1. #1
    Stage Pro Board Certified MD
    gandhisays's Avatar
    Join Date
    Dec 2008
    Posts
    8,927
    Rep Power
    2147492590

    Default DNP and Fat Loss. DNP Cycle Dosages.

    THE SKINNY ON DNP

    IUPAC name: 2,4-Dinitrophenol
    Molecular formula: C6H4N2O5.
    Molar Mass: 184.106
    Density: 1.683 g/cm³
    Melting Point:108 °C, 381 K, 226 °F
    Boiling Point: 113 °C, 386 K, 235 °F
    Acidity: 4.114


    What is DNP?

    For purposes of this article we will stick to the physiological application of DNP. If I had to describe DNP in one word…poison. DNP prevents normal chemical reactions at the cellular level. It impedes the normal function of cellular metabolism.

    Where did DNP Come from?

    The US Army categorizes DNP as a potential insensitive munitions compound because it was used to ignite TNT in the early 1900’s. DNP was found to have other properties that made it useful for making dyes, wood preservatives, photographic developer, and pesticides. DNP is highly toxic, and people working with or around the substance can develop side effects like weight loss, high fever, and death. The weight loss aspect prompted studies regarding the effects of DNP on metabolism.

    How does DNP work?

    DNP makes changes in our metabolism. Metabolism is the set of chemical reactions in our bodies that keep us alive. Our bodies metabolize nutrients to provide us with energy. Oxidation involves the transfer of electrons between atoms (or molecules) and releases energy. The formal name for this process is oxidative phosphorylation. When our body breaks down nutrients and absorbs then into our cells, one of the functions of the cell’s mitochondria is to produce chemical energy called ATP. In order to create ATP, mitochondria capture and use the energy released from oxidative phosphorylation.

    DNP is known as a mitochondrial uncoupler of oxidative phosphorylation. In other words, DNP encapsulates and moves protons (ions) across cell membranes, preventing mitochondria from “processing” nutrient molecules, capturing energy via the exchange of electrons, and converting that energy to ATP. The energy released from DNP action is converted into heat energy. Without ATP to provide energy, our bodies look to alternative sources like fat reserves. The overall result is an increase in the metabolic rate by a factor of 30% to 50%.

    You might wonder why the body does not use muscle as well as fat as an energy source (catabolism). One of the reasons lies with HSPs (Heat Shock Proteins). HSPs are known to maintain the shape and function of cellular proteins and promote muscle growth. HSPs go to work under circumstances where the body temperature increases, ATP is scarce, and free radicals are present. DNP does all of these things. Although some catabolism is likely to occur with DNP present, it follows that exercise combined with the release of HSPs result in the protection of muscle cells and promotion of protein synthesis.

    How is DNP Dangerous?

    1. DNP can kill you. We discussed how DNP converts the energy from food into heat energy, which increases body temperature. Unfortunately there is no limit to how high your body temperature can get while on DNP, so it can literally “cook” you.
    2. DNP can cause fever, stroke, nephritis, tachycardia, respiration problems, coma, and peripheral neuritis.
    3. DNP is a cumulative poison, meaning that it builds up in your system every day that you take it. It takes 3 weeks to evacuate your system and by the time you have a problem, it can be too late.
    4. DNP causes cataracts in 1 out of every 1,000 people.
    5. 10% of users develop and allergic reaction that includes hives, blisters, and rashes.
    6. Without ATP cells start to die.
    7. Free radicals cause cancer.
    8. The EPA, NTP, ASTDR, and WHO all categorize DNP as a category 1 toxic chemical.
    9. We do not really know how much cellular damage DNP causes.


    What are the benefits of DNP?

    1. Fat loss
    2. Anabolic rebound – After a DNP cycle the body is in a highly anabolic state.
    3. T3 reduction – If you happen to be running DNP right after an AAS
    4. cycle, the DNP can reduce the excessive T3 production that causes much of the
    5. catabolic type muscle loss post cycle.


    Note: DNP can lower T3 to below optimal levels, so in some cases it may be necessary to start taking small doses of T3.

    How should I take DNP?

    I have a conservative stance on when to use DNP, how much to use, and how long to use it.

    Some people argue that DNP should be used on cycle so as to protect muscle. My contention is that DNP makes you feel like crap, and it can detract from lifting at your best while on cycle. If I am on cycle I want to be lifting hard and I do not want to worry about energy levels or heat stroke.

    Other people argue that DNP should be used well after PCT. My only concern would be low energy levels and possible T3 issues. These concerns are manageable via things like ECA stacks and T3 supplementation.

    My most preferred time to run DNP is when I start PCT. I still have energy and strength from my cycle and I avoid the whole catabolic post cycle phase. In addition, I have a nice little anabolic rebound at the end of my DNP run and I get to see the results from all my hard work on gear.

    DNP is cumulative and it takes three weeks to clear your system. Do not bump up your dose because you think you can handle more. Do not use drugs or drink alcohol.

    Please note that you do not need to “feel” DNP for it to be working. People have different tolerance levels, even for poisons. You can only get so much DNP into your system (before you die), so you can choose to take a higher dose short cycle or lower dose long cycle. Regardless, by the end of the cycle you will feel the heat and toxicity.

    Low Dose Long Cycle

    Start with a dose of 200mg per day [100 mg every morning / 100 mg
    every evening]. Run it for two or three weeks.

    Day 1 – 14: 200 mg ED
    Day 15 – 21: 200 mg ED*

    *Experienced users may choose to run the cycle for an additional week.

    Total DNP consumption for long cycle: (2,800 to 4,200 mg)

    High Dose Short Cycle

    Start with a dose of 200 mg per day [100 mg every morning / 100 mg
    every evening]. Within 2 to 4 days you should know if you have an allergy.

    Day 1 – 4: 200 mg ED
    Day 5 – 9: 400 mg ED
    Day 10 – 11: 400 mg ED*

    *Experienced users may choose to go above the max recommended daily dose of 400 mg
    and run the cycle for an additional couple of days.

