Impressive results with injectable desoxytestosterone
A new prohormone appeared a few months ago in the webshops: it goes by the name of*2-Delta*and contains 5alpha-androst-2-ene-17-one, a pretty inactive substance, which has to be converted in the body into 5alpha-androst-2-ene-17-ol. This on the other hand is a very interesting steroid, according to a 1964 study we came across recently.
We start with a little bit of chemistry, so we know what we're talking about. A few years ago webshops sold a designer steroid you may know as*DMT, desoxymethyltestosterone or*madol. It has a*notorious history*that you can read about in the Anabolics Book, the least well-known part of*the world's greatest website on performance enhancement. The structural formula of madol is shown in the left-hand diagram below.
17alpha-methyl-
5alpha-
androst-2-ene-
17beta-ol
(Madol)
5alpha-
androst-2-ene-
17beta-ol
(Desoxy-
testosterone)
5alpha-
androst-2-ene-
17-one
(2-Delta)
The diagram on the right above shows the structural formula of 2-Delta. It's really just ordinary DMT, but without the methyl group, and with a ketone group on C17.
The structural formula shown in the middle diagram is that of the steroid that this article is about. For simplicity's sake we call it desoxytestosterone. This substance, according to*Vida's anabolics bible, has half the androgenic effect of testosterone and at least 150 percent of the anabolic effects of testosterone. Vida's results, which were published in 1969, are backed up by animal studies from 1963*[J. Med. Chem., 1963, 6 (2), pp 156–161.]*and 1964*[Steroids Volume 3, Issue 2, February 1964, Pages 173-182.].
In 1964, chemists at the Czechoslovak Academy of Science in Prague noted an interesting property of desoxytestosterone. If you inject purenandrolone,*boldenone*or*testosterone, they have relatively little effect. Enzymes get rid of the vital 17beta-hydroxyl group, rendering the molecules inactive. That's why most oral steroids have a methyl group next to this site, and injectable steroids contain a fatty acid.
But desoxytestosterone works when it's injected. The researchers injected young rats once with 20 mg desoxytestosterone [2A], testosterone phenylpropionate [TPP],*nandrolone phenylpropionate*[19-nor-TPP] and ordinary testosterone [T]. The figures below show that desoxytestosterone increases the mass of the*Musculus Levator Ani*by about the same amount as do testosterone phenylpropionate and nandrolone phenylpropionate. On the other hand, the effect on the prostate was half that of testosterone phenylpropionate.
It therefore seems that the 17beta-hydroxyl group of desoxytestosterone is not sensitive to enzyme attacks, the Czechs reason. The stuff works fine, despite the fact that it doesn't have a fatty acid. At least it works fine when it's injected.
Now imagine that you manage to attach a fatty acid to the desoxytestosterone. What kind of steroid would you get then?
A new prohormone appeared a few months ago in the webshops: it goes by the name of*2-Delta*and contains 5alpha-androst-2-ene-17-one, a pretty inactive substance, which has to be converted in the body into 5alpha-androst-2-ene-17-ol. This on the other hand is a very interesting steroid, according to a 1964 study we came across recently.
We start with a little bit of chemistry, so we know what we're talking about. A few years ago webshops sold a designer steroid you may know as*DMT, desoxymethyltestosterone or*madol. It has a*notorious history*that you can read about in the Anabolics Book, the least well-known part of*the world's greatest website on performance enhancement. The structural formula of madol is shown in the left-hand diagram below.
17alpha-methyl-
5alpha-
androst-2-ene-
17beta-ol
(Madol)
5alpha-
androst-2-ene-
17beta-ol
(Desoxy-
testosterone)
5alpha-
androst-2-ene-
17-one
(2-Delta)
The diagram on the right above shows the structural formula of 2-Delta. It's really just ordinary DMT, but without the methyl group, and with a ketone group on C17.
The structural formula shown in the middle diagram is that of the steroid that this article is about. For simplicity's sake we call it desoxytestosterone. This substance, according to*Vida's anabolics bible, has half the androgenic effect of testosterone and at least 150 percent of the anabolic effects of testosterone. Vida's results, which were published in 1969, are backed up by animal studies from 1963*[J. Med. Chem., 1963, 6 (2), pp 156–161.]*and 1964*[Steroids Volume 3, Issue 2, February 1964, Pages 173-182.].
In 1964, chemists at the Czechoslovak Academy of Science in Prague noted an interesting property of desoxytestosterone. If you inject purenandrolone,*boldenone*or*testosterone, they have relatively little effect. Enzymes get rid of the vital 17beta-hydroxyl group, rendering the molecules inactive. That's why most oral steroids have a methyl group next to this site, and injectable steroids contain a fatty acid.
But desoxytestosterone works when it's injected. The researchers injected young rats once with 20 mg desoxytestosterone [2A], testosterone phenylpropionate [TPP],*nandrolone phenylpropionate*[19-nor-TPP] and ordinary testosterone [T]. The figures below show that desoxytestosterone increases the mass of the*Musculus Levator Ani*by about the same amount as do testosterone phenylpropionate and nandrolone phenylpropionate. On the other hand, the effect on the prostate was half that of testosterone phenylpropionate.
It therefore seems that the 17beta-hydroxyl group of desoxytestosterone is not sensitive to enzyme attacks, the Czechs reason. The stuff works fine, despite the fact that it doesn't have a fatty acid. At least it works fine when it's injected.
Now imagine that you manage to attach a fatty acid to the desoxytestosterone. What kind of steroid would you get then?
