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    Default Winstrol Cycle - Winsrol Stanozolol Cycle with Testosterone

    Winstrol Cycle - Winsrol Stanozolol Cycle with Testosterone

    Aside from testosterone, Winstrol (stanozolol) is the most popular steroid on the market. A Winstrol cycle is popular because it is often used in cutting cycles. You have bodybuilders using it before a contest, and you have regular gym goes using it while dieting to improve their physical appearance and/or get ready for summer. On top of that, it is an oral steroid, which is often preferred by the average steroid user, who does not want to use needles.As mentioned earlier, testosterone is more times than not, the base of every steroid cycle. It helps improve your overall feeling, energy, libido, build muscle, and more. But because of frequent injections, possible water retention, estrogen, and other potential side effects, some new steroid users stay clear of testosterone, and injections in general... thus we have the Winstrol cycle.The problem with a Winstrol cycle is that it has more side effects than testosterone. The difference is(besides the injections), testosterone's side effects are often visual, gynecomastia(bitch tits), acne, water retention etc. On the other hand you have Winstrol, which is 17 alpha alkylated, which means it is harder on the liver. Since any damage to the liver is not immediately noticed, and doesn't affect physical appearance, many users opt for Winstrol over testosterone and other injectables.Let's take a look at some Winstrol cycles. First we'll take a look at the basic Winstrol cycle.Approximately ten years ago, the common beginner dosage for Winstrol was roughly 20-25mgs per day. With the internet, and 'more is better', the common dosage today is 50mgs per day. Pharmaceutical Winstrol is often dosed very low, but underground labs generally dose Winstrol for bodybuilders. You will see 10mg, 25mg, and 50mgs capsules of Winstrol.A simple Winstrol cycle would be 50mgs a day, for six weeks. It is suggested to not go past the six weeks to give yoru liver and kidneys a break. The six weeks is a guideline, and many users will take Winstrol for eight, and up to ten weeks. The safest route is if the user can get regular blood work done by the doctor, to make sure everything is healthy.
    A Winstrol cycle with testosterone.

    There are two ways to cycle Winstrol with testosterone, and you'll have an endless argument of which way is better. A bodybuilder can take testosterone for 8-12 weeks, along side with Winstrol, which would be for six weeks. The variation, is you can take the Winstrol starting from day one, up until the end of week six. Or you can take it for the last six weeks of the cycle. When taken at the beginning of the cycle, users will see quicker gains, great pumps in the gyms, usually after only a few days of use... like a 'kick start' to the cycle. The problem with that is, after the first six weeks, the user is only on testosterone for the last 2-6 weeks of the cycle. If the individual starts off with just testosterone, and adds the Winstrol later, they won't see the quicker gangs, however, they will get the benefits of Winstrol closer to the end of the cycle, which in most cases is either around a bodybuilding contest, or middle of summer. In the end, it's a personal choice based on own personal beliefs.
    Week Testosterone
    Weekly
    Winstrol
    Daily
    1 350-500mgs 50mgs
    2 350-500mgs 50mgs
    3 350-500mgs 50mgs
    4 350-500mgs 50mgs
    5 350-500mgs 50mgs
    6 350-500mgs 50mgs
    7 350-500mgs -
    8 350-500mgs -
    Week Testosterone
    Weekly
    Winstrol
    Daily
    1 350-500mgs -
    2 350-500mgs -
    3 350-500mgs 50mgs
    4 350-500mgs 50mgs
    5 350-500mgs 50mgs
    6 350-500mgs 50mgs
    7 350-500mgs 50mgs
    8 350-500mgs 50mgs
    Advanced Winstrol Cycles

