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View Full Version : The beginners Guide to Anabolic Steroids in my own words-Please Read



Powderguy
02-17-2015, 10:58 AM
I am posting this with permission of the of the research Author. Ryan thank you for allowing me to post this with some information you have researched and even change things to allow for my own opinion and experiences of 15 years of anabolic Steroid use. Including my many years as a Biochemist working with various Pharma companies that mass produced Raws, Compounds and single dose substances. I have included some humor to help you get through the article but in the end I hope you learned something

Right off the bat, we’re going to make things clear about what this article is about if the Title itself didn't tell you. This is an article that will take a relatively uninformed individual- someone who has obviously heard about steroids and may have done some casual reading- and increase their level of knowledge dramatically and even been on the boards learning everyday. I will do my best to break this down Barney style and make sure you understand all my big words and what they mean. It will be a broad overview of the topic of steroids in general. If you’re looking for a an in-depth thesis with multiple references, dedicated to helping advanced users learn more, this isn’t going to be it. I can certainly cover more advanced topics in later articles, but my goal right now is to make sure that we’re all on the same page, or at least in the same book. Having said that, let’s get right down to it.

AAS, What are they and what do they do?
Anabolic-Androgenic Steroids (AAS) is a term used to describe testosterone or a derivative of testosterone that either occurs naturally or is produced in a lab. The “anabolic” part of the name refers to the ability of the hormone to cause muscular growth, while the “androgenic” part refers to the ability of the hormone to cause an increase in secondary sexual characteristics or masculinizing side effects (i.e. deepening of voice, hair growth, acme etc.). Many people will refer to a particular steroid as being more anabolic than androgenic or vice versa, but let’s keep in mind that they all have both characteristics, as the same receptors mediate both responses. We also like to talk about lots of different kinds of AAS, but they’re all very similar in one regard. They’re based on the same structure with some modifications added to affect various binding affinities, half-lives, etc. With a small change in chemical structure, we can see a very large change in what the hormone actually does. To illustrate this point, we see how very closely related plain androstenedione and estrogen are to the testosterone molecule. They are relatively the same but have one molecule of difference that distinguished their different characteristics. Now if you’re still truly unaware of what they do, we may have to have a little talk about taking some remedial reading classes. Obviously, people use AAS to increase muscle mass and decrease body fat. Of course, if you listen to many within the medical community, you’ll hear that it’s all the placebo effect and they don't really all do what they say. You should tell that to the largest Bodybuilder you can find and see if roid rage is true too! Okay, okay, we can be serious and get a little more into what AAS actually do on a practical and an academic level here. When used in a supra-physiologic (Greater than normally present in the body) dose, AAS cause a great deal of nitrogen retention, nervous system activation (to the point of insomnia for many users), increased strength, increased recovery, as well as the aforementioned increase in muscle mass and decrease in body fat.

How does all of this happen?
Well, we know some of it, and we just plead ignorance for now about other parts of it. The main actions of AAS seem to be mediated through the androgen receptor-remember we talked about this. Testosterone molecules either float free in your bloodstream or are bound to sex hormone binding globulin (or testosterone binding globulin). If they’re free, they diffuse across your cell membrane and directly bind to the androgen receptor (remember my water tray example?). If it’s bound, the entire complex enters the cell through a specific receptor mediated mechanism, then binds the androgen receptor. Once the androgen receptor is bound, it is ACTIVATED FULLY. Things aren’t done half-assed by certain molecules and better by others. This is an important concept to remember when we talk about how certain steroids work. Binding affinity is how long each molecule stays bound to the androgen receptor and activates it. This trait varies widely among such otherwise similar molecules. Once bound, the complex travels to the cell nucleus and promotes protein synthesis. I know this may be a bit confusing but I tried to break it down in the simplest terms I know how. If you have questions ask me.
There is also some research that seems to show us that AAS work through mechanisms other than the androgen receptor as well. Proposed mechanisms include reaction with glucocorticoid receptors, differentiation of muscle satellite cells into mature muscle cells, and a host of others that aren’t necessarily as well substantiated as of yet. For this reason, people often do their best to combine steroids that seem to work primarily through the androgen receptor with those who seem to exert their effects primarily through other mechanisms. Is this grounds for a black and white, two class system of categorizing steroids? My honest answer is that I don’t know just yet but it could be. From what I’ve seen, there seems to be a continuum of steroids from those that cause nearly all of their action through the androgen receptor and those that seem to act primarily by other mechanisms. The truth is probably that most act through a combination of the two. Time will tell and maybe I will write another article explaining that.

