ANABOLISM VS. ANDROGENISM
a·nab·o·lism ( P ) Pronunciation Key (-nb-lzm)
n.
The phase of metabolism in which simple substances are synthesized into the complex materials of living tissue.
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[ana- + (meta)bolism.]
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anabolic
\An`a*bol"ic\, a. [Gr. ? something heaped up; ? + ? a stroke.] (Physiol.) Pertaining to anabolism; an anabolic changes, or processes, more or less constructive in their nature.
an·dro·gen
n.
A steroid hormone, such as testosterone or androsterone, that controls the development and maintenance of masculine characteristics. Also called androgenic hormone.
andro·genic adj.
androgenic
adj : of or related to the male hormone androgen
Along with the androgenic changes comes the ‘anabolic’ effect. Anabolism is defined as any state in which nitrogen is deferentially retained in lean body mass through the stimulation of protein synthesis and/or a reduction in protein breakdown.It includes growth promotion, protein and collagen synthesis and an increase in muscle size and bone metabolism.Characteristically, steroids that are more anabolic present weaker AR bindings, and those that are more androgenic strongly bind the AR, exerting a more potent effect. A‘myotrophic-androgenic index’, based on the association between anabolic and androgenic bio assays in rats has been previously described. Although these assays were subject to several criticisms because of their unsophisticated in vivo nature, the activity of many substances was assessed, allowing comparison between different substances.Since testosterone is the basic AAS, it has a1:1 anabolic-androgenic ratio.
All steroids are derivatives of synthetic testosterone, all steroids possess both androgenic and anabolic properties, and all steroids bind to the same receptor. Some steroids have been bio-chemically engineered, however, to exhibit more anabolic properties and fewer undesireable androgenic side effects. Deca-Durabolin - nandrolone decanoate - , primo, equipoise, masteron are examples of such drugs........and Deca-Durabolin - nandrolone decanoate - is the original.
The standard scientific measurement of the androgenic/anabolic ratio of a given steroid is a comparison of the effects of the drug on the growth of prostate tissue vs. skeletal muscle tissue.
For example, in such tests, esterless Deca-Durabolin - nandrolone decanoate - exhibits 80% less effect on the growth of prostate tissue (bad stuff) and 240% more effect on growth of skeletal muscle tissue (good stuff) than does esterless testosterone.
a·nab·o·lism ( P ) Pronunciation Key (-nb-lzm)
n.
The phase of metabolism in which simple substances are synthesized into the complex materials of living tissue.
-------------------------------------------------------------------------------
[ana- + (meta)bolism.]
--------------------------------------------------------------------------------
anabolic
\An`a*bol"ic\, a. [Gr. ? something heaped up; ? + ? a stroke.] (Physiol.) Pertaining to anabolism; an anabolic changes, or processes, more or less constructive in their nature.
an·dro·gen
n.
A steroid hormone, such as testosterone or androsterone, that controls the development and maintenance of masculine characteristics. Also called androgenic hormone.
andro·genic adj.
androgenic
adj : of or related to the male hormone androgen
Along with the androgenic changes comes the ‘anabolic’ effect. Anabolism is defined as any state in which nitrogen is deferentially retained in lean body mass through the stimulation of protein synthesis and/or a reduction in protein breakdown.It includes growth promotion, protein and collagen synthesis and an increase in muscle size and bone metabolism.Characteristically, steroids that are more anabolic present weaker AR bindings, and those that are more androgenic strongly bind the AR, exerting a more potent effect. A‘myotrophic-androgenic index’, based on the association between anabolic and androgenic bio assays in rats has been previously described. Although these assays were subject to several criticisms because of their unsophisticated in vivo nature, the activity of many substances was assessed, allowing comparison between different substances.Since testosterone is the basic AAS, it has a1:1 anabolic-androgenic ratio.
All steroids are derivatives of synthetic testosterone, all steroids possess both androgenic and anabolic properties, and all steroids bind to the same receptor. Some steroids have been bio-chemically engineered, however, to exhibit more anabolic properties and fewer undesireable androgenic side effects. Deca-Durabolin - nandrolone decanoate - , primo, equipoise, masteron are examples of such drugs........and Deca-Durabolin - nandrolone decanoate - is the original.
The standard scientific measurement of the androgenic/anabolic ratio of a given steroid is a comparison of the effects of the drug on the growth of prostate tissue vs. skeletal muscle tissue.
For example, in such tests, esterless Deca-Durabolin - nandrolone decanoate - exhibits 80% less effect on the growth of prostate tissue (bad stuff) and 240% more effect on growth of skeletal muscle tissue (good stuff) than does esterless testosterone.
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