Adipex-P® (phentermine hydrochloride) Fat Loss Agent profile and weight loss effects

akn · Jun 14, 2014

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Phentermine hydrochloride is a sympathomimetic stimulant
of the amphetamine family. Like other amphetamine
derivatives, it is categorized as an anorectic (appetite
suppressing) agent. Phentermine is commonly prescribed as a
weight loss aid in obese patients. It is typically used for short
periods of time (less than 12 weeks), and as an adjunct to
support an ongoing exercise and dieting regimen.The main
focus is to curb the desire to eat, thereby reducing the total
caloric intake. Although the data seems to vary from trial to
trial, much of it supports at least a modest additional loss of
fat mass with the use of phentermine hydrochloride.886
Athletes and bodybuilders use phentermine hydrochloride for
the same purpose, typically when weight loss is required for
physique remodeling or competition.
History:
Phentermine hydrochloride was first introduced to the U.S.
drug market in the 1970s. Base phentermine was available in
the U.S. as far back as 1959. Phentermine had long been used
as an appetite suppressant, although the most notable
attention to it came in the early 1990s, when the drug was
successfully paired with fenfluramine during diet studies.
Investigators had shown that this type of drug combination
was actually more effective at promoting weight loss than
diet and exercise, results that quickly catapulted Fen-Phen
into top place in the prescription weight loss drug market. By
1997, however, it had become apparent that a very high
percentage of Fen-Phen users were noticing heart valve
defects as a result of the drugs. Fenfluramine was identified
as the principle cause, and was withdrawn from the U.S.
market that same year. Phentermine remains available in the
U.S. and many nations abroad today. Popular trade names
include Adipex, Ionamin, Anoxine, Phentrol, and Obenix.
Note that as an amphetamine derivative, this medication has
a tendency to be habit forming. For this reason it has been
added to the U.S. controlled substances list as a schedule IV
medication.
How Supplied:
Phentermine hydrochloride is most commonly supplied in
tablets and capsules of 18.75 mg and 37.5 mg each.
Structural Characteristics:
Phentermine hydrochloride is a central stimulant and
indirect-acting sympathomimetic of the amphetamine family.
It has the chemical designation 2-methyl-1- phenylpropan-2-
amine (2-methyl-amphetamine).
Side Effects:
Common side effects associated with phentermine
hydrochloride include insomnia, increased blood pressure,
irritability, nervousness, and euphoria. Less common side
effects include vision disturbances, reduced libido,
confusion, diarrhea, dizziness, dry mouth, headache, irregular
heartbeat, nausea, vomiting, rash, and tiredness. Phentermine
is a CNS stimulant with potential for fatal overdose. Signs of
overdose may include rapid breathing, fever, hallucinations,
blood pressure irregularities, irregular heartbeat,
unconsciousness, trembling, shaking, panic, extreme
restlessness, and severe nausea, vomiting, or diarrhea.
Administration:
For optimal effectiveness, phentermine hydrochloride should
not be taken with food. The usual adult dose is one capsule
or tablet (37.5 mg) daily, administered before or 1- 2 hours
after breakfast. For some patients a half of a tablet (18.75
mg) daily may be adequate, while in other cases it may be
advisable to give a half of a tablet (18.75 mg) twice
daily.When taken more than once per day, the second dose
should never be taken within 4-6 hours of sleep. The drug is
typically used for 3-4 weeks at a time, with longer durations
of therapy rarely exceeding 12 weeks. Bodybuilders and
athletes typically use the prescribed amount of drug in a
similar short-term fashion,due to the high likelihood of side
effects as the dose escalates beyond the normal therapeutic
range.
Availability:
Phentermine hydrochloride is available in a number of
different countries. It is not widely counterfeited. U.S.
residents would not be advised to order the drug from
overseas, however, since phentermine is a schedule IV
controlled substance and carries similar legal restrictions as
Valium and anabolic steroids. Many U.S. doctors who
specialize in weight loss medications will readily dispense
phentermine for controlled periods of weight loss.

Adipex-P® (phentermine hydrochloride) Fat Loss Agent profile and weight loss effects

akn

Musclechemistry Member

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