    Any advanced cycle usually consists of three or more drugs used in a cycle. There are many options, and most will have testosterone as a base.Testosterone and Winstrol cycle. Though most advanced cycles use three or more compounds, this one only has two, testosterone and Winstrol. The sample cycle is either 12 or 16 weeks. In this cycle Winstrol is taking at the beginning, and the end, with a short break in the middle, to give the body a 'break'.
    Example A
    Week Testosterone
    Weekly
    Winstrol
    Daily
    1 350-500mgs 50mgs
    2 350-500mgs 50mgs
    3 350-500mgs 50mgs
    4 350-500mgs 50mgs
    5 350-500mgs 50mgs
    6 350-500mgs -
    7 350-500mgs -
    8 350-500mgs 50mgs
    9 350-500mgs 50mgs
    10 350-500mgs 50mgs
    11 350-500mgs 50mgs
    12 350-500mgs 50mgs
    Example B
    Week Testosterone
    Weekly
    Winstrol
    Daily
    1 350-500mgs 50mgs
    2 350-500mgs 50mgs
    3 350-500mgs 50mgs
    4 350-500mgs 50mgs
    5 350-500mgs 50mgs
    6 350-500mgs 50mgs
    7 350-500mgs -
    8 350-500mgs -
    9 350-500mgs -
    10 350-500mgs -
    11 350-500mgs 50mgs
    12 350-500mgs 50mgs
    13 350-500mgs 50mgs
    14 350-500mgs 50mgs
    15 350-500mgs 50mgs
    16 350-500mgs 50mgs
    In example A, there is a two week break in the middle, and example B, there is a 4 week break in the middle. Because of the duration of both the cycle and Winstrol use, this cycle may have more side effects.Three Steroid Stack. Once again testosterone is the base. Winstrol is again used at the beginning or the end, but a third steroid is added. The two most common steroids in this situation is Equipoise or trenbolone(Finaplix). Trenbolone is known to have more side effects than Equipoise, so it is also recommended to not take it longer than six weeks. Equipoise is usually taken for the full duration of the cycle.
    Week Testosterone
    Weekly
    Equipoise
    Weekly
    Winstrol
    Daily
    1 350-500mgs 500mgs 50mgs
    2 350-500mgs 500mgs 50mgs
    3 350-500mgs 500mgs 50mgs
    4 350-500mgs 500mgs 50mgs
    5 350-500mgs 500mgs 50mgs
    6 350-500mgs 500mgs 50mgs
    7 350-500mgs 500mgs -
    8 350-500mgs 500mgs -
    9 350-500mgs 500mgs -
    10 350-500mgs 500mgs -
    11 350-500mgs 500mgs -
    12 350-500mgs 500mgs -

    Week Testosterone
    Weekly
    Trenbolone
    EOD*
    Winstrol
    Daily
    1 350-500mgs 100mgs 50mgs
    2 350-500mgs 100mgs 50mgs
    3 350-500mgs 100mgs 50mgs
    4 350-500mgs 100mgs 50mgs
    5 350-500mgs 100mgs 50mgs
    6 350-500mgs 100mgs 50mgs
    7 350-500mgs - -
    8 350-500mgs - -
    *EOD - Every Other DayThat covers three variations of Winstrol cycle. A Winstrol only cycle, and intermediate cycle, and advanced cycles. Included with these steroids can also be a clenbuterol cycle.

    Stanozolol ? Winstrol (Oral) & Winstrol Depot (Injectable)

    Stanozolol is a synthetic derived from testosterone. Technically classified as an anabolic steroid, Stanozolol is commonly sold under the brand name winstrol. Created by the Winthrop Laboratories in 1962, winstrol is one of the most popular anabolic steroids. Winstrol is a registered trademark of Sanofi-Synthelabo Inc. in the United States and/or other countries. Sanofi has licensed rights of Wnstrol to Ovation Pharmaceuticals. Winstrol is commonly marketed as Winstrol (oral) and Winstrol Depot (injectable).



    USAGE ? The United States FDA (Food and Drug Administration) has approved winstrol for human use. Medically, winstrol is used in both animals and human patients to treat a number of conditions. Winstrol is commonly used for the treatment of anaemia and hereditary angioedema that causes episodes of swelling of the face, extremities, genitals, bowel wall, and throat in humans.

    Winstrol has substantial fibrinolytic properties. It has been effective treatment for urticaria, Raynaud's phenomenon, cryptofibrinogenemia, and lipodermatosclerosis. It has also been used to cure osteonecrosis in cases; it is resistant to all other therapy. The drug also has been successfully used in treatment of AIDS wasting syndrome. Winstrol is often used to improve muscle growth, red blood cell production, increase bone density and stimulate the appetite in weak and feeble animals. Winstrol is widely used by muscle builders for its anabolic and androgenic effects. Average Dose for men is 50-100 mg/day, and for women is 25-50 mg/week.