    Total DNP consumption for short cycle: (2,800 to 4,000 mg)

    What are common sides to DNP?

    • Discomfort and sweating
    • Insomnia
    • Yellow bodily fluids
    • Muscle Soreness
    • Allergic Reactions
    • Carbohydrate Cravings
    • Vomiting (a good sign that you should stop)


    What food and supplements should I take while on a DNP cycle?

    You may lose your senses of taste and smell so this is a good time to teach yourself how to eat without using condiments and all the other crap you dont need.

    • Water - One or two gallons a day. Dehydration is the leading cause of DNP problems, including death.
    • Fruit - Glycogen will be depleated. Fructose is good.
    • Protein - Diet should be heavy on protein.
    • Fiber - DNP can be rough so you may want to regulate (pun intended).
    • Complex Carbs - Carbs will make you hot. You should try to time your carb intake so that you are not eating carbs before workouts or before sleep.
    • Multi vitamin - You are likely to be on a rescticted diet and you will need to supplement.
    • Antioxidants - To stop the free radicals
    • Electolytes - V8 is good.
    • Melatonin - If necessary, to help you sleep.
    • ECA stack - If necessary, to boost your energy levels.


    Last edited by Presser; 01-31-2020 at 02:39 PM.
    Thanks SilkQuads, pgb, Beti ona thanked for this post
    Likes Presser, Iron Game, SilkQuads, pgb liked this post
     

  2. #2
    Presser's Avatar
    Join Date
    May 2002
    Posts
    41,686
    Rep Power
    2147525355

    Default

    pretty decent read for those considering using dnp, I personally would never use DNP. I stay nice and lean using IGF-1 Lr3 as long as money permits me to.

    Anyone who is considering using DNP, please exhaust all other options first! Insulin-like growth factor-1 Lr3 Is something you should really give a go. The IGF-1 lr3 tells your body to burn fat for energy. And of course it has many other positive attributes as its our main growth factor in the body when were developing as kids through adults.

    The IGF-1 lr3 is absolutely amazing!

    BUY IGF 1 Lr3 Here
    Last edited by Presser; 10-01-2019 at 10:54 AM.
    Thanks Bad Russian thanked for this post
     
    DNP and Fat Loss. DNP Cycle Dosages.

  3. #3
    Iron Game's Avatar
    Join Date
    Apr 2008
    Location
    MD
    Age
    51
    Posts
    5,060
    Rep Power
    2147488723

    Default

    Good read on DNP
    Likes Presser liked this post
     
    Your Character Is In Your DEEDS. Not Your Dreams!

    Follow Me twitter Iron-Game

  4. #4
    Presser's Avatar
    Join Date
    May 2002
    Posts
    41,686
    Rep Power
    2147525355

    Default

    DNP in Bloodstream for 30 days using 36 hour half-life

    Tracking your DNP dosage , even with continual dosage the rate of accumulation decreases as their is a peak for each DNP dose.

    Thanks Bad Russian thanked for this post
     
    DNP and Fat Loss. DNP Cycle Dosages.

  5. #5
    Iron Game's Avatar
    Join Date
    Apr 2008
    Location
    MD
    Age
    51
    Posts
    5,060
    Rep Power
    2147488723

    Default

    Thanks for this
    Likes Presser liked this post
     
    Your Character Is In Your DEEDS. Not Your Dreams!

    Follow Me twitter Iron-Game

  6. #6
    Presser's Avatar
    Join Date
    May 2002
    Posts
    41,686
    Rep Power
    2147525355

    Default

    Are you using dnp bro?
    DNP and Fat Loss. DNP Cycle Dosages.

  7. #7
    Iron Game's Avatar
    Join Date
    Apr 2008
    Location
    MD
    Age
    51
    Posts
    5,060
    Rep Power
    2147488723

    Default

    I know you hate DNP but yes. I'm on week 2.
    Last edited by Iron Game; 04-21-2016 at 08:52 PM.
    Thanks Presser thanked for this post
    Likes Presser liked this post
     
    Your Character Is In Your DEEDS. Not Your Dreams!

    Follow Me twitter Iron-Game

  8. #8
    Presser's Avatar
    Join Date
    May 2002
    Posts
    41,686
    Rep Power
    2147525355

    Default

    DNP for Dummies:

    DNP has some painful results, so do not jump for DNP out of curiosity, or without the needed will power to operate this responsibly. So here are my experienced guidelines to using it the RIGHT way.

    FIRST GUIDLINE:
    Dosing. Use ONLY (200mg for men) and (100mg for women) a day for the first four days. Who cares that you don't "feel" anything yet and you wanna bump it up. DNP accumulates in the body, and not "feeling" something means NOTHING. It's there, and it's working (the effect on metabolism begins within two hours of the first dose!). Four days will let you test your tolerance: do you have an allergy? Does it give you a rash? etc.

    Only after those four days do you bump it up, by 200mg a day. The average dose is 400-600/ day, and more than that gets a little severe. A full gram is the highest dose anyone use. Stay around 600 a day, which is HOT but safe and effective. Take caps even hours apart through the day, ending about 4-5 PM.

    SECOND GUIDLINE:
    How to eat on DNP. This is purely personal experience, because some guys like to carb-deplete *before* using DNP (then eat carbs as usual while on), and other guys like a low-carb approach throughout. Both are fine. Using DNP is the only time that fructose is a desireable cutting carb, because it keeps the liver replentished. That reduces lethargy and spares muscle.

    Be aware that eating high-carb foods WILL increase the heat sensation within an hour, and last about 2 hours. That means don't eat carbs before bed unless you want those night sweats to be even WORSE. SOME GUYS ate whatever they wanted! IHOP, chinese, fajitas...Yes, it burned hot, but u will still be able to loose 1.5 pounds every 2 days. Keep protein HIGH for muscles' sake, and try it yourself (on your own risk).

