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View Full Version : MGFand other products at the cutting edge.



Irishmuscle
04-13-2005, 09:57 AM
Have to say you guys seem very advanced on the drug aspect of bodybuilding on this forum. Have only just heard about IGF-1LR3 and as I read through this site there are a lot of other new drugs which sound even better. I don't plan on trying them out yet but always like to gather info for the old in depth chat in the gym. One thing which I can't find much about is MGF, I done a search and it gets a few mentions but not seen much actual info on how it works or what it does. Does it have another name or is there just very little info so far?
I really want to move away from heavy testosterone into more anabolic drugs as I don't like the sides from test. Have used GH and felt great on it and even slin goes down a treat with me. Am now looking forward to my first course of IGF after a good break from the gear and an all clear from my doctor regarding blood tests. Any info graciously received.

saudades
04-13-2005, 07:12 PM
Here is a little bit of info regarding MGF:

http://politics.slate.msn.com/id/2079406/

The company that has been able to make MGF, according to this article, has kept a tight rein on it which is why it is not available like IGF is now. From the material I've read about MGF, it would seem to be better to use than IGF.

I've used IGF myself (the lr3-IGF from MC), and it has been wonderful.

Marble
04-14-2005, 12:09 AM
mgf is just another name for a particular form of igf-i, a flavour of igf-ie. your muscle splices the igf-i molecule to create this with exercise, and it causes different adaptation from igf-i's standard response. this is nothing novel.

i also have to warn people about il-15; don't take this drug lightly, particularly not with insulin. it's very potent at stimulating your immune system and may trigger an autoimmune attack on various systems, including your pancreas (type 1 diabetes and more likely when running slin).

Irishmuscle
04-14-2005, 11:12 AM
I thought MGF affects the myostating gene but IGF has a different mechanism of action, didn't realise they were the same.

Marble
04-14-2005, 11:18 AM
they aren't the same. mgf is a "flavour" of igf-i and your body will produce it from igf-i. it'd be like taking DHT instead of testosterone -- yeehaw.

saudades
04-14-2005, 03:56 PM
MGF doesn't affect the myostatin gene. It is as Marble said--a flavour of IGF.

I did find info on MGF interesting, however, because I believe I remember reading in an earlier post, Marble said that exercise doesn't upregulate IGF--but in some of the research I read, exercise does upregulate MGF. That is an important difference IMO.

Marble
04-14-2005, 04:14 PM
very true, tony. exercise increases the amount of igf-i that is cleaved into mgf. it doesn't upregulate your igf-i receptors.

if you work out, direct mgf supplementation rather than igf-i supplementation would probably be worse since you miss out on a lot of igf-i's other benefits. if you don't, why are you here? and what's the effect of increased mgf production without any microtears to repair? well, who knows.

saudades
04-14-2005, 05:32 PM
Well, Goldspink's experiments did work with mice, but that doesn't mean it will neccessarily work with humans.

Though I thought that MGF seemed better than IGF, I guess it would be a waste of money for those of us who are trying to build up through exercise. Our money would be better spent getting IGF instead. I'd rather get all the extra benefits of IGF than mess around with MGF. (And that, of course, is why we have sites like MC and knowledgeable people on them to educate us.)

Thanks for the info, Marble!

Irishmuscle
04-15-2005, 09:10 AM
Thanks for the info guys, it was all starting to get a little confusing.