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Presser
08-07-2016, 11:24 AM
Understanding how steroid hormones convert into estrogen

Which steroids convert or Aromatize into estrogen or progesterone.

How to Stop the Bloat from excessive estrogen

Which drugs cause gyno (bitch tits).

<big>Aromatization</big> is the process by which the body converts anabolic steroids and/or testosterone into <big>estrogen</big>. We all know this but what isn't so obvious is the reason why and why, it is so important to understand. The human body loves balance. The term homeostasis represents the body's love of static systems within the body. It likes to keep everything: muscle mass, fat levels, hormones, neurotransmitters, overall bodyweight, in a narrow range. There are many systems of checks and balances in the body. If one fails, there is usually another one which can pick up the slack.



In the case of aromatization, the body converts some of the exogenous (injected or swallowed, hormone from an outside source) into estrogen to try and keep a balance between male and female hormone in the body. Even male bodies have natural amounts of the female hormones estrogen and progesterone. What they don't have natural amounts of is hundreds and in some cases thousands of milligrams of testosterone floating around. The average male who does not have horse nuts produces about 7mg per day. That is Just under (49) fifty milligrams per week. The weakest injectable testosterone you can find is fifty, and nobody uses it because it's too weak. So what do you think happens when we dump five hundred milligrams of test into our bodies...yup, estrogen goes up. It has to, the body likes balance and narrow ranges, remember?



What to do about this excess estrogen? Well, the thing of it is, if estrogen goes up yet stays in proportion to the increased testosterone, we don't have to worry too much. If for some reason, your genetics like to produce an enzyme called aromatase, you might be screwed if you haven't already read what I am about to tell you. Aromatase is an enzyme that has converting test into estrogen as its primary function. The more aromatase you have in your body, the more test to estrogen conversion you will have as well. How do you know if you genetically have high aromatase levels? You don't. You can't. Not until its a little late anyway. If you are a seasoned juicer which most of you reading this probably are, you already know if you tend to get sore in and around the nipple when on a cycle of roids. If you are like some of my buddies though, and only take the drugs I call "pretty boy drugs" such as winstol, deca, primo, anavar, etc...you may not yet know if you are susceptible. The reason these drugs are known as fat-loss anabolics is simply due to the fact that they have little to no aromatizing qualities, even in the presence of large amounts of aromatase. One of my buddies was fine with the five or six cycles of winnie combos he had done...until he decided to take some dianabol for some stronger gains. He developed instant soreness in both nips-damn that sucks! Good thing he knew someone who knew what they were doing to bail his ass out!!



The drugs most commonly affiliated with gynocomastia (bitch tits) are in no specific order: dianabol (both liquid and pill), anadrol, all testosterone esters (yes, even prop), test suspension, and sometimes even deca! Damn man!! That pretty much names all the heavy hitters. Read on my friends, there are plenty of ways to get around most if not all cases of susceptibility to gyno (if only the Rock new this, he may not have ever had to wear those ridiculous band-aids on his nips).



