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Jo_seef
07-16-2015, 07:23 PM
How safe is trenbolone?

Thousands of bodybuilders inject themselves with trenbolone despite the fact that we know so little about the side effects of this anabolic steroid. That's why Australian researchers tested trenbolone on rats, in the hope that it has the desirable features of testosterone but not the undesirable ones. If this turns out to be the case, then trenbolone might be useful for men who produce too little testosterone.

Trenbolone
Many of the undesirable characteristics of testosterone are the work of estradiol and DHT, both products of testosterone conversion. Because trenbolone cannot convert into those metabolites, American researchers have suggested that trenbolone might be a SARM.*[Steroids. 2010 Jun;75(6):377-89.]

According to*Androgens and Anabolic Agents: Chemistry and Pharmacology*by Julius Vida, trenbolone is a kind of super-nandrolone. Which means that studies where rats have been injected with trenbolone have shown that the relationship between trenbolone's androgen and anabolic qualities is similar to that of nandrolone. But both the androgenic and anabolic effect of trenbolone are considerably stronger than those of nandrolone.

The figure below comes from*Androgens and Anabolic Agents.



In 2002 American researchers compared the anabolic and androgenic effects of trenbolone with those of testosterone propionate. This study showed that trenbolone has noticeably fewer androgenic effects than testosterone propionate does.*[Toxicol Sci. 2002 Dec;70(2):202-11.]

Study
The Australian researchers implanted a pump in their rats, which released 2 mg trenbolone per kg bodyweight daily for six weeks. [TREN] Rats in a control group were given a pump with no active ingredients. [CTRL] Thehuman equivalent*of the dose studied is about 20-30 mg trenbolone per day.

*

Results
At the end of the six weeks, the trenbolone rats were lighter than the animals in the control group. They had gained lean body mass and lost a fair amount of fat mass.

*



The trenbolone rats' prostate however had become 49 percent larger than that of the rats in the control group. That sounds serious so the researchers examined the organ in minute detail. They found no inflammation or cancer cells.

This is probably because trenbolone reduced the estradiol level. Trenbolone also had the same effect on the rats' testosterone level. Trenbolone had almost no effect on dimensions or structure of the testes, unlike the effects seen when testosterone is administered to rats in studies.

Trenbolone increased the rats' insulin sensitivity - and therefore reduced the HOMA-IR. This is probably a result of the effect on body composition.


The level of triglycerides and LDL in the rats' blood went down, which is a desirable effect. The HDL level decreased too, however, which is an undesirable effect.

The researchers detected no effects on liver enzymes. So in the dose tested, trenbolone is not dangerous for the liver.

Conclusion
"Further investigation into the comparative benefits conferred by trenbolone therapy relative to the current gold standard, testosterone, are well justified by these findings", the researchers conclude. "Particularly in relevant models of obesity and metabolic dysregulation."

Source:*
Steroids. 2015 Feb;94:60-9.
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DefMetalLifter
07-17-2015, 02:47 PM
Idk but I love it! Ran three cycles of it in the last year! Many more to come! Tren turns you from human to beast! I even have hair growing in places I never did!


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Mountain_Man
07-17-2015, 02:52 PM
Idk but I love it! Ran three cycles of it in the last year! Many more to come! Tren turns you from human to beast! I even have hair growing in places I never did!


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same here been using tren for over 16 years i could not cycle without it

yellow snow
07-17-2015, 05:15 PM
If you can handle the sides, it is the necture of the gods!!!

Mountain_Man
07-17-2015, 05:32 PM
If you can handle the sides, it is the necture of the gods!!!
true i dont get sides from tren -e and that is all i run now

Mrbigz
07-17-2015, 05:33 PM
Prami, and masterone control all sides of tren. Making it the absolute nessecit to be big and shreaded.

Mountain_Man
07-17-2015, 05:41 PM
Prami, and masterone control all sides of tren. Making it the absolute nessecit to be big and shreaded.
cool maby that is why i dont get any sides i always run it with masterone e thanks for that info brother

charliebigspuds
07-17-2015, 06:11 PM
I hate tren. Sides kill me. Would love to run it. Just can't. Maybe @ 50mg but still insomnia is a bitch for me.

yellow snow
07-17-2015, 08:25 PM
Prami, and masterone control all sides of tren. Making it the absolute nessecit to be big and shreaded.
I have never tried it with mast. I am trying it with prami for the first time and honestly now that I think about it the only side I have is night sweats.

The anger and insomnia are almost non existant.

Next year I am going to do a cut with mast, prami, test, tren, winnie...............should be killer.

Presser
07-18-2015, 08:16 AM
I hate tren. Sides kill me. Would love to run it. Just can't. Maybe @ 50mg but still insomnia is a bitch for me.

for those with super sensitivity to tren ace i honestly think even 25mg daily is enough to feel it and see it working really well combined with your normal testosterone dosage

Mrbigz
07-18-2015, 10:46 PM
Yes I agree tren never down regulates it always will continue to build muscle. Masterone helps with insomnia guys, trust me on this. keep your tren and masterone dose almost the same. You'll feel great. Also benefit as well with masterone is if your running test it will control any estrogen side effects.
prami run it .5 mg a.m. and .5 pm. Will eliminate all tren sides and give you extra boost in sex drive guys. And won't make you sick Either prami for me makes me sick as hell if I take 1mg or more at a time. Splitting it up is alot better.