I am sure that, at one point in life, most of us have wished to decode our entire genome and know about hidden mysteries of ourselves that we otherwise wouldn’t really know!


Our whole genome is constituted by DNA and chromosomes in a very fascinating way.


The genetic traits that one possesses are deeply engraved in our entire genome and understanding the whole genome sequencing of self means one could explain why we behave the way we behave.


For those of you who are wondering about what exactly is genomic sequencing, it is basically a process used to decrypt the entire genetic makeup of a specific organism.


One of the most important reasons why people opt for genomic sequencing is because this process helps in knowing about one’s ancestry, distant relatives, and family history.


Because this method interprets the entire DNA sequence of an organism at one time, it is really helpful in identifying any mutations and correcting them timely!


While getting your whole genome sequencing test is not so common practice, it has gained some popularity in recent times owing to an increase in awareness as well as after the COVID-19 pandemic when many of us had lost our closed ones.


Importantly, with the rising prevalence of diseases especially different types of cancer, one really wants to know if he is genetically healthy.


Getting the right service for your whole genome sequencing is one of the critical steps because not only do you want accurate results but you will be providing your sensitive information in the form of genetic data for which you need data protection assurance as well!


This article is Nebula genomics review, one of the trusted and famous DNA testing services that we ourselves had used at Muscle and Brawn.


This honest yet detailed review will help you decide whether you need to choose Nebula genomics for your genome sequencing or go for any other alternatives.


Our Experience with Nebula Genomics
The sample collection kit that we ordered cost $100+, and we immediately sent back the kit with sample to their office alongside taking multiple online surveys related to different domains of life, such as Health, Sleep, Medications, Alcohol consumption, and any family history of rare diseases, and lifestyle factors.


The results took around 6 months to come out which was exceptionally longer than we expected.


Nonetheless, we received an extremely detailed report which highlighted almost any health condition that one could experience and suggested possible chances (calculated in percentile) that the subject could suffer from that medical condition.


For example, the team member at Muscle and Brawn that used the kit was more susceptible to experiencing Primary Biliary Cholangitis based on the study of 57 different genetic variants. On the other hand, there was just a 13% percentile chance that he could suffer from a Lacunar stroke.


In this way, we received 284 different reports based on different common and rare medical conditions. Perhaps the kit that we ordered also now gives us a lifetime subscription to the genetic library.


It also highlighted the possible ancestral linkage based on different regions of the world as well as genetic traits, such as appearance, behavior, body, nutrition, etc.


All in all, we had a pretty decent experience with Nebula genomics and as a highly accurate DNA testing company, we would recommend it to our readers for their DNA analysis.


Who Are Nebula Genomics?

Nebula genomics holds a high reputation amongst the other DNA testing companies primarily because of its founder George Church, who is a Professor of Genetics at Harvard Medical School and Professor of Health Sciences and Technology at Harvard University and the Massachusetts Institute of Technology (MIT).


The inquisitive mind of Professor George Church in the field of DNA sequencing led him to contribute to over 550 publications in high impact factor journals, and he had also written a book titled “Regenesis: How Synthetic Biology Will Reinvent Nature and Ourselves”.


His critical role in developing genome engineering technologies and also initiating a personal genome sequencing project helped him add multiple prestigious awards to his bucket.


Because of the pioneering work of Professor George Church in DNA sequencing methods, what he wants basically is to provide people with affordable yet quality whole genome sequencing.


The mission of Nebula Genomics is to understand Human Genomes and possibly assess as well as edit them, and for that reason, the laboratories of Professor George Church continuously work towards devising gene analysis tool and ways to edit the genome sequenced.


How Does Nebula Genomics Work?

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As you choose any of your desirable plans, you will be sent a sample collection kit to your address.


You will be required to send the collected sample kit back to them after which experts at Nebula genomics will decode your DNA data as well as genomic data and upload the results on your online portal.


Besides the collected sample, Nebula genomics also takes into account the multifactorial inheritance, and thus you are also asked to take 5-10 surveys which constitute dozen of questions for more accurate results.


Nebula genomics adopts the most up-to-date ways for whole genome sequencing, such as Next-Generation Sequencing (NGS) and long-read nanopore sequencing. These innovative methods allow the large sequencing of many short DNA fragments at the same time.


Not only do they integrate the latest technology for whole genome DNA sequencing, their laboratories religiously follow the phrase “prevention is better than cure”, and for that reason, they monitor personalized gene therapies to understand the etiology of genetic diseases so that a timely cure is possible.


Perhaps if you are already a subscription member of Nebula genomics, you will receive weekly updated DNA reports, reviews of different DNA tests, and importantly the science used behind human genetics and other possible health-related domains.


Best Nebula Genomics Products
At the moment, Nebula genomics offers 3 whole-genome sequencing packages, which are:

[*]Basic[*]Deep[*]Ultra Deep
Now let’s talk about the individual packages and see which one offers the most detailed analysis!



