d12hazz

MuscleChemistry Registered Member
There’s an incredible new steroid substitute on the market known as SARMS (Selective Androgen Receptor Modulators). SARMS is said to be the most effective for steroid cycles and PCT (post cycle therapy). But what do we know about it? Today, I’ll talk about SARMS and with luck, help you understand everything there is to know about it.
[h=2]What are SARMS?[/h]
SARMS Chemical Composition
SARMS – “Selective Androgen Receptor Modulators”. Androgens are a unique type of hormones that act as ligands (a molecule connected to another molecule) that attach to cellular androgen receptors. The androgen receptor is included in a compound signal transduction pathway that eventually leads to superior expression of specific genes.
All anabolic steroids and prohormones give their muscle building properties through this attachment to the androgen receptor.

Selective receptor modulator is a drug that can either obstruct or fuel similar nuclear hormone receptor in various circumstances. If it can hamper or fuel a receptor in a tissue selective manner, it can be capable of imitating the valuable effects in one tissue and simultaneously decrease the undesirable effects of the natural or artificial steroidal hormones in other tissues.
[h=2]SARMS vs. Prohormones[/h]Prohormones hit the scene first. But the problem with anabolic steroids or testosterone supplements is that they are poor in mimicking the muscle building effects of genuine steroids and they mostly have the same negative side effects which is why it was an impossible winning combination.
SARMS on the other hand, are not an imitation of steroids – they’re an upgrade. It can be given orally (whereas presently used androgens come in injectable forms which result to unwanted instabilities in testosterone blood levels). They’re said to treat various illnesses that were formerly treated with anabolic steroids and other medicines. SARMS has the potential to take the place of androgen which can produce the same positive results on muscle tissue as anabolic steroids.
[h=2]How Do SARMS Work?[/h]Strength, power and skeletal muscle mass decline when men and women get old due to the loss of type 2 muscle fibers. This impedes individuals to function normally. SARMS can increase skeletal muscle mass and boost strength in androgen-deficient individuals. Though they are similar to anabolic steroids, SARMS are more selective in causing muscle growth.
SARMs can be given either in injectable dosage or oral form. The anabolic effect has been estimated to be similar as testosterone. Also, it’s been shown to yield dose-dependent increases in bone mineral density and mechanical strength aside from being able to minimize body fat and maximize lean body mass.
[h=2]The Benefits[/h]SARMS is said to have the potential to harness the benefits of anabolic supplementation while decreasing the side effects of steroids. These benefits include:

  • Non-toxic, oral form without causing liver damage
  • Similar effects with testosterone
  • Does not obstruct your HPTA to the large extent of steroids
  • No alteration to estrogen and Dihydrotestosterone (a hydrogen hormone)
  • Undetectable
  • LEGAL
For bodybuilders, taking SARMS will give:

  • Prevention of muscle loss (when cutting)
  • Lean muscle development
  • Injury restoration
  • PCT use after anabolics
  • Enhanced strength
  • Endurance
  • Joint healing abilities
[h=2]Side Effects of SARMS[/h]The great thing about SARMS is that its side effects are small making it not an issue unless taken in high doses for a long time. When used for 4 weeks or more, the following side effects can occur:

  • Gynecomastia (growing of male breasts)
  • Virilization in women (development of male characteristics such as deepening of the voice and Adam’s apple and it may cause infertility)
  • Acne
  • Testicular atrophy (a decrease in size of male reproductive organs)
  • Baldness
*Regulating intake of SARMS will go a long way in assisting you achieve the benefits of SARMS while evading the side effects at the same time.
[h=2]The Most Popular SARMS[/h]There are many possible SARMS but these are the 4 main SARMS that are presently available and most applicable to bodybuilders, athletes and fitness buffs:

  • Ostarine (MK-2886) – selective for anabolic activity at certain androgen receptors, effective in sustaining and enhancing lean body mass and recomping (losing body fat and adding it as muscle while staying the same weight)
  • S4 (Andarine) – selective for bone tissue (mainly low virilization), intended for osteoporosis and doesn’t create the development of prostate and other secondary sexual organs
  • GW 501516 (Cardarine) – melts fat without muscle loss and gives you the push you need to train better and stronger than ever
  • LGD-4033 – a powerful, non-steroidal bodybuilding supplement for increasing lean muscle mass and decreasing body fat


Note: GW-501516 is often mistaken as SARMS but it is a PPAR receptor agonist, not selective androgen receptor modulators.
To close this post, SARMS is still in its early phase of development. But obviously, there are plenty of pharmaceutical companies developing different SARMS compound making its potential high and bright.
 
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