Who should use them?
Now I’m going to be a realist here, my friends. I realize that there is probably nothing that I can say that will convince you to either use or not use steroids. In fact, I’m not even going to try. What I can do is give you the information and my opinion about who would best benefit from use with minimal long term side effects and the safest group (age category, medical conditions ETC.). First of all, I don’t think that any teenager should ever touch a steroid. I’m sure you’ve all heard the line about how teenagers are a raging ball of hormones, blah, blah. Sure that’s true, and they have tremendous potential for natural growth with lots of food and hard training, but try telling that to a young kid who wants to get “swole”. So, we can appeal to their vain side. The truth is that AAS can cause a premature closure of the growth plate in long bones in anybody not fully physically mature. This is a proven fact in dwarfism! Look it up. Want to take steroids when you’re 15-21? Hope you like how tall you are now, buddy, cause that’s likely how tall you’re ever gonna be. On a more experienced and practical note, if you’re using before you have at least five or so years of training under your belt, how can you ever know what you’re capable of naturally? How will you ever learn to fine-tune your diet and training if you’ve always been assisted? Take the time to learn your body and how it responds to various things. Get near that magical natural limit or at least somewhere in the ballpark, THEN assist yourself in getting over that limit.

If you have not done blood work, GET IT DONE before you ever consider taking any AAS. This is something I wont beat around the bush at. You may have a issue that may kill you or harm you worse from taking AAS without ever knowing if your body is well enough. Here's a real look into it for ya, In High School I had a friend who insisted he wanted to take steroids. So, he did, about 8 weeks into it he passed out in the weight room and went into a coma. Later it was found he was a type 2 diabetic (controlled with diet)and never knew he turned into type 1 (needs insulin) by adding steroids and increasing his insulin sensitivity. He went into a diabetic coma, a simple blood test would have shown him this-he was 19 with no history of diabetes in his family. So think about it first and get the blood work done.
Again, I realize I’m probably not convincing anybody with their mind made up already, but you can’t say that I didn’t try. Also, it’s my opinion that you should be fairly lean before you embark on a cycle. Twelve percent bodyfat seems like a good number to start at. If you’re above that, then you need to diet down. Factual Research shows that overfeeding a lower starting bodyfat percentage leads to a greater percentage gain of lean mass than in those who start out with high bodyfat levels. If you’re going to make the effort to do a cycle, then why not get the most you possibly can out of it?