    Suggested food:
    Blueberry yogurt. Blueberries are excellent antioxidants, and yogurt cultures help with digestive function, gas, and stool consistency (disgustingly soft stools are common during DNP).
    Oregano-based foods. Oregano is perhaps one of the most potent antioxidants around, and one spoonful counts as a vegetable serving. Pineapple - I've found that pineapple helps alleviate those "DNP Blues". The fructose helps, and pineapple enzymes aid in protein digestion.

    Oatmeal - high-fiber foods are necessary. You'll find out why around, oh, day 5 or so. Trust that.
    THIRD GUIDELINE:
    Suggested supplements with DNP:
    ECA - DNP is not a stimulant. To keep energy high and aid in fat loss, use an ECA. Some advisors suggest that regular ephedrine is preferable to norephedrine because of the more direct "hit" of energy.
    Prohormones - perfectly fine on DNP. Just to help keep strength and muscle up, and it worked fine. No problems here. You won't GROW muscle on DNP, but it'll help with strength and protection.
    Obvious stuff - multivitamin, ZMA, etc.
    A pre-workout mixture with low-carb, so it won't cause carb-heat in the middle of your workout.

    Antioxidants - and why to use them:
    - Alpha Lipoic Acid - aids in fat management and blood sugar, and an excellent antioxidant.
    - Grape seed extract
    - Green Tea
    - Fruit antioxidants
    - Trimethylglyceine - antioxidant, helps move fat and blood lipids into the liver and out of the body. 500mg, 2-4x day.
    - Vitamins E and C (multivatamin tabs are good as well)

    Supplements NOT to use:
    Any medications that suppress energy. No allergy meds, antidepressants, muscle relaxers, or beta blockers. DNP will have you low as it is; don't worsen your body's energy by taking something that suppresses you further.
    DRUGS - NO alcohol (not even "moderate"), NO ecstasy, NO GHB, etc. If you don't have the willpower to forget these habits, DNP is not for you.

    FOURTH GUIDELINE:
    Working out on DNP. Keep lifting short, 30-40 minutes. DNP works very well, causing your body to use 150% of the calories per action you'd normally use. That means DON'T try to repeat your usual workouts. Drop to moderate weights, 8-12 reps, not to failure, and with plenty of walking rest between sets. You are NOT going to grow muscle on DNP, so don't use your usual heavy routine. Since DNP can cause light-headedness and heat dizzyness, you have my permission to skip squats in favor of leg presses this time.

    Cardio is a controversial one. (ADVICE) - do NOT do cardio on high doses of DNP (600mg or more). It's dangerous and counterproductive. Below that amount, some cardio is fine, but keep it to 20 minutes and not at full-gallop. Remember, DNP will drain water from your body quickly, causing you to leech out minerals, vitamins, and salts. Don't overdo it.

    During exercise, consume at least 1 liter of water per 30 minutes of work, whether you're thirsty or not. DNP is evil in the way it blunts thirst, while at the same time doing the cruel trick of bloating your body with water WHILE dehydrating you from water in your organs. MAKE yourself drink. Always folllow DNP exercise with antioxidants, carbs, and this is a good time to use your multivitamin.

    Don't feel embarrassed about poor workouts. Listen to your body, and let it tell you when enough's enough; don't gauge workouts by what you *usually* can do otherwise.

    This product will Burn fat, lose weight, reduce fat, boost metabolism, lose fat, lose weight and Accelerate your metabolism safely.

    Likes NAIR liked this post
     
    DNP and Fat Loss. DNP Cycle Dosages.

  9. #9
    MuscleChemistry Newbie Residency Training

    Join Date
    Apr 2016
    Posts
    21
    Rep Power
    0

    Default

    DNP is by far my favorite for cutting. People seem scared to use it but if used right there is nothing wrong with it. I've ran quite a decent number of cycles on this stuff and what works best for me and what I tell my buddies to run it at is as follows.

    Days 1-4 250mg
    Days 5-10 500mg
    Days 11-14 250mg

    It's so simple yet so effective. I've also noticed taking it right before bed seems to work the best for me and my guys. You're not as lethargic throughout the day because the highest peak from that dose hits while your asleep. You wake up stupid thirsty but I always have to get up to pee in the middle of the night 1 to 2 times and will just chug down some water and back to bed.

    Staying hydrated is so important, I was at 2 to 3 gallons of water per day during my runs. You really just don't ever feel like you can quench your thirst!

    Sent from my SAMSUNG-SM-N910A using Tapatalk
    Thanks Presser thanked for this post
    Likes Presser, Iron Game liked this post
     

  10. #10
    Presser's Avatar
    Join Date
    May 2002
    Posts
    41,686
    Rep Power
    2147525355

    Default

    Quote Originally Posted by Akhusker View Post
    DNP is by far my favorite for cutting. People seem scared to use it but if used right there is nothing wrong with it. I've ran quite a decent number of cycles on this stuff and what works best for me and what I tell my buddies to run it at is as follows.

    Days 1-4 250mg
    Days 5-10 500mg
    Days 11-14 250mg

    It's so simple yet so effective. I've also noticed taking it right before bed seems to work the best for me and my guys. You're not as lethargic throughout the day because the highest peak from that dose hits while your asleep. You wake up stupid thirsty but I always have to get up to pee in the middle of the night 1 to 2 times and will just chug down some water and back to bed.

    Staying hydrated is so important, I was at 2 to 3 gallons of water per day during my runs. You really just don't ever feel like you can quench your thirst!

    Sent from my SAMSUNG-SM-N910A using Tapatalk
    yeah I'm one of those guys who rails against using dnp, the risk reward just doesn't make sense to me plus you can get shredded as fuck with plenty other things but to each their own .
    DNP and Fat Loss. DNP Cycle Dosages.

  11. #11
    Presser's Avatar
    Join Date
    May 2002
    Posts
    41,686
    Rep Power
    2147525355

    Default

    Just read another guy was being sentenced this week or last week for selling DNP online i think, and someone died and they tracked the DNP source down.

    I know some of you use this shit, but I wouldnt go near it ever!
    DNP and Fat Loss. DNP Cycle Dosages.