    CHEMISTRY ? winstrol is a DHT (dihydrotestosterone) derivative. It is a 17AA steroid. It is chemically designated as 17-methyl-2' H -5(alpha)-androst-2-eno[3,2- c ]pyrazol-17(beta)-ol. In winstrol (oral), Stanozolol is solidified into tablet form, and each tablet contains 2 mg of stanozolol. Stanozolol is aqueous in winstrol Depot. Inactive Ingredients of winstrol include Dibasic Calcium Phosphate, D&C Red #28, FD&C Red #40, Lactose, Magnesium Stearate, and Starch. Active Life of winsrol is around 48 hours.

    SIDE EFFECTS ? overuse or high doses of winstrol are often linked with cause serious side effects. Some of the side effects of winstrol are ? allergic reactions, such as difficulty in breathing, choking of the throat, swelling of the lips, tongue, or face, or hives; swelling of the arms or legs, especially ankles; frequent or persistent erections, breast tenderness, breast enlargement (males), voice changes (hoarseness, deepening), hair loss, facial hair growth, clitoral enlargement (females), menstrual irregularities (female), worsening acne, difficulty in sleeping, headaches, and changes in sexual desire.

    LEGAL STATUS ? winstrol has been classified as a Schedule III controlled substance under federal regulation. It has been banned from use in sports competition by the International Association of Athletics Federations (IAAF).


    Last edited by Presser; 09-23-2019 at 08:42 AM.
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    Winstrol Cycle - Winsrol Stanozolol Cycle with Testosterone

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    Quote Originally Posted by Presser View Post
    Testosterone Propionate, trenbolone acetate and Winstrol Cycle - Stanozolol Cycle




    Week Testosterone
    Propionate
    EOD
    Trenbolone
    EOD*
    Winstrol
    Daily
    1 200mgs 100mgs 50mgs
    2 200mgs 100mgs 50mgs
    3 200mgs 100mgs 50mgs
    4 200mgs 100mgs 50mgs
    5 200mgs 100mgs 50mgs
    6 200mgs 50mgs
    7 200mgs - -
    8-12


    200mgs
    -100mgs -50mgs
    *EOD - Every Other DayThat covers three variations of Winstrol cycle. A Winstrol only cycle, and intermediate cycle, and advanced cycles. Included with these steroids can also be a clenbuterol cycle.
    I changed this cycle and edited it more to my liking above, and for the record I run Insulin-like-growth factor-1 lr3 throughout the entire cycle at 50mcgs on average. Great cycle for bulking and cutting, and if pre contest i would drop the propionate at about 10 days out and drop winny at same time, and run the tren ace straight through the show, as for the igf-1 lr3, i also cut that at 14 days out, though a lot of guys will run their igf and tren together straight through the show.

    I quite literally have given myself an injection on the day of a show with tren ace, worked like a charm!
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    Winstrol Cycle - Winsrol Stanozolol Cycle with Testosterone

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    Great thread Presser
     

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    thnx man, love my winstrol
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    Some basic stanozolol information. How to cycle winstrol, do I take wonstrol every day or can I take winny every other day. Is it best to split up my winstrol dosages throughout the day or can I take my winstrol all at once. Can I drink Injectable winstrol..answer YES its a 17aa steroid.

    Is injectable winstrol better than oral winny tabs, i say NO.

    Does winstrol (stanozolol) really make your joints hurt....answer....YES

    what stacks best with winstrol. answers , Testosterone propionate, tren ace and Lr3 IGF-1

    Any other questions feel free to ask!
    Winstrol Cycle - Winsrol Stanozolol Cycle with Testosterone

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    Will an over the counter estrogen blocker be sufficient with this stack or is one even necessary?
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    no you will need real pct meds
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    Thank you for all the good info presser, would nolvadex for pct be fine with just running test e for 10 wks and winny the last 6?
    thankyou
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    Quote Originally Posted by Fmira View Post
    Thank you for all the good info presser, would nolvadex for pct be fine with just running test e for 10 wks and winny the last 6?
    thankyou
    it will be good for estrogen rebound, but clomid would be best started 2-3 weeks after your last shot of testosterone enanthate.
    Winstrol Cycle - Winsrol Stanozolol Cycle with Testosterone

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    For our winstrol Loving folk, myself included as i think winstrol is amazing when taken with the right combination of steroids. like:

    Propionate, and IGF-1 Lr3, and some times Tren, lol, some times! lol

    Bump stanozolol
    Winstrol Cycle - Winsrol Stanozolol Cycle with Testosterone

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    Question: did/would you run a/I with this such as aromasin?

