Hydrodiuril)
Methyclothiazide (Enduron)
Metolazone (Zaroxolyn)

Diuretics, potassium-sparing:

Possibly the potassium-sparing diuretics, however this is not conclusive

Diuretics, sulfonamide:

Indapamide (Lozol)
Cardiac Glycoside Digoxin (Digitek, Lanoxicaps, Lanoxin
Betamethasone (Diprolene, Luxiq)
Dexamethasone(Decadron)
Hydrocortisone (Cortef)
Methylprednisolone (Medrol)
Mometasone (Elocon)
Prednisolone (PediapredLiquid)
Prednisone (Deltasone, Liquid Pred, Sterapred)
Triamcinolone (Aristocort cream)

Inhaled corticosteroids:

Flunisolide (Nasarel, Nasalide)
Futicasone (Flonase)
Triamcinolone (Azmacort inhaler)

Diethylstilbestrol (DES)
Estradiol (Activella, Climara, Combipatch, Estrace, Estraderm, Estring, EstroGel, Femring, Menostar, and many others)
Estrogen-containing drugs (hormone replacement therapy and birth control)
Estrogens, conjugated (Premphase, Prempro)
Estrogens, esterified (Estratab)
Estropipate (Ogen)
Ethinyl estradiol (found in many birth control pills)
Levonorgstrel (found in many birth control pills)
Cyclosporine (Sandimmune, Neoral)
Tacrolimus (Prograf)

Acid Blockers

Cimetidine (Tagamet)
Esomeprazole (Nexium)
Famotidine (Pepcid and Pepcid Complete)
Nizatidine (Axid)
Omeprazole (Prilosec OTC)
Pantoprazole (Protonix)
Ranitidine (Zantac)
Rabeprazole (Aciphex)

*

Antacids

Aluminum and magnesium hydroxide (Maalox, Mylanta)
Aluminum carbonate gel
(Basaljel)
Aluminum hydroxide (Amphojel, AlternaGEL
)Calcium carbonate (Tums, Titralac, Rolaids)
Magnesium hydroxide (Phillips’ Milk of Magnesia)
Sodium bicarbonate (Alka-Seltzer, baking soda)
Antibiotics (a few examples)
Amoxicillin (Amoxil)
Azithromycin (Z-Pak)
Cefaclor (Ceclor)
Cefdinir (Omnicef)
Cephalexin (Keflex)
Ciprofloxacin (Cipro)
Clarithromycin (Biaxin)
Doxycycline (Doryx)
Erythromycin (E.E.S.)
Levofloxacin (Levaquin)
Minocycline (Minocin)
Sulfamethoxazole and trimethoprim (Bactrim, Septra)
Tetracycline (Sumycin)
Antiviral Agents
Delavirdine (Rescriptor)
Foscarnet (Foscavir)
Lamivudine (Epivir)
Nevirapine (Viramune)
Zidovudine, AZT (Retrovir)
Zidovudine and Lamivudine (Combivir)
Blood Pressure Drugs
Hydralazine (Apresoline)

ACE inhibitors:

Enalapril and HCTZ (Vaseretic)

Angiotensin II receptor blockers:

Valsartan and HCTZ (Diovan HCT)

Diuretics, loop:

Bumetanide (Bumex)
Ethacrynic acid (Edecrin)
Furosemide (Lasix)
Torsemide (Demadex)

Diuretics, thiazide (and any combination drug that contains HCTZ or hydrochlorothiazide—dozens of drugs contain this)

Candesartan and HCTZ (Atac
and HCT)
Chlorothiazide (Diuril)
Chlorthalidone (Hygroton)
Hydrochlorothiazide or HCTZ (Hydrodiuril)
Methyclothiazide (Enduron)
Metolazone (Zaroxolyn)

Diuretics, potassium-sparing:

Possibly the potassium-sparing diuretics, however this is not conclusive

Diuretics, sulfonamide:

Indapamide (Lozol)
Cardiac Glycoside
Digoxin (Digitek, Lanoxicaps, Lanoxin)

Central Nervous System (CNS) StimulantsMethylphenidate (Metadate, Ritalin)

Cholesterol Agents
Cholestyramine (Questran)
Colestipol (Colestid)

Corticosteroids
Betamethasone (Diprolene, Luxiq)
Dexamethasone (Decadron)
Hydrocortisone (Cortef)
Methylprednisolone (Medrol)
Mometasone (Elocon)
Prednisolone (Pediapred Liquid)
Prednisone (Deltasone, Liquid Pred, Sterapred)
Triamcinolone (Aristocort cream)

Inhaled corticosteroids:

Flunisolide (Nasarel, Nasalide)
Futicasone (Flonase)
Triamcinolone (Azmacort inhaler)

Hormone Replacement Therapy / Oral Contraceptives
Diethylstilbestrol (DES)
Estradiol (Activella, Climara, Combipatch, Estrace, Estraderm, Estring, EstroGel, Femring, Menostar, and many others)
Estrogen-containing drugs (hormone replacement therapy and birth control)
Estrogens, conjugated (Premphase, Prempro)
Estrogens, esterified (Estratab)
Estropipate (Ogen)
Ethinyl estradiol (found in many birth control pills)
Levonorgstrel (found in many birth control pills)

Immunosuppressants

Cyclosporine (Sandimmune, Neoral)
Tacrolimus (Prograf)

Nonsteroidal Aromatase Inhibitors

Anastrozole (Arimidex)

Osteoporosis

Raloxifene (Evista)

SERMs (Selective Estrogen Receptor Modulators)
Raloxifene (Evista)
Tamoxifen (Nolvadex)
Toremifene (Fareston)

Sulfonamides Sulfa antibiotics, some diabetic medications

MISC:
Alcohol Calcium supplementation (prolonged or in excess)
Coffee
Estrogen dominance
High cortisol levels
High-sugar diet (glucose, fructose, sucrose)
Malabsorption of any sort (celiac or Crohn’s disease, pancreatitis, crash dieting, anorexia)
Mineral oil

For general drug mugging replenishment, I usually just say 300 - 400 mg once or twice daily. *

Tests used to determine mag levels are either RBC mag levels (blood draw) or something like a NutrEval by Genova, or Spectracell analysis or Metametrix (your practitioners will know what this is).

With your product [Jigsaw Magnesium w/SRT], since it has malic acid, it is great for people with muscle pain too, and I like the dose of 2 tabs twice a day. *But with MD approval, I think you could even higher. *The only problem with too much mag is that it tilts the sister minerals out of balance, and after chronic ingestion of high mag dosing, you could see a relative deficiency in other minerals like calcium, zinc, etc



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Last edited:
I take my magnesium and D3 every night before bed. It is so inexpensive why not? And given the fact that over 50% ( I think it is closer to 70%) of Americans are deficient in magnesium and D3, I would have everyone supplement it.
 
often times the blood test is only testing for the magnesium in the blood only. this can be at a normal level, while a person is still deficit at the cellular level.
 
I take 500mg of magnesium oxide per night!! It's not very absorbable but it helps with stomach issues and keeping me regular... and adds magnesium. I have citrate as well but only use 100mg of that one if not regular with oxicide..

Yes d3 too, folate acid..
I have a bunch of vits and minerals I use..

Magnesium had messed with my iron in past with phlebotomy's but maybe it was just phlebotomy's!!!
 
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