Kynoselen® non-steroidal anabolic agent detailed profile , history and administration

akn · May 29, 2014

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Kynoselen is an injectable veterinary drug, currently
produced by the international firm Vetoquinol. It contains a
mixture of heptaminol, AMP (adenosine monophosphate),
vitamin B-12, sodium selenite, magnesium aspartate, and
potassium aspartate. This blend makes for a restorative
“tonic” type drug, administered to protect an animal’s muscle
mass and overall wellness after illness, injury, or trauma. It
is most often used on horses, and is typically applied as an
anti-catabolic after strenuous activity, or to help get an
animal back on its feet after a debilitating infection/illness.
At other times it is simply used to support the vitality of an
animal that is otherwise healthy, but at the moment less than
vigorous in its daily activities. In some cases it is even used
for the very basic purpose of remedying a deficiency in
vitamin B-12 or selenium intake. Bodybuilders are attracted
to Kynoselen for its mild anabolic and lipolytic properties.
The principle active ingredient in Kynoselen is heptaminol,
which is classified as an amino alcohol with myocardial
stimulant and vasodilatory properties. It is also identified as
an inotropic compound, which increases contractile strength
and minimizes fatigue, of skeletal muscles.640 It has
demonstrated a specific ability to increase the differentiation
of satellite muscle cells,641 a process that helps generate new
muscle tissue (skeletal muscle growth). This same ingredient
is also known to affect the release and uptake of
norepinephrine (noradrenalin), increasing levels of this
hormone/neurotransmitter in the blood.642 Since noradrenalin
is an important regulator of lipolysis in humans, this allows
heptaminol to impart some fat-loss effect. Adenosine
triphosphate is also regarded as a key component of the
product, and plays a role in the storage and release of energy.
Overall, both the anabolic and lipolytic properties of
Kynoselen are measurable when used in humans, but not
dramatic. It is capable of imparting some increases in
strength, muscle mass, and fat loss, but the results will not
rival those of anabolic steroids. Still, being that this drug is
legal in most jurisdictions, it remains an attractive alternative
to anabolic steroids for many individuals.
History:
Heptaminol, the principle active ingredient in Kynoselen,
was first heavily investigated in clinical medicine during the
early 1950s. It was soon developed into a prescription drug,
and has since been sold by a series of drug manufacturers in
many different parts of the world. Currently its most common
therapeutic use is to treat orthostatic hypotension, which is a
sudden drop in blood pressure upon standing. Various
preparations containing heptaminol have been produced over
the years, the most notable of which have included Amidrina
(Italy), Cortensor (Belgium and Switzerland), Hept-A-Myl
(USA), Heptamyl (Belgium and Switzerland), and Heptylon
(France). Although a variety of human medications
containing heptaminol have been in commerce for decades,
these preparations were rarely of interest to athletes. Years
later, under a far different medical setting, Western athletes
were first introduced to the drug.
The French veterinary preparation Kynoselen would be the
first heptaminol-containing drug to grab large-scale
international attention, becoming popular among American
bodybuilders and athletes during the latter part of the 1990s.
This was some years subsequent to laws being passed that
had increased the penalties for dealing in anabolic steroids.
During this time, availability of the drugs had shifted, and for
some buyers scarce supply and high legal risk made the drugs
less attractive. Many athletes were becoming increasingly
resourceful in finding other non-scheduled performanceenhancing
drugs that could be purchased and used with less
legal risk. Kynoselen was already known to athletes in
Europe, and would quickly cross the Atlantic. By the year
2000, a number of exporters had set up operation to market
the drug directly to American athletes. Today, Kynoselen
remains unscheduled and widely available in the United
States and many areas abroad.
How Supplied:
Kynoselen is most commonly supplied in a 100 mL multidose
vial for injection. Active ingredients are heptaminol,
disodic adenosine monophosphate, vitamin B12, selenium
(sodium selenite), magnesium aspartate, and potassium
aspartate.
Structural Characteristics:
Heptaminol (supplied as heptaminol hydrochloride) is an
amino alcohol with a structure of 6-amino-2-methylheptan-2-
ol.
Administration:
Kynoselen is not approved for use in humans. Prescribing
guidelines are unavailable. An effective dosage for
physique- or performance-enhancing purposes generally falls
in the range of 1 mL weekly for every 25 pounds of
bodyweight. This would mean that a 200lb bodybuilder
would use around 8 mL per week. Due to high injection
volume, some opt to take a lower dosage, injecting at the
very least a 2 mL three times per week. At this dose, a single
100 mL vial would last about 16 weeks. At 8-10 mL per
week a 100 mL bottle would last for 10 to 12 weeks. It is
generally recommended to use the entire bottle once it has
been opened, or discard any remaining drug that was not
used during the cycle. As with all injectable drugs packaged
in multi-dosed vials, contaminants will be introduced into the
solution immediately once the seal is broken for the first
injection.
Because it tends to increase noradrenalin levels, Kynoselen
is also a mild stimulant. It is likely for this specific reason
that its use has been banned by certain horseracing
organizations. This means that one can expect certain
stimulant-related side effects, especially when taking this
drug in higher dosages. This includes rapid heartbeat,
sweating, jitters, restlessness, increased blood pressure, or
insomnia. A good rule of thumb used by bodybuilders to try
and keep such side effects from becoming a problem is to
never inject more than 2 mL per day. They may also want to
start with an amount lower than the recommended dosage
(determined by bodyweight), perhaps even half of this. The
dose is then slowly increased, so that the peak level is
reached only after three to four weeks of slow incremental
increases.
Warnings:
Individuals with high blood pressure or cardiovascular
disease should not use Kynoselen
Availability:
Kynoselen usually sells for $75 to $100 per bottle at the
retail level. It is not a controlled substance in the United
States, and is likewise pretty easy to obtain locally or via
mail order. Currently no significant fakes are known to exist.
Given its abundance and low cost, counterfeits are not
expected to be a significant problem anytime soon. It is also
important to note that legitimate Kynoselen is a veterinary
drug only, and has never been manufactured for human use

By William Llewelyn

Buffalo · May 29, 2014

Good shit. Keno alone didn't seem to have much effect so stack it with injectable l-carnitine and works awesome. It's not a magic combo, you have to be pretty lean to see a difference.

Kynoselen® non-steroidal anabolic agent detailed profile , history and administration

akn

Musclechemistry Member

Buffalo

MuscleChemistry Member

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