If you choose the basic package, it will decode only the important parts of your DNA with a DNA sequencing depth of 0.4x, and since it will test only the essential fragments of your autosomal DNA, all you would know from the test report is your ancestry analysis as well as any risk of developing genetic diseases.


One should know that accuracy of the basic DNA test kit is Medium, thus it only costs you $99 at the moment.


Talking about the most chosen package by the customers which is Deep, it will decode 100% of your DNA with a depth of 30x whole genome sequencing. It not only just analyzes fragments of autosomal DNA but the entire 20,000 genes, which includes the Y chromosome and mitochondrial DNA, thus providing you with valuable information regarding any possible rare genetic predispositions alongside the common ones.


The Deep package not only gives you high accuracy in gene analysis but also provides you with genome exploration tools for just $299.


Last but not least, the premium Ultra Deep package offered by Nebula genomics is the most accurate DNA test available in the market. It decodes your entire genome with ultra-high accuracy with a sequencing depth of 100x. This ultra deep test offers extremely comprehensive and accurate DNA test reports.


Besides decoding all 20,000 genes, it identifies any rare genetic health predispositions and provides access to gene exploration tools at a price of $999.


Although the price points of these 3 packages may differ, you would still be given access to privacy-preserving technologies which will keep your genetic data safe and secure.


Ordering and Shipping
Once you decide on your personal plan, all you need to do is pay via any of the acceptable modes, such as google pay, PayPal, or Visa card.


Choose your country at the time of checkout, and Nebula genomics will ship their sample collection kits to your address.


Once you send back the kit, all you need to do is wait till your entire genome is decoded and the results are uploaded on the website.


Customer Reviews
It is important to know what people have to say about the whole genome sequencing service offered by Nebula genomics because it might help you make a decision for yourself.


Kristy was impressed by the customer service of Nebula genomics and said,


“Being able to download all of your DNA, and venture off on a journey of exploration is truly incredible. And the constantly updated feed of new studies is extremely interesting.”


Paul found Nebula genomics really affordable and stated,


“A full genome test for a very affordable price. I am very happy with the quality of results and delivery time, even during the pandemic.”


Perhaps what Roberto found interesting was how Nebula genomics work towards extremely minor details. He left a review,


“I have been a user of sequencing services for the last 7 years. I have tried and tested pretty much all the companies in the market, and no one gets even close to the amount of information Nebula gives you.”


However, users did complain about receiving their test results extremely late which was also the case with us as we received them after 6 months. The other less frequent complaint by people is that test reports are a bit difficult to comprehend as well as extract useful information from.


Overall Nebula genomics seems to lie on the top with many satisfied customers and highly modern and latest technology in their laboratories.


Nebula Genomics Promo Codes
Not to forget, there is an ongoing 60% spring sale on whole genome sequencing.


Order your kit before the discount expires and know more about yourself at the cheapest of rates!


Alternatives to Nebula Genomics
Now let’s look at some of the alternatives to Nebula genomics that you can possibly opt for your genetic sequencing and see if they are any better!


Nebula Genomics vs Circle DNA
Unlike Nebula Genomics which offers only 3 packages, Circle DNA offers a wide array of options at different price points.


If you only want the test reports to revolve around your lifestyle, health, and wellness, you can choose the most low-tier Vital DNA test.


The other more expensive option is the Health DNA test which includes comprehensive test reports surrounding cancer and other common as well as rare genetic predisposition to mutations.


If you want a genetic analysis before starting your family, a Family planning DNA test should be your go-to option because it not only just analyzes your family tree DNA but also provides individual reports on specific genetic conditions which can be inherited by your offspring, such as Cystic fibrosis, Gracile Syndrome, etc.


The last option is buying a Premium DNA test which integrates all of the individual packages listed above. You will also be invited to genetic counseling sessions with lifetime access to genomic research updates.


Nebula Genomics vs 23AndMe
23AndMe is possibly best known for ancestry testing as it provides in-depth guidance on your ancestry and tells you about the diverse ethnicities that you may belong to.


23AndMe offers 2 services at the moment, which are basic and essential at different prices.


The basic package offers Ancestry testing as well as information on traits. They test the Y chromosome and mitochondrial DNA, thus accurately carrying out ancestry testing. Traits that this kit tells about are usually physical features, etc.


The other kit that 23AndMe offers information on health and Ancestry. Because multifactorial inheritance plays a critical role in developing conditions, such as breast and ovarian cancer, type 2 diabetes, and other mental disorders, such as Parkinson’s disease, they have partnered with FDA to release extensive reports on these conditions.


Despite their partnership with FDA, 23AndMe has continuously faced the complaint of being not that accurate in providing health reports.


Nebula Genomics vs Dante Labs
Dante Labs is an Italian company that offers two different tests for its customers.