  12. #12
    MuscleChemistry Guru Board Certified CPH
    Dean Destructo's Avatar
    Join Date
    May 2016
    Posts
    1,279
    Rep Power
    2147484934

    Default

    Quote Originally Posted by Presser View Post
    Just read another guy was being sentenced this week or last week for selling DNP online i think, and someone died and they tracked the DNP source down.

    I know some of you use this shit, but I wouldnt go near it ever!
    Exactly. Some types of rat poison will have the same effect as well. Strychnine comes to mind, it was used in earlier bike races to increase performance.
    Thanks Presser thanked for this post
    Likes Presser liked this post
     

  13. #13
    Presser's Avatar
    Join Date
    May 2002
    Posts
    41,686
    Rep Power
    2147525355

    Default

    Quote Originally Posted by Dean Destructo View Post
    Exactly. Some types of rat poison will have the same effect as well. Strychnine comes to mind, it was used in earlier bike races to increase performance.

    rat poison in bike racing competition, sounds so fitting considering all the fucking RATS in the cycling world! Yeah im talking about Lance Armstrong era lol.

    YOU down with DNP? Yeah you know me! ....nope!

    I know , presser you gay ass! lol anyhow, loads of DNP searches hitting MuscleChemistry and i figured i would bump this so maybe we can save half of you from dropping dead
    DNP and Fat Loss. DNP Cycle Dosages.

  14. #14
    MuscleChemistry Newbie Board Certified Psy.D

    Join Date
    Sep 2016
    Posts
    76
    Rep Power
    155

    Default

    did you carb deplete for the 1st 3 days? i am on my 3rd week at 400mg. i tried 600mgs, but it was too much for me!
    Thanks Presser thanked for this post
    Likes Presser liked this post
     

  15. #15
    Presser's Avatar
    Join Date
    May 2002
    Posts
    41,686
    Rep Power
    2147525355

    Default

    Quote Originally Posted by Husky1 View Post
    did you carb deplete for the 1st 3 days? i am on my 3rd week at 400mg. i tried 600mgs, but it was too much for me!

    bumping to the top for Husky1's question about carb depleting the first 3 days, and i have never used DNP, so wish i could help ya daddio!
    DNP and Fat Loss. DNP Cycle Dosages.

  16. #16
    Iron Game's Avatar
    Join Date
    Apr 2008
    Location
    MD
    Age
    51
    Posts
    5,060
    Rep Power
    2147488723

    Default

    Great article on DNP cycle
    Your Character Is In Your DEEDS. Not Your Dreams!

    Follow Me twitter Iron-Game

  17. #17
    MuscleChemistry Junior Member Board Certified Psy.D
    Area 1255's Avatar
    Join Date
    Sep 2014
    Posts
    285
    Rep Power
    2147483942

    Default

    DNP has been coming up more and more lately, but it definitely is not something to play around and "estimate" doses with! I think that's a big problem with those who provide it in powder form. Still, accountability is primarily in the users hands, especially when you see shit like Tianeptine overdoses happening.
    Area-1255;"the last of the honest bloggers".
    Well-versed in Pharmacology/Pharmacodynamics, Computer Security, Strength Training, and...The Craziest Push-Ups you've Never Seen

  18. #18
    Presser's Avatar
    Join Date
    May 2002
    Posts
    41,686
    Rep Power
    2147525355

    Default

    I see less and less talk about DNp and all the how to take it questions. Thankfully lol

    we still see the Where can I buy dnp questions though lol
    DNP and Fat Loss. DNP Cycle Dosages.

  19. #19
    Musclechemistry Board Certified Member Board Certified MD
    drtbear1967's Avatar
    Join Date
    Aug 2016
    Location
    Kentucky
    Posts
    5,663
    Rep Power
    2147489318

    Default

    If you don't know the deal with DNP, You don't need to play with it.
    Likes Presser, pgb liked this post
     
    Get It Done!

  20. #20
    Presser's Avatar
    Join Date
    May 2002
    Posts
    41,686
    Rep Power
    2147525355

    Default

    Quote Originally Posted by drtbear1967 View Post
    If you don't know the deal with DNP, You don't need to play with it.
    Where or what forum did you post that article on new DNP safer alternative ? I want to copy the article here or at least the link to it
    Likes anomily88 liked this post
     
    DNP and Fat Loss. DNP Cycle Dosages.

  21. #21
    Presser's Avatar
    Join Date
    May 2002
    Posts
    41,686
    Rep Power
    2147525355

    Default

    BUMPING dor drtbear, and again. FUCK DNP !
    Likes pgb, Maj7900 liked this post
     
    DNP and Fat Loss. DNP Cycle Dosages.

  22. #22
    MuscleChemistry Registered Member Board Certified MD
    NAIR's Avatar
    Join Date
    Jun 2006
    Location
    Somewhere over the rainbow
    Posts
    4,742
    Rep Power
    3768116

    Default

    Admittedly I'd like to try this stuff. What's this DNP alternative though?
    Thanks Presser thanked for this post
    Likes Presser, anomily88 liked this post
     

  23. #23
    MuscleChemistry Guru Board Certified DMD
    Maj7900's Avatar
    Join Date
    Feb 2018
    Posts
    659
    Rep Power
    2147484313

    Default

    Quote Originally Posted by NAIR View Post
    Admittedly I'd like to try this stuff. What's this DNP alternative though?
    I’ve done DNP once. Some like it because it works but no one will deny that it’s a rough road. I did 20 days at 200mg a day and yes it dropped weight and I did this right through thanksgiving (on purpose) just to see. It’s going to lite you up for eating carbs....it will lite you up period. The summer time is not a good idea in my opinion due to overheating. It’s not a tren overheating this is more of like a thermal nuclear meltdown. Some will get itchy and rashes but in that case just stop using it. This happens every so offen and usually only once per the user but this is all subjective to your body. It’s a poison that cranks up your heat and melts Fat away.

