1. #1
    Stage Pro Board Certified MD
    gandhisays's Avatar
    Join Date
    Dec 2008
    Posts
    8,927
    Rep Power
    2147492590

    Default Equipoise. Boldenone is a derivative of testosterone. Muscle Growth Effects



    Anabolic Pharmacology

    By Seth Roberts
    Equipoise
    Pharmacology is the study of drugs and their effects. Anabolic pharmacology is the study of drugs that have a growth-promoting effect in muscle. This column will explore anabolic pharmacology by profiling a different anabolic drug and its effects each month. The focus of discussion this month will be the anabolic androgenic steroid, Equipoise.
    Boldenone is a 1-dehydro derivative of testosterone that has been sold as a veterinary preparation under the name Equipoise, and is largely known by this name. The formation of a double-bond in the 1,2 position changes the shape of the molecule slightly. This also changes the potency and characteristics of the molecule. Boldenone has a lower affinity than testosterone for the androgen receptor, making it less potent on a milligram-for-milligram basis.1 This steroid can be converted to estrogen, but less so than testosterone. In addition, boldenone is metabolized to 1,4 dienedione, which is a potent aromatase inhibitor.
    Boldenone is converted by 5-alpha reductase to 1-testosterone, a more potent steroid, as well as to the 5-beta isomer— which is thought to be an inactive metabolite.2,3 Binding to sex hormone-binding globulin (SHBG) is much lower with boldenone than with testosterone, meaning a larger free plasma concentration but a shorter half-life in plasma.4 There is little-to-no binding to progesterone or glucocorticoid receptors, and no real data on the interaction of boldenone with the different enzyme systems.1
    The undecyclenate ester of boldenone was the ester marketed under the original trade name. In recent years, the free base and other esters have become available as underground preparations. On the street, Equipoise is erroneously considered to have the same activity as Deca and is often substituted for Deca in a stack. Dan Duchaine, if not the originator of this myth, at the very least propagated it in his book Underground Steroid Handbook II. If you look at the structure, you can see that boldenone is structurally identical to dianabol without the C-17 alkylation.
    Most people experience much less side effects with boldenone, compared to methandrostenolone. This is because boldenone converts to estradiol, while methandrostenolone converts to methylestradiol. Methylestradiol is a much more potent and long-lasting estrogen than plain estradiol. Since there is no C-17 alkylation, there is no liver toxicity associated with boldenone. Boldenone is rumored to be very good at increasing red blood cell production. While all androgens stimulate erythropoiesis, there is no evidence in the scientific literature that boldenone is superior in producing this effect.5,6,7,8
    Boldenone undecyclenate is generally injected every four or five days, but some people will inject every day while others will inject once per week. The longer half-life of the undecyclenate ester would dictate an injection frequency of every 10-14 days, but there has been a trend toward more frequent dosing by anabolic-androgenic steroid (AAS) users, even with drugs known to have long half-lives. Dosing is generally kept pretty low (300-500 milligrams per week), but the low binding affinity would argue for twice that dosage, taken with testosterone.
    The anabolic-to-androgenic ratios are favorable for boldenone, but people do not consider boldenone a particularly potent steroid— possibly due to the low doses that are utilized. Also, boldenone does not cause much water retention— so many people assume it is not working if they do not put on 10 pounds in one week. Boldenone is said to cause an increase in vascularity, although there is no mechanism to explain why boldenone would do this more than any other AAS.
     

  2. #2
    MuscleChemistry Newbie Board Certified D.V.M.

    Join Date
    Mar 2015
    Posts
    29
    Rep Power
    0

    Default

    So is equipoise and boldenone the same thing? Nice article btw
     

  3. #3
    MuscleChemistry Registered Member Board Certified DMD
    Powderguy's Avatar
    Join Date
    Oct 2014
    Posts
    983
    Rep Power
    2147484640

    Default

    Equipoise is the trade name and boldenone is the chemical name. Its boldenone undecylenate, which is the full chemical name. Good question, dont be afraid to ask if your not sure. just remember Boldenone can be any chemical in the series, base, long ester or short ester.
    Thanks IronJulius thanked for this post
     

  4. #4
    MuscleChemistry Senior Board Certified Psy.D

    Join Date
    Mar 2015
    Posts
    487
    Rep Power
    2147484144

    Default

    Great info, I am about to start a cycle with eq in the mix.
     

  5. #5
    Presser's Avatar
    Join Date
    May 2002
    Posts
    41,682
    Rep Power
    2147525351

    Default

    i haven't run eq in ages,
    Equipoise. Boldenone is a derivative of testosterone. Muscle Growth Effects

  6. #6
    MuscleChemistry Guru Board Certified CPH
    BEASTZ6's Avatar
    Join Date
    Jan 2009
    Posts
    1,750
    Rep Power
    2147485413

    Default

    One of my favs to run with test.
     

  7. #7
    MuscleChemistry Senior Board Certified Psy.D

    Join Date
    Jun 2014
    Location
    Lisbon, Portugal
    Posts
    470
    Rep Power
    720

    Default

    Quote Originally Posted by BEASTZ6 View Post
    One of my favs to run with test.
    Which Test base do you run it with? I'm currently running it with Prop for 16 weeks.
     

  8. #8
    MuscleChemistry Guru Board Certified CPH
    BEASTZ6's Avatar
    Join Date
    Jan 2009
    Posts
    1,750
    Rep Power
    2147485413

    Default

    [QUOTE=KletoReese;709044]Which Test base do you run it with? I'm currently running it with Prop for 16 weeks.[/QUOTE

    Running EQ with test cyp right now. I have some test prop that I will be switching to at 100 mg/EOD and kicking the EQ up to 600 mg/wk.
    Likes drtbear67 liked this post
     

  9. #9
    Musclechemistry Board Certified Member Board Certified MD
    drtbear1967's Avatar
    Join Date
    Aug 2016
    Location
    Kentucky
    Posts
    5,663
    Rep Power
    2147489318

    Default

    bump
    Get It Done!

Similar Threads

  1. IGF-1 and Muscle Growth - A powerful mediator of Muscle Growth
    By Chris250 in forum MuscleChemistry Discussion
    Replies: 12
    Last Post: 02-01-2016, 04:16 AM
  2. Boldenone, Equipoise,Boldenone Undecyclenate Ganabol, Equigan and Ultragan
    By gandhisays in forum Bodybuilding Steroid & Training Articles
    Replies: 1
    Last Post: 05-13-2014, 06:07 AM
  3. Steroids, Myth or Miracle. Testosterone Equipoise, Deca, Anadrol, dianabol, Effects
    By gandhisays in forum Bodybuilding Steroid & Training Articles
    Replies: 2
    Last Post: 03-27-2014, 09:05 AM
  4. Boldenone Undeclynate (equipoise) while dieting
    By bsm1985 in forum MuscleChemistry Discussion
    Replies: 8
    Last Post: 12-23-2012, 11:50 PM
  5. THE EFFECTS OF TESTOSTERONE. The effects of test cypionate.
    By big in vegas in forum Bodybuilding Steroid & Training Articles
    Replies: 1
    Last Post: 10-11-2012, 07:53 PM

Posting Permissions

  • You may not post new threads
  • You may not post replies
  • You may not post attachments
  • You may not edit your posts
  •  

Log in

Log in