The first test includes 30x whole genome sequencing within just 8 weeks and tells you about your DNA health, any genetic predispositions, and lifestyle as well as nutritional information based on your DNA analysis.


The other option that you can go for is Whole GenomeZ – Whole genome sequencing for Advanced analysis which provides 130x sequencing depth of your exomes, which are protein-coding regions of your DNA. This test kit offers a detailed analysis of any rare genetic mutations that you may possibly suffer from.


What is the Best Genomics Company?
This question is a bit subjective as one may have personal likings and dislikings.


Each company offers something unique in terms of its test kit, for example, 23AndMe is well-known for its ancestry testing while Circle DNA provides accurate information prior to your family planning and tells you about possible risk factors.


On the other hand, Nebula genomics proposes a complete plate as other DNA testing companies only decode 0.02% of DNA while Nebula genomics decodes 100% of your DNA. Other companies sell your DNA data and have no genetic exploration tools and don’t really provide weekly DNA reports.


While this is not the case with Nebula genomics as it gives you full ownership of your genetic data and updates you very frequently with new research.


In my opinion, with the pioneering work of Professor George Church, Nebula genomics leads the table as one of the best DNA testing companies.


How Expensive is Genome Sequencing?
The expected cost for whole genome sequencing can vary depending on how much you care about precise details.


It can go as low as $299 to as high as thousands of dollars.


If you choose any DNA testing companies that decode your genome, analyze it, interpret it, and offer you guidance from expert genetic counselors, your bill may sky-rocket! You will have to see your budget as well as the packages offered by your favorite service and then choose accordingly!


Is Nebula Genomics trustworthy?
Nebula genomics strongly believes in protecting your genetic data and they constantly update their privacy features to keep your genetic data safe and secure.


As one of the purpose-driven cum privacy-focused DNA testing companies, Nebula genomics has partnered with Oasis Labs which enables you to use cutting-edge privacy technology so that you have complete authority over your genomic data.


Not only this, but you can also adopt track usage with a Block-chain backed log feature which will keep you aware of how your genomic data is being accessed.


Does Nebula Genomics Sell your Data?
No!


Unlike other DNA testing services, Nebula Genomics is amongst the only few companies that believe in giving its customer full authority over their genomic data.


You can choose whatever you want to do with your genomic data and access it anytime and every time!


How Long Does Nebula Genomics Take?
Based on their timeline, you are expected to receive the sample collection kit approximately 2 weeks after ordering.


Once they receive your sample back, it is expected to take 12 to 14 weeks for your whole genome sequencing test.


While this may be the tentative timeline, one of the common complaints against Nebula genomics is the long duration that they take. Our experience was also somewhat similar as said earlier because it took 6 months for the test reports to come out.


Is Nebula Genomics CLIA certified?
Yes, it is.


Nebula Genomics is Clinical Laboratory Improvement Amendments (CLIA) certified. This has eventually resulted in better and quicker results in affordable prices for customers.


Where is Nebula Genomics Located?
The offices of Nebula genomics are located in San Fransisco and Boston. Thus, you need to send the sample collection kit back to their offices after which your genome will be decoded.


How does Nebula Genomics Make Money?
The primary source of income for Nebula genomics is by selling the 3 whole genome sequencing packages. The price range of the DNA testing packages is $99 for a basic, $299 for deep, and $999 for ultra deep.


Perhaps it also partners with many experienced researchers, genetics’ experts, and renowned institutions. Their laboratories also work towards developing gene exploration tools as well as gene analysis tools, and they play a pivotal role in ongoing research in genetic collaborations.





Is whole genome sequencing worth it?
The answer to this is a bit subjective!


If you are someone who has a strong family history of genetic health risks, then whole genome sequencing might be worth it because it may give a better action plan to mitigate any onset of genetic diseases.





What are the disadvantages of genome sequencing?
Perhaps there is no harm to one’s own health by performing genome sequencing.


Possible drawbacks include a lack of understanding of actual test reports as well as time constraints between submitting the test sample kit and the results updated.





Which DNA test is best for health?
Perhaps amongst all the DNA testing companies, Nebula genomics’ ultra deep package tops the list because not just only does it analyzes all 20,000 genes, which includes autosomal DNA, Y chromosome, and mitochondrial DNA, but also with ultra high accuracy and sequencing depth of 100x.


It actually tells you any risk of developing common as well as rare genetic diseases.





How long does it take to map a human genome?
The duration varies from company to company.


The first human genome project took 13 years to complete, but with modern technology available now, it takes 1 to 2 months to process.





Is Circle DNA accurate?
Circle DNA claims 99.9% accuracy, which is also validated by the Croucher lab of genomics.





How accurate is CRI genetics?
While CRI genetics claim 99.9% accuracy as well, the reviews of CRI genetics are a bit mixed.








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