Orals vs. Injectables
Orals are a man’s best friend and we tend to like them from hot blondes. Oh wait, we’re still talking about steroids, aren’t we. Hmmm…Anyway, it’s pretty obvious that orals are the more convenient to take. The same reason that we can take some steroids orally is the reason that we tend to limit their use to short periods of time. The steroid is modified by adding an alkyl group to the 17th position on the steroid molecule. (I know to most of you this is a foreign language but learn it, as it may very well save your liver). Whenever we ingest something orally and it is absorbed by the GI tract, it must pass through the liver before it gets into the general circulation of the body. This alkylation of the steroid molecule allows the steroid to survive this pass through the liver and enter our general circulation. The unfortunate part of this is that these groups seem to impart some liver toxicity and stress the liver due to the steroid use. Invariably, after several weeks of oral steroid use, you will see a rise in your liver enzymes. They most often return to normal after the use is discontinued, but whether this is doing any permanent damage or not is still up for debate. Keeping this in mind, do you have to use orals? Absolutely not. Will you grow three heads and will your liver explode if you use orals? Nah, but don’t discount the possibility that long-term use of oral AAS could have the possibility of giving you long-term liver damage and it increases if you take aspirin, ibuprofen, alcohol and other meds that may stress the liver. The risk is probably overstated, but I’d rather be safe than sorry when it comes to my <o:pbody. Bottom line, keep your oral use to a relatively brief time. Six to eight weeks seems to work for most people. Now on to injectables. I know, you big sissy, that you want no part of sticking a needle in your silky smooth skin. Well, you’re just gonna have to get over that one. If you want to fully take advantage of AAS, you’re going to have to use injectables.</o<o:p
</o<o:pIn fact, many very good cycles are only injectable. After you get over the initial fear and just do it, you’ll be just fine with it and might even look forward to injecting like some sick puppy. Based on real world feedback, there are a lot of sick puppies out there! I won’t go over injectable steroids in too much detail as they’re pretty self explanatory. Briefly, you inject intramuscularly (NOT intravenously!) either an oil-based or water-based solution containing the steroid. Water-based are fairly short acting and need to be injected more frequently and most are uncomfortable. Oil-based are generally longer acting (although this doesn’t apply to all) and need to be injected less frequently as the oil tend to slow the absorption of the steroid. Other factors come into play, such as the half-life of the steroid itself, which is the time is takes for half of the steroid to disappear from the bloodstream. The shorter the half-life, the more frequently you have to inject to keep blood levels at a constant level. You would tend to think that injecting more frequently is simply a pain in the ass, no pun intended for you veteran users out there, and that a once-a-week injection would be preferable. Shorter acting steroids have the advantage of being cleared more rapidly, which is great for those who undergo scheduled drug testing or want to stop when they need to due to adverse affects, colds, injuries etc. Some people also claim to “feel” the steroid working more rapidly when using short acting versions. This may be psychological, but by my own experience there are some that can just kick your butt within a few hours of injecting them.
Injection technique
Since we’re in to being practical with our information and assuming that nobody knows anything about the steroid game, we can go over basic injection technique. If you want a great website that goes over this in even more detail than I will, please visit www.spotinjections.com. ( I have referenced this to many of you PM'ing me asking me questions) Transfer of the liquid from amp or vial to your syringe will depend on how your prize comes packaged. An amp can be opened by simply grabbing the top part and snapping it off. Some people like to use pre-made amp openers. Some use the cap of a ball point pen. You can use your fingers with a towel if you want. Just don’t cut yourself on the glass. Once you snap off the top, you can just suck out the liquid with your syringe, and you’re ready to go. This is more old school as most comes in multi-dosed vials now. If you’ve got a sealed multi-dosed vial with a rubber stopper, we have to do things as cleanly as possible, as we’re going to use the same vial repeatedly. The first thing to do is to clean the top of the vial with an alcohol wipe. Let it dry so your not just wetting the bacteria and stuff on top. Simple but effective. Next, we take the vial and turn it upside down with the rubber stopper facing the floor. Take your syringe with the needle on it and before you stick it in the vial, pull back the plunger to the number of cc’s that you want to inject. Now, with the vial still upside down, stick the needle through the rubber stopper. Push the plunger all the way in to inject air into the vial. This creates positive pressure in the vial that will allow the fluid to more easily flow into your syringe. This also tells you if your syringe is working fine and not waiting till you stick yourself to find out it isn't. Now, pull back the plunger to whatever amount you need and remove. This probably sounds more complicated than it really is, but you’ll get the hang of it pretty quickly. Quickly, clean vial, pull back, stick in, push in, pull back. (in the vial of course not yourself, that's coming up) Once you do it a few times, you won’t even think about it.