    I’m strictly to T3 now...lol


    Team MeccaGear!
    Likes gandhisays, NAIR liked this post
     

  24. #24
    Musclechemistry Board Certified Member Board Certified MD
    drtbear1967's Avatar
    Join Date
    Aug 2016
    Location
    Kentucky
    Posts
    5,663
    Rep Power
    2147489318

    Default

    It's that time of the year again. Be safe and know what you are doing.
    Likes Maj7900, gandhisays liked this post
     
    Get It Done!

  25. #25
    Stage Pro Board Certified MD
    gandhisays's Avatar
    Join Date
    Dec 2008
    Posts
    8,927
    Rep Power
    2147492590

    Default




    2,4-Dinitrophenol is a toxic dye, chemically related to trinitrophenol (picric acid), used in biochemical studies of oxidative processes where it uncouples oxidative phosphorylation. It is also used as a metabolic stimulant.
    2,4-Dinitrophenol is used in the manufacture of dyes, wood preservatives, and as a pesticide. The acute (short-term) effects of 2,4-dinitrophenol in humans through oral exposure are nausea, vomiting, sweating, dizziness, headaches, and loss of weight. Chronic (long-term) oral exposure to 2,4-dinitrophenol in humans has resulted in the formation of cataracts and skin lesions, weight loss, and has caused effects on the bone marrow, central nervous system (CNS), and cardiovascular system. Limited or no information is available on the developmental, reproductive, or carcinogenic effects of 2,4-dinitrophenol in humans. EPA has not classified 2,4-dinitrophenol for carcinogenicity.


    2,4-DINITROPHENOL is a solid yellow crystals. Explosive when dry or with less than 15% water. The primary hazard is from blast of an instantaneous explosion and not flying projectiles and fragments. slightly soluble in water and soluble in ether and solutions of sodium or potassium hydroxide.
     

  26. #26
    Stage Pro Board Certified MD
    gandhisays's Avatar
    Join Date
    Dec 2008
    Posts
    8,927
    Rep Power
    2147492590

    Default

    I havent used dnp so i am not real world experienced with it.my question is do those who do take dnp use the "wetted dnp" or the analytical standard pestanal.

    i was wonderin how much dnp cost cause its so so dangerous but still very popular.so i think maybe the low cost associated with dnp could be why.afterlooking up the cost of dnp from a chemical company i realized how cheap it was to buy no matter if buoght wetted dnp which is $100 U.S. for a kilogram and still cheap even when buying the analytical standard which cost something like $50 U.S for 250mg

    the price difference is whacky. so what is taken? wet or analytical standard? i bet some of the blokes that sell dnp will still cut it with something biologically benign even though its dirt cheap regardless of which they get.

    my personal opinion is if you need to use dnp your not training or eating properly.
    Likes Maj7900 liked this post
     

  27. #27
    MuscleChemistry Registered Member Board Certified MD
    NAIR's Avatar
    Join Date
    Jun 2006
    Location
    Somewhere over the rainbow
    Posts
    4,742
    Rep Power
    3768116

    Default

    I have not ruled out trying DNP. I do wonder about this new alternative Presser mentioned a few posts up though.
    Likes Presser, Maj7900 liked this post
     

  28. #28
    MuscleChemistry Guru Board Certified DMD
    Maj7900's Avatar
    Join Date
    Feb 2018
    Posts
    659
    Rep Power
    2147484313

    Default

    Quote Originally Posted by gandhisays View Post
    I havent used dnp so i am not real world experienced with it.my question is do those who do take dnp use the "wetted dnp" or the analytical standard pestanal.

    i was wonderin how much dnp cost cause its so so dangerous but still very popular.so i think maybe the low cost associated with dnp could be why.afterlooking up the cost of dnp from a chemical company i realized how cheap it was to buy no matter if buoght wetted dnp which is $100 U.S. for a kilogram and still cheap even when buying the analytical standard which cost something like $50 U.S for 250mg

    the price difference is whacky. so what is taken? wet or analytical standard? i bet some of the blokes that sell dnp will still cut it with something biologically benign even though its dirt cheap regardless of which they get.

    my personal opinion is if you need to use dnp your not training or eating properly.
    Last statement is on point. Well...the whole thing really but, the last is important. I’ve got 70 pills of death left in my drawer for when hell freezes over. Clem and T3 but other than that low fat with the right mix of carbs is the way to go. Igf/HGH/Frag and even M2 are options but these are for a polish off not to drop 4%.


    Team MeccaGear!
    Likes Presser, drtbear1967 liked this post
     

  29. #29
    Presser's Avatar
    Join Date
    May 2002
    Posts
    41,686
    Rep Power
    2147525355

    Default

    I concur
    DNP and Fat Loss. DNP Cycle Dosages.

  30. #30
    MuscleChemistry Guru Board Certified DMD
    Maj7900's Avatar
    Join Date
    Feb 2018
    Posts
    659
    Rep Power
    2147484313

    Default

    Quote Originally Posted by NAIR View Post
    I have not ruled out trying DNP. I do wonder about this new alternative Presser mentioned a few posts up though.
    I’m not sure about the new option but I’d try it over DNP. What is the new option you’re speaking of?


    Team MeccaGear!
     

  31. #31
    MuscleChemistry Registered Member Board Certified MD
    NAIR's Avatar
    Join Date
    Jun 2006
    Location
    Somewhere over the rainbow
    Posts
    4,742
    Rep Power
    3768116

    Default

    Agreed, fellas. I too often do not eating properly. I'm working on it.
     

  32. #32
    MuscleChemistry Guru Board Certified CPH
    yellow snow's Avatar
    Join Date
    Jun 2015
    Posts
    1,835
    Rep Power
    2147485491

    Default

    I have tried DNP on numerous occasions. It is poison and will never use it again; it is not worth it long term and you can do what DNP does if you do a keto based diet.

    We all know that there is no "easy" button, DNP is enticing but too dangerous!!
    Likes big in vegas liked this post
     
    Beach bodies are made in the winter.

