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    Ostarine - SARMs Profile

    Ostarine: SARM-4, S-4)

    Family: Selective Androgen Receptor Modulator

    Half Life: About 4 hours

    Formula: C19 H18 F3 N3 O6

    Chemical Structure: S-3-(4-acetylamino-phenoxy)-2-hydroxy-2-methyl-N-(4-nitro-3-trifluoromethyl-phenyl)-propionamide

    Anabolic Rating: Similar to Testosterone Propionate

    Facts: Ostarine (*S-4) is a Selective Androgen Receptor Modulator produced by GTx Inc, which is currently in the investigational stages of development. A SARM is exactly what it sounds like: a compound (not an anabolic steroid) which has the ability to stimulate the androgen receptor (much the same way as anabolic steroids). Unfortunately, due to its status as a drug still in the developmental stage, most of the research on it has been done in rodents and trials only.

    S-4 is an orally active (and highly bioavailable) selective agonist for androgen receptors which was shown to have anabolic effects in muscle and bone tissue. It has been shown to have no measurable effect on lutenizing hormone (LH) or follicle-stimulating hormone (FSH), but it has been shown to have some effect on prostate weight, with an androgenic potency around 1/3rd of its anabolic potency. Still, this is a good trade-off, because it’s anabolic effect has been measured to be roughly the same as testosterone. It has also been shown to produce dose-dependent increases in bone mineral density and mechanical strength in addition to being able decrease body fat and increase lean body mass .

    Unfortunately, it has a short half-life in humans of only 4 hours, and thus far has only gone through phase II clinical testing in humans .

    Practical Use: This compound has potential use for all aspects of male hormone replacement therapy, and could eventually replace testosterone for this purpose. Since there is currently no accepted test for SARMs, athletes who are subject to drug testing would find it to be a suitable replacement for anabolic steroid use. Since it doesn’t effect LH or FSH, it may also be a highly useful anabolic agent to be used while attempting post-cycle therapy.

    Side Effects: Prostate enlargement (1/3rd of what is seen with testosterone) and potential acne are potential side effects, although most users don’t report either of them; much more common are vision problems (floaters, yellow-tinged vision). Water retention, gynecomastia, and most other steroid-related side effects are probably not possible. In addition, inhibition of natural hormone levels is probably minimal or nonexistent at worst.

    Used By: user's have successfully used S-4 and can attest to its potency and lack of side effects – but since it has only recently appeared on the black market (in very limited quantities), very few people have gotten the opportunity to try it. I suspect that some high-level athletes have gotten their hands on it, as have a small handful of bodybuilders. In the coming years we can expect it to become an accepted part of the underground pharmacopeia.

    Typical Dose: user's have tried several different dosing protocols with this drug, ranging from only pre-workout, to only post-workout, to every day and every other day. For them, 100 milligrams prior to workouts and 100 milligrams in the morning (on non-workout days) appears to work best.

    Stacks Well With: S-4 can be used in place of testosterone in virtually any cycle. In a very practical sense, because it causes no water retention, I suspect that it will be used very successfully in the final stages of pre-contest cycles for bodybuilders (or as a very potent stand-alone for athletes under doping controls).
    Last edited by Presser; 12-14-2012 at 11:07 AM.
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    Ostarine might also be known as
    ((2S)-3-(4-cyanophenoxy)-N-[4-cyano-3-(trifluoromethyl)phenyl]-2-hydroxy-2-methylpropanamide) , MK-2866 , Enobosarm


    So what exactally is Ostarine? Well Ostarine is a SARM, which stands for selective androgen receptor modulator, and was developed at first to treat conditions such as muscle wasting and osteoporosis. This is a great compound as it can be used safe and effectively. It is not a Anabolic Steroid, so there will be no need to worry about all of those horrible side effects! You can expect a great increase in overall lean muscle mass, strength, and bone density. Ostarine can stimulate the androgen recepor, similar to the way steroids do. Which has anabolic effects in muscle and bone tissue. It does not have an effect on the lutenizing hormone or follicle-stimulating hormone. However it has been show to cause prostate weight. We use a pharmaceutical grade powder which contains only 100% Ostarine in every capsule and nothing else! No added proprietary blends!


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