    Also can you provide pct for the basic schedule with winny on the back again.
    Much appreciated. Good post.
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    Good read
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    Quote Originally Posted by Mark.stevens112 View Post
    Question: did/would you run a/I with this such as aromasin?

    Also can you provide pct for the basic schedule with winny on the back again.
    Much appreciated. Good post.
    for the propionate, tren ace, winstrol and igf-1 lr3 cycle i would be sure my pct included arimidex, nolvadex, clomid and hcg throughout the cycle with dostinex throughout the cycle to help combat the trenbolone aromitization
    Winstrol Cycle - Winsrol Stanozolol Cycle with Testosterone

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    Presser question for you...what did tren ace do for you the day of the show?......I run igf all the way through til the day of and the really hit every body part with 50 mug half hour before pump up and pre judging......seems to make me fuller and muscle pop.......so about 400 mcgtotal morning of show....so wondering what tren ace can do as well if done the day of....thanks

    E
     

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    Quote Originally Posted by eswol View Post
    Presser question for you...what did tren ace do for you the day of the show?......I run igf all the way through til the day of and the really hit every body part with 50 mug half hour before pump up and pre judging......seems to make me fuller and muscle pop.......so about 400 mcgtotal morning of show....so wondering what tren ace can do as well if done the day of....thanks

    E
    Well considering i stopped all other gear 10-14 days out like my prop was 10 days out, and igf was around that time out to, so the trenbolone acetate was to help make sure i was able to still pump up back stage and it also helped make sure i did not retain any subcutaneous water the day of the show and was hard as a rock.

    Now I got this from an old member here who was a National Level Competitor if anyone remembers him , he went by "dpsquat" anyhow, he helped prep me here at MuscleChemistry for my first couple shows ever, and thats where I got running trenbolone acetate through the show on day of show, and also where i got the "eat a flank steak for breakfast the morning of the show" and I won my firsts hows overall and placed 1st in my class in every show since, and never strayed from my precontest prep.

    Anyhow, below is not a great photo of dpsquat, his onstage pictures were impressive though! He use to be a rep here and also worked for Schwartzlabs supplements which we use to sell here 14 years ago or so lol

    I cant find his stage pics, which are phenominal

















    Winstrol Cycle - Winsrol Stanozolol Cycle with Testosterone

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    What is PCT for test and winstrol?
    Can you use testim testosteron(gel) on this cycle?
    If you have 10mg tabs of winstrol and you have to take 50mg daly do you take 5 tabs togehter or do you take it in separate time?

    Thank you for answer!
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    Quote Originally Posted by Proteincek View Post
    What is PCT for test and winstrol?
    Can you use testim testosteron(gel) on this cycle?
    If you have 10mg tabs of winstrol and you have to take 50mg daly do you take 5 tabs togehter or do you take it in separate time?

    Thank you for answer!
    split the tabs up into 2 or 3 times daily, I would just take split it in half daily, and post cycle therapy for Testosterone and winstrol all depends on how long your using them, and at what dosage, and we need to know what ester testosterone your using in order to determine the PCT start time. As Propionate would be much sooner pct start than say cypionate or enanthate.

    So everything is relative daddio
    Winstrol Cycle - Winsrol Stanozolol Cycle with Testosterone

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    I was looking for this cylce 8weeks test 350mg weekly and winstrol 50mg daly.
    I would use testim testosteron(gel) wich has basic testosteron and one "gel" has 50mg of basic testosteron inside so I will have to take this every day + 10mg tabs of winstrol.
    So what would you recommend for PCT?
     

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    I didnt even know testosterone gels were being used, not even last year!

    I thought a Big lawsuit for dosing inaccuracies in the gel had kinda killed off this B.S. transdermal testosterone .

    Even had a couple lawyers who wanted to advertise their class action suit here to get more people on board. Crazy!
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    My next cycle i'm thinking of running 100mg for 50 days. Haven't planned my cycle yet but I also have dbol and anavar thinking a 20 weeker.
     

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    Presser those are some solid cycles!
    What liversupport do you recommend/take?