  33. #33
    MuscleChemistry Registered Member Board Certified MD
    big in vegas's Avatar
    Join Date
    Jul 2010
    Location
    Hell
    Posts
    18,534
    Rep Power
    2147502195

    Default DNP

    Phase 1:

    The 3-day Carb-Depletion Phase.

    Phase 2:


    The 1-day Thyroxine (T3) Re-normalization Phase.


    Phase 3:

    The 14-day DNP Phase.
    Phase 4:
    The 2-day Post-DNP Phase.


    7-day DNP fat loss plan involves a moderate to high dosage of DNP for fat burning. The DNP fat loss plan involves a 7-day on, 7-day off approach with four distinct phases. Most athletes using DNP follow this type of cycle. The phases are as follows:













    Phase 1. The 3-day Carb-depletion phase
    Phase One has a three-day duration and begins the four days preceding the ingestion of DNP. The purpose of this phase is to deplete muscle-glycogen content by restricting carbohydrates. This is achieved through a Ketogenic style diet.

    Kcals should be restricted to 10-12 times bodyweight in lbs. And carbohydrates should be restricted to less than 60g/day. Protein is consumed at 1 gram per pound of bodyweight or higher and the remaining dietary calories should come from fat.

    This phase lasts exactly 3 days, and will reduce muscle-glycogen levels so that the body is forced to rely on fat as fuel more readily when you start your DNP cycle.

    Phase 2 The 1-day Thyroxine (T3) Re-normalization Phase
    This is a new concept for DNP dieting. During the past three days, the athlete has restricted carbohydrates and as a direct consequence T4-T3 conversion is slowed down resulting in reduced T3 levels. This is bad for the DNP phase, as you need enough active T3 to last throughout the entire 7-day on DNP phase.

    Day four of the DNP cycle involves a mega-carbohydrate meal at mid-afternoon (4-6PM) designed to create a massive insulin spike and re-normalize T4-T3. This concept has been extrapolated from ketogenic diets and has been shown to dramatically increase serum concentrations of T3.

    Day 4 involves Keto eating until the Mega-carb meal. Then in the late afternoon, at least circa 250g of carbohydrates must be consumed to create an insulin spike. Any sugar (fructose, sucrose, maltose etc.) is fair game. Fructose in particular is good because it primarily re-fills liver glycogen which is directly involved in T4-T3 conversion. (Empty liver glycogen signals the thyroid to decrease T4-T3 conversion).

    As a side-note, a 250g carb-meal after three days of Keto dieting creates a more pronounced insulin spike than would a 250g carb-meal after three days of normal eating.

    Kcals during Phase 2 should be kept at 15X Bodyweight in lbs. Macro-nutrient break-downs can be calculated by the athlete. The only carb intake on day 4 should be the 250g carb-meal.

    Phase 3 The 14-Day DNP Phase

    The first two days of actual DNP consumption are the most important to follow correctly. During Days 1 and 2 of the actual DNP portion of the cycle, it must be determined if the athlete will have an allergic reaction to DNP.

    Day 1: 200 mg of DNP is ingested
    Day 2: 200 mg of DNP is ingested

    At this point the dieter should be able to assess if an allergic reaction has occurred. A DNP-stimulated allergic reaction will lead to swelling in as little as 1 to 2 days time. Approximately 10% of athletes will have such a reaction. The unfortunate few who experience this type of a reaction must terminate the cycle immediately. Benadryl or Ketotifen (Anti-histamines) can be used to treat mild symptoms. Obviously a doctor should be consulted should the symptoms prove more severe.

    Day 3: Dieters making it to day 3 of the DNP phase have the option of increasing their dosage. The normal dosage for beginners is 400mg DNP/day. Even an amount this small should provide outstanding results. A word of caution. DO NOT TAKE MORE, if you are not experienced with DNP-use. More advanced users may chose to go higher based on past experience.
    The 400mg/day dosage is maintained from Day 3 through Day 9(Exactly 7 days). The last dose is taken on Day 9.

    Supplementation and Nutritional Protocol for a DNP cycle:

    1. An ECA stack is beneficial while on a DNP cycle as it as it acts as an anorectant. DNP raises Neuro-peptide Y levels in the brain, which is directly linked to increased hunger. Consuming 75-100mg total of ephedrine alkaloids/day should be sufficient to suppress appetite. PPA (Nor-ephedrine) should NOT be used as it causes lethargy when combined with DNP.

    2. Anti-oxidants. Due to the DNP induced rapid combustion of fats, free-radical production skyrockets up-wards. To combat this, anti-oxidants must be used. Anti-oxidants are the single most important supplement to take on a DNP cycle.

    a) Fat-soluble Anti-O: Vitamin E: 1000mgs/day
    b) Water-soluble Anti-O: Vitamin C: 2-3g/day
    c) Alpha Lipoic acid: 600-1000mgs/day

    Dual-anti-oxidant: BOTH fat & water-soluble actually re-cycles other anti-oxidants.

    3. Glycerol: Although optional, glycerol is often consumed at 15ml's 3X/day. Glycerol increases hydration for many athletes.
    No additional supplements are really required other than these three. All the rest you have read in various DNP articles are more for peace of mind than improved functionality. I consider them overkill.

    4. Water: Not a supplement, but an absolute necessity.
    DNP causes sweating and can be incredibly dehydrating. Dehydration is the NUMBER ONE cause of most DNP problems and deaths. Excessive dehydration results in over-heating. Dieters who do not replenish fluids properly while on a DNP cycle could die. The consensus among athletes is that at least two gallons of water must be consumed daily.

    5. EAT FRUIT while on your DNP cycle.

    Fruit for some reason has been found to greatly reduce the lethargy associated with a DNP cycle. It also has a high water content, therefore it helps to keep the dieter hydrated. Watermelon is an obvious recommendation.