</o<o:p </o<o:pNow, you’ve got your vial full of steroid and ready to go. Before we go injecting, a quick hint that will allow you to inject more easily and possibly with a smaller needle. Heat up the syringe for a few minutes using either hot water or a hair dryer. This allows the oil to flow more freely and makes injecting much easier. You can also pre-heat your liquid your injecting with a water bath, heater, coffee pot base, etc-just warm it not boil it. The easiest spot to inject is in the buttocks. That’s the ass to all of you pottymouths. Unless your like me and your shaped like a Vagina and cant reach it easily..sorry but that's one of my drawbacks to using steroids for many years. To find the right spot, you’ll want to draw a vertical line down the center of your cheek and a horizontal line in the middle also to make four quadrants. It’s the upper outer quadrant that we want to inject into to avoid blood vessels and your sciatic nerve. Believe me, if you hit your sciatic, you’ll never make that mistake again! Conveniently, the right spot to inject is also the easiest to reach if you’re doing your own injections. If your life partner is helping you, (male or female) that’s fine as well just make sure your on good terms. Now, take an alcohol wipe and clean the areas you want to inject into. There are various injection techniques that you may want to learn at a later time, but we’ll stick with the most basic for now for convenience. Take the loaded syringe and hold it at a 90° angle to the skin. Now just stick it in at that angle. No need to go slow, as you only have a significant number of pain receptors in the skin and not many deeper. Once you’re in all the way, pull back on the plunger for a second or two. If you aspirate blood into the syringe, you’re probably in a vein and need to pull out and try again. If you don’t get anything (actually, you'll get some air bubbles), you’re good to go. Injecting too quickly is often a source of trauma to the area and unnecessary pain also known as PIP, so take your time. Some people will go as slowly as one cc per minute. I know you want to get the needle out of you as quickly as possible, but it’s worth in the long haul. Just don't move so much as you will scrape and cut the muscle with the needle. Once you’re done, just pull it out and hold some pressure with a piece of gauze for a few minutes to make sure the bleeding’s stopped. I use alcohol on a cotton ball and sometimes Put a Band-Aid on (preferably a Sesame Street character) and pull your pants up. Remember that forgetting to pull your pants up is bad form and will result in style points deductions from the public, no need to get all prison yard and show off your Sesame Street bandaid. Pull your damn pants all the way up!
If you’re doing frequent injections, you’ll want to rotate sites as much as possible to give each site a break. The thigh is another common site that people use and is easily accessed. To find the proper spot to use, you can stand at attention with your arms hanging at your sides and make note of where your middle finger reaches on your leg. This is about midway down your thigh on the outside part of it. Same techniques as before apply. The shoulder/delt is the final site that I will discuss. This is one pretty simple. Aim for the middle; it’s that simple. The issue of needle size and length is a personal one for the most part. Experience will tell you what you can and should use. For comfort’s sake, you’ll want to use the smallest needle you can pass the steroid through. Needle sizes are measured as the width across the opening of the needle and are represented as gauge (G). The lower the number, the bigger across the needle, and vice versa. So an 18G needle is very big AKA a HARPOON, while a 27G needle is very small like a SPLINTER. A typical size used for glute injections is a 1.5 inch 23G needle. Leaner guys can use a 1” needle and some people will prefer a higher gauge for comfort. Just don’t go any bigger than 22G as there’s no need, and you’ll end up taking cores of skin every time you inject. A 1” needle for thigh shots works well, and a 5/8” needle for delt injections seems to work for most. I use a 25g for this personally and it saves on my sesame Street band aides. If you’re fat, you should be dieting and not using steroids, but if you do, you will have to use a longer needle to reach the intramuscular space. This should be common sense, so diet first then consider your options unless you like needles and like them longer.
Well, we’ve only touched the tip of the iceberg here, and we still have lots more to cover. Tune in as I write Part II for a discussion about common steroids and how to use them best, about cycle planning and how to best avoid nasty side effects, and about anything and everything practical I can think of to give you. I realize that this is an article at the most basic level, but as I stated earlier, I want everybody to be on the same page before we delve into deeper issues.
Feedback is a plus, and we’ll go wherever you want with this in the future! You can post your replies here or feel free to Pm me if you want to keep your questions private. There is no such thing as a stupid question, if you ask a question its what makes the wise man wiser.

PG

I will write a column every month on a topic you guys want to know about-just send me your inquiries and suggestions.</o

Powderguy
02-17-2015, 03:19 PM
nobody likes to read huh?

akn
02-18-2015, 12:18 PM
bump good read for beginners covers almost all the basics

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bump good read for beginners covers almost all the basics

Powderguy
02-18-2015, 12:45 PM
I tried to add some humor as well, what do you think?

Presser
02-18-2015, 07:49 PM
honestly i thought it was a cut and past soon as i seen the spot injections dead link and didn't give it much thought thinking i probably read it before lol, as I've read just about everything out there over the years, i didn't know you actually wrote this until yesterday brutha!

Presser
02-18-2015, 08:27 PM
very good stuff brutha, took me a minute to read but i am going to add this to the front news page, and re title it a bit, if you want any specific title please let me know and i will edit it to what you want since you wrote it, but til i hear from ya I'm changing title to detail what article is plus i don't want an identical thread title here and on front page news.

Love original content!

Powderguy
02-19-2015, 09:03 AM
You can rename it as you wish. As long as its not a negative reflection of myself lol
Yes, I do write original articles with referenced material.
It is not a cut and paste and I referenced credit where its due. I appreciate the read and I hope others take a minute to read it as well.
My articles are always humorous, factual and informative.

Do what you need to with it brotha..as long as it helps others I'm all for it.

BEASTZ6
02-20-2015, 05:33 PM
Thanks Powderguy. Should be a must read for Noobs.