Iron Game

Veteran
Growth Hormone and IGF-I: Two Might Be Better than One for Muscle Growth

Growth hormone (GH) and insulin-like growth factor (IGF-I) are powerful anabolic hormones that promote muscle growth and fat use. During the 1980s, as part of the space program, Dr. John Linderman from the University of Toledo in Ohio showed that the combination of GH and IGF-I promoted muscle hypertrophy better than either hormone alone.
Michael Graham and co-workers from Newman University in Great Britain, in a review of literature, speculated that the combination of hormones would be effective for preventing muscle loss with aging (sarcopenia). Sarcopenia is a devastating aspect of aging. Reduced muscle mass in the lower body and low levels of muscle strength are linked to premature death and an increased risk of diabetes. We need well-controlled scientific studies to determine the effectiveness of supplementing both hormones on muscle hypertrophy and preventing muscle wasting during aging. (Journal of Exercise Physiology, online December 2009)
 
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