    Do you think that 12 weeks is enough taking EQ? Many people recommend 14-16w and higher dosages, RBC gets too high though.
    How do can you run orals for that long at that dosage?
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    Quote Originally Posted by thx View Post
    Presser those are some solid cycles!
    What liversupport do you recommend/take?

    Do you think that 12 weeks is enough taking EQ? Many people recommend 14-16w and higher dosages, RBC gets too high though.
    How do can you run orals for that long at that dosage?
    Boldenone (equipoise) in my humble opinion needs to be run 16 weeks unless you were to frontload it as to get to whatever hormone level your shooting for as soon as possible. I personally didnt know shit about frontloading properly with injectables in my younger years, so have no real world experience doing it properly, but i have frontloaded equipoise for this reason the last time i ran EQ, and I got super sick, I believe from frontloading it , and had to stop everything.

    In any case, to be specific to your question, yes i think 16 weeks minimum if your going to use it the traditional way, which is weekly injections, and it takes a while to build up as you know. However i would love to hear some EQ Frontload success stories and ask how fast they were able to get to peak levels and how long they stayed on the EQ, as i think maybe 10 to 12 weeks is possible provided your able to get the boldenone hormone levels peaked and level sooner than you would with traditional methods as i touched on above.


    As for long cycle runs with Stanozolol (winstrol, 17aa- injectable or oral) and how to protect and support a healthy liver I will list some solid choices below this post:
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    Default Liver Support Agents S-adenosylmethionine and N-acetylcysteine (NAC) Especially Important During Oral / Injectable Steroid Cycles

    (S-adenosylmethionine) is serious medicine against liver disease. Almost a thousand published studies document the ability of this bioactive form of methionine to prevent and treat liver disorders, including cancer.

    SAMe, the amazing "super-nutrient," can single-handedly normalize liver function. How? SAMe is the central player in liver biochemistry. It does two crucial things: It methylates, and it transforms itself into the liver's most vital substance, glutathione.

    The liver contains the third highest amount of SAMe in the body, after the adrenal and pineal glands. SAMe is so important for liver function that it can be considered an essential nutrient for that organ. In addition to its many other functions, SAMe plays a leading role in liver regeneration. The liver has special SAMe enzymes just for regenerating tissue.

    The liver has a tough job. It has to break down every chemical the body encounters, including drugs. It has to filter blood, chase after bacteria, make bile, and create various other substances such as lipoproteins. In short, there is a reason the liver is the only organ that readily regenerates: It has to.

    SAMe is the product of a biochemical reaction between ATP and methionine. Half of all methionine in the body is used in the liver to make SAMe. SAMe has been compared to ATP in its importance for the body. It is used in many different cellular processes, from replication to biochemical reactions that create melatonin and phosphatidylcholine. SAMe is particularly important for the liver because glutathione is synthesized from it. Glutathione is crucial for liver function. A good portion of liver SAMe is turned into glutathione. Glutathione is the liver's natural antioxidant.

    SAMe has been isolated from yeast and purified. It is currently sold in Europe as an antidepressant. Many clinical studies have been conducted with this supplemental form of SAMe. It has been used in trials against depression, osteoarthritis and other conditions. Of all the published studies, the ones on the liver are perhaps the most comprehensive.

    The Liver Super-Nutrient

    SAMe is the liver super-nutrient. Nothing comes close to providing the spectrum of health benefits that SAMe provides for the liver. Based on published clinical trials, elevating SAMe levels can have a powerful effect on many conditions. As a preventive agent, SAMe is so powerful that it can reverse the effects of chemicals and alcohol as they occur. Studies show that low SAMe levels create the conditions for liver cancer, and that SAMe can prevent these conditions from occurring. Anyone concerned about the effects of drugs, chemicals, alcohol and aging on their livers should look into the benefits of SAMe.
    dosage required : 400mgs /day