Okay, so the most important thing concerning water retention is aromatization of testosterone into estrogen. The ratio of testosterone to estrogen is what determines how severe your chances are for developing serious estrogenic affects such as gyno. So what do you do if you are one of the unlucky few who are susceptible to gyno? What if you just want to use strong drugs but don't want the water? What if you are prone to "potato" head syndrome and seem to bloat up no matter what? Your answer lies in proper use and understanding of anti-estrogen and anti-aromatase drugs.
http://www.anabolicsteroids-hormoneknowledge-bigmuscles-drugs.com/images/estrogenstructure.gif (https://sellfy.com/p/teuN) http://www.anabolicsteroids-hormoneknowledge-bigmuscles-drugs.com/images/4ringstructure.gif
Above is the chemical structure of estrogen. Notice how the "A" ring is fully aromatic or "all filled in". This filled in structure is called an aromatic ring and is a key functional group in all estrogens. Keep this "A" ring in mind as it will help us to understand how different anabolic steroids are aromatized into estrogen. Take a look here at the testosterone molecule and notice how similar these two structures are.
http://www.musclechemistry.com/upload/image/webp;base64,UklGRsACAABXRUJQVlA4TLQCAAAv08AkACegkJ EkNncN5IvTA7xiRpLg4Fwg8xufRVg1bRvBwX5TyRTMAbn5jyT/p3p2dfcgO5IkS1LyIyXgUOAeEpwhQMKm/kpdd1d1VzVvsIj O3Akt22WPjHupNwg5gf E2uELOsKZP6gAL7jzeKe6w TuRBqiRO5sOdJBsJ7ruvx5 btPQBN4Qfvn5ehdG3m3V4uYLYnz9Z2fk7nsZwB1JqnT5cQGQHf g64BcFt0L33nzQy BtxEr3lu0kvCBs3WUDZ2UDOtpkTftfIKjpSgk58TopKwD uTKEcfRSfMQPSZomuCGMhtYOrlEN/97CkbS bnWcX7bsS uExYHbbBr S7gBpYH4I9NUxy Nkon914YVNxSHRbS9yf5WgjokRC5bNnqXZnKXbfL4pnD1PrvmP Uzp6m1H3PODxLmGYZh52sUngYXwVQx9HZuXl5DFE0b4bFb4 v/Zl3e/tWQ82D/KWmOe6hD7kIlfB8D7ZLoO9BPyKOf4BL0Xn8HYS B3WlaowDKg26jdtgU0lgb4xF7YKxKOaIE2DeLysfH18zDDBRBc h10qo/dJDFcRFDxQEsLFXJ3J8PThJB2dkpuo7najuJN94CrZMIYo2TOV Ovinpl7DLm7j/E4UVG7BM/iVokgI0Iqe0MDoVFTRlgI8aaomj6y0Z57 taomyvwJSpjTDRRzYoaiPQVvLWv4xUUTFeJRGxRv8vh k80BAprX7QVDoFcGfcVoJMKpkC8pkUjuFlKqcol3INS zE5V4VCxr9R0w7UwBYHydZB6kxzZ2FtGw00fJZXaSUOGF0kVgk LgOmlikkymTLIIqQrTj2VDWFKtfgo0QWiqdqRd5jurK3/ogpE Nktl4SmPcrstjbWy8 VCrl7a2XOYgy5by9 TmuNPoe0x3bErrG6561v1AQ8k cAQ==http://www.anabolicsteroids-hormoneknowledge-bigmuscles-drugs.com/images/4ringnumberedstructure.gif (https://sellfy.com/p/teuN)
The aromatase enzyme cleaves the CH3 (methyl) group from the 19th position on the diagram. This causes the need for a hydrogen to link with the oxygen at the #3 position (this is just the way steroid biochemistry works). The reasons for this specific event are not so important to us, we just need to know that aromatase cleaves off the methyl group at C19 and this causes the transition from the hormone into estrogen.


You could say aromatase "attacks the 19th carbon, removes it, and estrogen is the result". This is why molecular biochemists refer to estrogen as a member of the "18 Carbon Series". Estrogenic hormes have only 18 carbons, androgens on the other hand, have 19.


In other anabolic steroid structures, the "A" ring may have a specific configuration such that the 19th carbon is protected from aromatase. If this is the case, the steroid cannot be aromatized. A good example of this is the chemical structure of winstrol or trenbolone. Take a look...
http://www.anabolicsteroids-hormoneknowledge-bigmuscles-drugs.com/images/winstrol.gif http://www.anabolicsteroids-hormoneknowledge-bigmuscles-drugs.com/images/trenbolone.gif http://www.anabolicsteroids-hormoneknowledge-bigmuscles-drugs.com/images/4ringnumberedstructure.gif
The extra ring preceding the "A" ring of winstrol molecule chemically "stabilizes" it and protects the "A" ring from losing its 19th carbon. Basically, the 19th carbon becomes stubborn with the extra ring attachment that winstrol demonstrates. This stubborness does not allow the 19th carbon to be removed, and thus, winstrol is NON-aromatizable.


The trenbolone has a double bond between carbon 9-10. This also stabilizes the structure and the absence of a methyl (CH3) from carbon #10 makes tren NON-aromatizable as well.


So, chemically speaking, estrogen has an "aromatic A ring" (all filled in with those three lines inside it) and a methyl group (CH3 thingy) from the steroid removed from the #10 carbon position. These two main characteristics make a four ring steroidal structure into a functional estrogen.

http://www.anabolicsteroids-hormoneknowledge-bigmuscles-drugs.com/aromatization.html

jimbosmith316
08-07-2016, 11:29 AM
Great post! Balance is the key

beachbody
08-07-2016, 11:30 AM
It looks like AI's can solve most of this problem.