    6. Dietary intake: There are several schools of thought on this matter, but sticking to the old standard always works.
    Kcals should be kept anywhere from 10-15X Bodyweight in lbs. Macro-nutrient break-downs should be kept at around 20% fat, 30% protein and 50% carbs. (Changing the ratios in favor of more carbs and protein w/ less fat will result in a more fat loss but nothing special. Also, remember that more carbohydrates means more heat.)

    Take for example the 220 lb (100 kg) bodybuilder. He would consume anywhere from 2200 to 3300Kcal /day (Depending on his appetite control).

    WHAT NOT TO DO on a DNP cycle.

    a) Do not under any circumstances consume alcohol or ANY type of diuretic while on a DNP cycle. Alcohol and diuretics will dehydrate you and can cause SERIOUS problems.
    b) Do not remain in a hot environment without replenishing fluid loss due to perspiration. This too can also cause SERIOUS problems.
    c) Do not begin with a high dosage of DNP if you are a novice. This is just asking for a trip to the ICU.

    The half-life of 2,4 Dinitrophenol is 36 hours. So, after 36 hours, there is only 50% of the DNP remaining in your system. Therefore, 72 hours later 25% remains. Then 12.5% remains after 108 hours. After 5 days (120 hours), there's roughly 9% of the DNP left in your body that you had on Day 9. This DNP concentration is low-enough to allow you to begin Phase 4 of the cycle -- the 2-day Post-DNP phase -- without compromising glycogen synthesis rates. Kcals during Days 10-14 should remain the same as during days 3-9.

    Phase 4: The 2 day Post DNP Phase.

    The whole purpose of this phase is to get muscle-glycogen levels back to normal. The Ketogenic carb-up can be used as a sort of template for this phase.

    After Phases two and three, muscle-glycogen levels are depressed and need to be replenished.

    Day 15: Carb-intake should be 7g/Kg of LBM (lean body mass = bodyweight minus body fat.) So assuming a 220 lb bodybuilder has 0% body fat, lol, he would consume 700 g of Carbs. Protein-intake remains at 1g/lb and fat is restricted as low as possible.
    The focus on day 1 should be on High-GI foods like Fat-free Ice-cream and all the other non-fat high sugar desserts. Calories should be around 4000 for the 220-lb bodybuilder -- in other words, 18X bodyweight in lbs.

    Drastically restricting fat is CRITICAL here, as the body is still burning fat for fuel as you replenish your glycogen stores. In essence, the dieter is still losing fat while carbing up.

    Day 16: Muscle-glycogen has increased, so carb-intake should be decreased from day one’s 7g/Kg to only 5g/Kg of LBM. That would be 500g for our 220-lb bodybuilder. Protein is 1g/lb again. Fat remains as low as possible. Kcals for the dieter are reduced to 3000 Kcal range, or around 14X Bodyweight in lbs. The focus of Day 2 should be low-GI foods like vegetables, milk, lean meats etc.

    Additional Precautions:

    Dieters feeling extremely nauseated or who vomit during a cycle should discontinue use immediately and not restart for at least 36 hours.

    Dieters should carry a pocket thermometer at all times. If body temperature rises above 102 Fahrenheit then the dosage should be lowered or the cycles should be terminated. Additionally, the dieter should take a very cold bath to lower the temperature.
    In addition to water, V8 juice should be consumed. Drinking gallons of water depletes the body of electrolytes pretty badly predisposing the dieter to shock, nausea, lethargy, and even death. V8 is the best for replenishing electrolytes as it contains 950mg of potassium per 8oz compared to Gatorade’s 35mg of potassium in 8oz.

    Massive amounts of fruits and sweets should be consumed if one becomes nauseated or vomits – i.e. force feed yourself.
    Dieters should never allow themselves to become overheated on a DNP cycle. Always stay next to a fan and keep the air conditioner on. Do not attempt a DNP cycle if you work out doors in a warm climate or another warm environment like a kitchen. Even at low doses this can build up and be potentially dangerous.

    There are two versions of DNP – regular and crystalline. Know which one you are taking. When taking the crystalline DNP caps, never take more than 200mg at once if you've never used it before. Even if you are used to it, it is still much safer to spread the dosage throughout the day. Crystalline DNP is much faster acting and can rapidly elevate temperature.

    Post-Steroid Cycle Use of DNP

    One of the primary causes of muscle breakdown after a steroid cycle is suppressed TSH. Anabolic steroids suppress TSH, which in turn lowers T3 and T4 production by the thyroid gland. The reduction in TSH is one reason that anabolic steroids are such excellent muscle builders.

    Soon after the completion of a steroid cycle, TSH up-regulates, which in turn super-stimulates the thyroid. This excess stimulation causes the thyroid to produce above normal levels of T3 and T4. This increase in thyroid hormones is highly catabolic and is the main reason why people lose muscle post-cycle.

    Athletes have learned that they need to restrict T3 production post cycle to prevent muscle loss. A novel approach to achieving this goal is the use of DNP. About 80% of the body’s endogenous T3 is produced from the metabolically inactive T4 to the metabolically active T3. The de-iodinase enzyme is responsible for this conversion. It literally cleaves off an iodine molecule.
    By ingesting 200mg DNP/day, the athlete can correct the over stimulated Thyroid, returning T3 levels back to normal. DNP directly blocks the production of T3 from T4 via the de-iodinase enzyme.

    As a bonus, the reduction in your ATP stores because of the DNP is counter acted by an increase in the oxidation of triglycerides as an energy source. The benefit is the elimination of any potential fat-gain from the low post-cycle testosterone levels. And as DNP is non-hormonal, it has no effect on HPTA recovery.


    "Pissing excellence and shitting perfection."

  34. #34
    MuscleChemistry Registered Member Board Certified MD
    big in vegas's Avatar
    Join Date
    Jul 2010
    Location
    Hell
    Posts
    18,534
    Rep Power
    2147502195

    "Pissing excellence and shitting perfection."

  35. #35
    Presser's Avatar
    Join Date
    May 2002
    Posts
    41,686
    Rep Power
    2147525355

    Default

    Quote Originally Posted by Presser View Post
    pretty decent read for those considering using dnp, I personally would never use DNP. I stay nice and lean using IGF-1 Lr3 as long as money permits me to.

