Egrifta

MitchMiller

New member
Anyone using Egrifta? Basically it increases HGH. I've read on other forums that it really works as well as, if not better than, serostim.

From the manufacturer's web site:

EGRIFTA® is an injectable prescription medicine to reduce the excess in abdominal fat in HIV-infected patients with lipodystrophy. EGRIFTA® contains a growth hormone-releasing factor (GRF).
 
Hmm I just looked it up, and it sounds like an old product called "Lipostabil" that you would inject subcutaneously into the abdomens fatty area. Not sure if the ingredients are even remotely close, but i did find this info below about "Egrifta".

I am curious why this is only for HIV patients?? Why isnt it sold and used for non HIV positive people who could use the help melting the fatty areas and fat pockets. Maybe this is part of their test phase before it goes mainstream. I know that sounds cynical of me to think they would do something so fucked up, but what better testing group of people are there other then those on their way out anyhow from HIV.

Sorry im prolly way off here, but im real curious why this is for HIV positive people only, it doesnt make any sense to me at all!!

Why Talk With Your Healthcare Provider About Your HIV-Related Excess Belly Fat?
Because if it’s bothering you, it’s worth talking about.
And because there’s EGRIFTA®. The first FDA-approved medicine shown to reduce HIV-related excess belly fat.

EGRIFTA® is an injectable prescription medicine to reduce the excess in abdominal fat in HIV-infected patients with lipodystrophy. EGRIFTA® contains a growth hormone-releasing factor (GRF).


•The impact and safety of EGRIFTA® on cardiovascular health has not been studied.
•EGRIFTA® is not indicated for weight loss management.
•It is not known whether taking EGRIFTA® helps improve compliance with anti-retroviral medications.
•It is not known if EGRIFTA® is safe and effective in children. EGRIFTA® is not recommended to be used in children.
Ask your healthcare provider for more information about EGRIFTA®. If you have been prescribed EGRIFTA® and have questions about product support, please call the AXIS Center toll-free at 877-714-AXIS (2947).



EGRIFTA® (eh-GRIF-tuh)
(tesamorelin for injection) for subcutaneous use

Do not use EGRIFTA® if you:
•have pituitary gland tumor, pituitary gland surgery or other problems related to your pituitary gland
•have or had a history of active cancer (either newly diagnosed or recurrent)
•are allergic to tesamorelin or any of the ingredients in EGRIFTA® (mannitol or sterile water)
•are pregnant or become pregnant. If you become pregnant, stop using EGRIFTA® and talk with your healthcare provider.
Before using EGRIFTA®, tell your healthcare provider if you:
•have or have had cancer
•have diabetes
•are breastfeeding or plan to breastfeed. It is not known if EGRIFTA® passes into your breast milk. The Centers for Disease Control and Prevention (CDC) recommends that HIV-infected mothers not breastfeed to avoid the risk of passing HIV infection to your baby. Talk with your healthcare provider about the best way to feed your baby if you are taking EGRIFTA®
•have kidney or liver problems
•have any other medical condition.
Tell your healthcare provider about all the medicines you take, including prescription and non-prescription medicines, vitamins, and herbal supplements. EGRIFTA® may affect the way other medicines work, and other medicines may affect how EGRIFTA® works.

How should I use EGRIFTA®?
•Read the detailed "Instructions for Use" that comes with EGRIFTA® before you start using EGRIFTA®. Your healthcare provider will show you how to inject EGRIFTA®.
•Use EGRIFTA® exactly as prescribed by your healthcare provider.
•Inject EGRIFTA® under the skin (subcutaneously) of your stomach area (abdomen).
•Change (rotate) the injection site on your stomach area (abdomen) with each dose. Do not inject EGRIFTA® into scar tissue, bruises or your navel.
•Do not share needles or syringes with other people. Sharing of needles can result in the transmission of infectious diseases, such as HIV.
EGRIFTA® may cause serious side effects including:
•Serious allergic reaction. Some people taking EGRIFTA® may have an allergic reaction.

Stop using EGRIFTA® and get emergency help right away if you have any of the following symptoms:
◦a rash over your body
◦hives
◦swelling of your face or throat
◦shortness of breath or trouble breathing
◦fast heartbeat
◦feeling of faintness or fainting
•Swelling (fluid retention). EGRIFTA® can cause swelling in some parts of your body. Call your healthcare provider if you have an increase in joint pain, or pain or numbness in your hands or wrist (carpal tunnel syndrome).
•Increase in glucose (blood sugar) intolerance and diabetes. Your healthcare provider will measure your blood sugar periodically.
•Injection site reactions. Change (rotate) your injection site to help lower your risk for injection site reactions. Call your healthcare provider for medical advice if you have the following symptoms around the area of the injection site:
◦redness
◦itching
◦pain
◦irritation
◦bleeding
◦rash
◦swelling
The most common side effects of EGRIFTA® include:
•joint pain
•pain in legs and arms
•swelling in your legs
•muscle soreness
•tingling, numbness and pricking
•nausea
•vomiting
•rash
•itching
These are not all the possible side effects of EGRIFTA®. For more information, ask your healthcare provider or pharmacist.

Tell your healthcare provider if you have any side effect that bothers you or that does not go away.

Call your doctor for medical advice about side effects. To report side effects, contact EMD Serono toll-free at 1-800-283-8088 ext. 5563. You may report side effects to FDA at 1-800-FDA-1088.