    Anyone who is considering using DNP, please exhaust all other options first! Insulin-like growth factor-1 Lr3 Is something you should really give a go. The IGF-1 lr3 tells your body to burn fat for energy. And of course it has many other positive attributes as its our main growth factor in the body when were developing as kids through adults.

    The IGF-1 lr3 is absolutely amazing!

    BUY IGF 1 Lr3 Here

    Still the best option out there!

    BUY IGF 1 Lr3 Here
    DNP and Fat Loss. DNP Cycle Dosages.

  36. #36
    Musclechemistry Board Certified Member Board Certified MD
    drtbear1967's Avatar
    Join Date
    Aug 2016
    Location
    Kentucky
    Posts
    5,663
    Rep Power
    2147489318

    Default

    DNP is not for the beginner.
    Thanks anomily88 thanked for this post
    Likes anomily88 liked this post
     
    Get It Done!

  37. #37
    MuscleChemistry Newbie Residency Training

    Join Date
    Dec 2018
    Posts
    13
    Rep Power
    0

    Default

    Thinking of doing 150mgs a day DNP
    20mgs a day phentermine for 75 days while hitting gym daily I am on T.R.T and will be taking Nac and Taurine also daily electrolytes keeping protien up carbs and calories down

    Sent from my SM-N950U using Tapatalk
    Thanks Presser thanked for this post
    Likes Presser liked this post
     

  38. #38
    Musclechemistry Board Certified Member Board Certified MD
    drtbear1967's Avatar
    Join Date
    Aug 2016
    Location
    Kentucky
    Posts
    5,663
    Rep Power
    2147489318

    Default

    Keep us in the loop as to how it goes.
    Get It Done!

  39. #39

  40. #40
    Presser's Avatar
    Join Date
    May 2002
    Posts
    41,686
    Rep Power
    2147525355

    Default

    Quote Originally Posted by anomily88 View Post
    Thinking of doing 150mgs a day DNP
    20mgs a day phentermine for 75 days while hitting gym daily I am on T.R.T and will be taking Nac and Taurine also daily electrolytes keeping protien up carbs and calories down

    Sent from my SM-N950U using Tapatalk
    Did you ever wind up using DNP? I dont think i have ever heard of anyone using DNP alonside phentermine , that does NOT sound Healthy to me! DNP in and of itself doesnt sound healthy to me and i would never use it personally but man if i did, i surely dont think my body could take it with phentermine
    Thanks anomily88 thanked for this post
    Likes anomily88 liked this post
     
    DNP and Fat Loss. DNP Cycle Dosages.

  41. #41
    MuscleChemistry Newbie Residency Training

    Join Date
    Dec 2018
    Posts
    13
    Rep Power
    0

    Default

    Quote Originally Posted by Presser View Post
    Did you ever wind up using DNP? I dont think i have ever heard of anyone using DNP alonside phentermine , that does NOT sound Healthy to me! DNP in and of itself doesnt sound healthy to me and i would never use it personally but man if i did, i surely dont think my body could take it with phentermine
    Yes I did for 3 months was fine its not healthy but my body don't burn fat normally and I have a huge appetite even after I eat I am never fulfilled its a problem myself and doctors are trying to fix atkins diet is not healthy either all that meat plug arteries I stick to vegan diet now and am doing alot better now on that 90 day cycle I was cheating and a fast way to my goals I dont wanna sugar coat anything

    Sent from my SM-N950U using Tapatalk
     

  42. #42
    Musclechemistry Board Certified Member Board Certified MD
    drtbear1967's Avatar
    Join Date
    Aug 2016
    Location
    Kentucky
    Posts
    5,663
    Rep Power
    2147489318

    Default

    bump
    Get It Done!

  43. #43
    Presser's Avatar
    Join Date
    May 2002
    Posts
    41,686
    Rep Power
    2147525355

    Default

    Quote Originally Posted by anomily88 View Post
    Yes I did for 3 months was fine its not healthy but my body don't burn fat normally and I have a huge appetite even after I eat I am never fulfilled its a problem myself and doctors are trying to fix atkins diet is not healthy either all that meat plug arteries I stick to vegan diet now and am doing alot better now on that 90 day cycle I was cheating and a fast way to my goals I dont wanna sugar coat anything

    Sent from my SM-N950U using Tapatalk
    Talk about honesty! Love the no sugar coating! As for this DNP thread, i see it getting read a lot lately and just think its important to say....stay away from this BS
    DNP and Fat Loss. DNP Cycle Dosages.

  44. #44
    Presser's Avatar
    Join Date
    May 2002
    Posts
    41,686
    Rep Power
    2147525355

    Default

    DNP and Fat Loss. DNP Cycle Dosages.

Similar Threads

  1. Steroid Cycle Post cycle therapy (PCT). PCT Protocol and Dosages Information
    By Presser in forum Bodybuilding Steroid & Training Articles
    Replies: 11
    Last Post: 11-14-2023, 04:35 PM
  2. Dianabol Cycle. Dbol Cycle Dosages and Side Effects
    By Presser in forum Bodybuilding Steroid & Training Articles
    Replies: 10
    Last Post: 01-10-2016, 11:37 AM
  3. small dosages of T4 while on a huge cycle
    By Arabian_Freak in forum MuscleChemistry Discussion
    Replies: 2
    Last Post: 04-27-2004, 04:48 PM
  4. drol dosages and cycle critiq.
    By peterhead in forum MuscleChemistry Discussion
    Replies: 10
    Last Post: 08-06-2003, 08:39 AM
  5. Clomid dosages after test cycle
    By bullcocky in forum MuscleChemistry Discussion
    Replies: 6
    Last Post: 01-24-2003, 05:14 PM

Tags for this Thread

Posting Permissions

  • You may not post new threads
  • You may not post replies
  • You may not post attachments
  • You may not edit your posts
  •  

Log in

Log in