Use:
•EGRIFTA® is an injectable prescription medicine to reduce the excess in abdominal fat in HIV-infected patients with lipodystrophy. EGRIFTA® contains a growth hormone-releasing factor (GRF).
•The impact and safety of EGRIFTA® on cardiovascular health has not been studied.
•EGRIFTA® is not indicated for weight loss management.
•It is not known whether taking EGRIFTA® helps improve compliance with anti-retroviral medications.
•It is not known if EGRIFTA® is safe and effective in children. EGRIFTA® is not recommended to be used in children.
If you would like more information, talk with your healthcare provider. You can ask your healthcare provider or pharmacist for information about EGRIFTA® that is written for healthcare professionals.
 
Interesting find. I have no idea what would be different about fat deposits in an HIV patient from someone without. If it proves to be an effective method of removing stubborn belly fat then I'm in. I've got two pockects of rear love handle (back fat) that won't budge even when my bf is in the 6-8% range.
 
Interesting find. I have no idea what would be different about fat deposits in an HIV patient from someone without. If it proves to be an effective method of removing stubborn belly fat then I'm in. I've got two pockects of rear love handle (back fat) that won't budge even when my bf is in the 6-8% range.

exactly? im thinking maybe they are just testing it out on this group of people first? lol, seriously though anyone know what the difference would be?
 
This product is used to cause the body to increase production of HGH. So instead of injecting the HGH directly, you inject the catalyst that causes the body to produce it. That results in a much more stable level of HGH, instead of levels shooting up for a couple hours after injecting HGH directly.

I doubt that the FDA would approve HGH or, in this case, an HGH catalyst, as a "lifestyle" drug. Otherwise, HGH producers would have gone that route years ago. It's well documented that HGH reduces body fat when accompanied with exercise. Therefore, the only legitimate market for this drug would be to target something like HIV lipo. Remember the manufacturers of Serostim took the same route to get rapid approval by targeting HIV patients, in that case, to gain muscle mass.

There is a difference between HIV lipo fat and what is known as adipose fat. The lipo fat is internal, around the organs, and hard. It is inoperable (cannot be removed by liposuction without damaging organs). However, the point is that this class of drugs is better than injecting HGH directly. If HGH is known to work on adipose fat, this drug would work better.

FYI, another company (AEZS) has an HGH catalyst (AEZS-130) that should be on the market in a year. The route they are taking to get FDA approval is to target the drug as a diagnostic test. That should provide a means to get FDA approval. They have also started a trial (or will be) to use the drug to help cancer patients gain muscle mass (note this is nearly the same path taken for Egrifta).

I'm expecting that eventually lookalikes will eventually hit the black market and could replace HGH altogether as a body building supplement.
 
Interesting find. I have no idea what would be different about fat deposits in an HIV patient from someone without. If it proves to be an effective method of removing stubborn belly fat then I'm in. I've got two pockects of rear love handle (back fat) that won't budge even when my bf is in the 6-8% range.

This isn't related to the topic here, but in order to target back fat loss, you need to hit a heavy bag bro. The sudden stopping of the body as you hit the heavy bag hits that specific area so it's great for shedding fat in that exact spot. Mainly left and right hooks are the best for this, but just start out mixing it up with jabs, hooks and all of that. You should start to see a difference
 
This product is used to cause the body to increase production of HGH. So instead of injecting the HGH directly, you inject the catalyst that causes the body to produce it. That results in a much more stable level of HGH, instead of levels shooting up for a couple hours after injecting HGH directly.

I doubt that the FDA would approve HGH or, in this case, an HGH catalyst, as a "lifestyle" drug. Otherwise, HGH producers would have gone that route years ago. It's well documented that HGH reduces body fat when accompanied with exercise. Therefore, the only legitimate market for this drug would be to target something like HIV lipo. Remember the manufacturers of Serostim took the same route to get rapid approval by targeting HIV patients, in that case, to gain muscle mass.

There is a difference between HIV lipo fat and what is known as adipose fat. The lipo fat is internal, around the organs, and hard. It is inoperable (cannot be removed by liposuction without damaging organs). However, the point is that this class of drugs is better than injecting HGH directly. If HGH is known to work on adipose fat, this drug would work better.FYI, another company (AEZS) has an HGH catalyst (AEZS-130) that should be on the market in a year. The route they are taking to get FDA approval is to target the drug as a diagnostic test. That should provide a means to get FDA approval. They have also started a trial (or will be) to use the drug to help cancer patients gain muscle mass (note this is nearly the same path taken for Egrifta).

I'm expecting that eventually lookalikes will eventually hit the black market and could replace HGH altogether as a body building supplement.

Exactly what i was asking and what I did not understand, thanks brutha, great post!!!
 
GRF's and GHRH's fundamentally can not be more effective than exogenous GH, the same as testosterone boosters, metformin, or taking T4 will never trump injectable testosterone, insulin or T3. The body strives for homeostasis via the negative biofeedback loop. If the body plays ANY part in producing supraphysiological amounts of any hormone, it will eventually attenuate and once again drop to its normal output. It is inevitable and proven over and over. It is what it is. The golden egg is already out there. All of these other products are simply trying to take a sliver of the market share by taking aim at the uneducated and desperate. Besides, how is a GHRF which has to signal the pituitary to produce GH going to be spot effective??!! To make such claims is insulting to anyone with a fundamental knowledge of human biology.
 
This isn't related to the topic here, but in order to target back fat loss, you need to hit a heavy bag bro. The sudden stopping of the body as you hit the heavy bag hits that specific area so it's great for shedding fat in that exact spot. Mainly left and right hooks are the best for this, but just start out mixing it up with jabs, hooks and all of that. You should start to see a difference


I'm no stranger to heavy bag work so I'll give it a shot! Thanks for the tip! Should be fun because my aggression is through the roof right now! lol
 
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