    SAM-e Promotes Liver Health
    The liver is unique because it is the only internal human organ capable of regenerating itself. As little as 25% of a liver can regenerate into a whole liver again, and SAM-e plays a leading role in that regeneration. The third highest amount of SAM-e in the body is found in the liver. Only the adrenal and pineal glands contain more.
    SAM-e is thought to be beneficial for those with liver disease by acting as a precursor of antioxidant glutathione; repairing the mitochondrial glutathione transport system; inhibiting the toxic effects of proinflammatory cytokines; and increasing DNA methylation.(7)
    There are nearly a thousand published studies documenting SAM-e's ability to support prevention and improvement in liver disease.
    • In a study of hepatic glutathione levels in patients with liver disease, participants were divided into four groups. Nine patients with alcoholic liver disease were given SAM-e; seven patients with non-alcoholic liver disease were given SAM-e; 8 patients with alcoholic liver disease were given a placebo; and 15 normal subjects served as a control group. Prior to beginning treatment, all patients had very low hepatic glutathione levels compared to controls. Following treatment, patients receiving the SAM-e had a significant increase in their hepatic glutathione levels compared with both the placebo-treated group and controls.(8)
    • When SAM-e was given to 62 patients with alcoholic cirrhosis in a clinical trial, they were significantly less likely to die or require a liver transplant within the next two years, compared with 61 patients who had received a placebo.(9)

    SAM-e Is Promising for Fibromyalgia Patients
    Although SAM-e has not been studied yet as much for support of fibromyalgia patients as for those with some other illnesses, the results thus far are encouraging. In one double-blind study of 44 patients with primary fibromyalgia, improvements were seen in the areas of clinical disease activity, pain, fatigue, morning stiffness and mood.(10)
    SAM-e's Role in Alzheimer's Disease
    Since extremely low levels of SAM-e were found in the cerebrodpinal fluid and brain regions of Alzheimer's patients in a 1996 study, researchers are examining the potential benefits of supplemental SAM-e in Alzheimer's.(11) A recent study stated, “...our findings suggest that dietary supplementation with SAM... holds promise as a therapeutic approach to prevent or delay AD. A preliminary study indicates that SAM can provide some cognitive improvement in AD patients.”(12)
    Facts About SAM-e You Need to Know
    Dosage: Recommended therapeutic doses usually range between 400 – 1600 mg a day, although some individuals may require higher doses. Studies suggest that 400 mg per day may be adequate for osteoarthritis patients, while up to 1600 mg a day is often needed for mood support. The usual dose for those with liver disorders has been 1600 mg a day. (As with any addition to your health support regimen, supplementation with SAM-e should be considered only with the approval of your professional healthcare team.)
    How to Take SAM-e: SAM-e works best when taken on an empty stomach. Because it is absorbed mainly in the intestine, enteric-coated tablets that allow it to pass through the stomach intact are preferable. Leave tablets in their foil or foil blister packs until you are ready to take them in order to maintain their stability.
    Adverse Effects: There seem to be few adverse effects with SAM-e, even at high doses. Occasionally mild gastrointestinal distress has been reported. Since SAM-e can sometimes lead to insomnia, it is usually best to take it early in the morning. Because it plays a role in mood support, SAM-e may trigger manic episodes in people with bipolar disorder.
    Contraindications: While there are no confirmed drug interactions with SAM-e, individuals using prescribed medications such as antidepressants, including serotonin re-uptake Inhibitors and MAO inhibitors, should consult a physician before using. Individuals with Parkinson's disease, bipolar disorder or manic depression should not take SAM-e.
    In Summary
    More than three decades of solid research support the use of SAM-e to help promote natural improvement in symptoms of osteoarthritis, depression and liver disease. Ongoing research is also revealing its promising potential for those with a number of other conditions.
    ______
    References:
    1. Williams AL, et al. “S-adenosylmethionine (SAMe) as treatment for depression: a systematic review.” Clin Invest Med. 2005 Jun;28(3):132-9.
    2. Rosenbaum JF, et al. “The antidepressant potential of oral S-adenosyl-l-methionine.” Acta Psychiatr Scand. 1990 May;81(5):432-6.
    3. Bell KM, et al. “S-adenosylmethionine blood levels in major depression: changes with drug treatment.” Acta Neurol Scand Suppl. 1994;154:15-8.
    4. Soeken KL, et al. “Safety and efficacy of S-adenosylmethionine (SAMe) for osteoarthritis.” J Fam Pract. 2002 May;51(5):425-30.
    5. Wadie IN, et al. “S-Adenosyl methionine (SAMe) versus celecoxib for the treatment of osteoarthritis symptoms: A double-blind cross-over trial.” BMC Musculoskelet Disord. 2004;5:6.
    6. Konig H, et al. [Magnetic resonance tomography of finger polyarthritis: morphology and cartilage signals after ademetionine therapy] Aktuelle Radiol. 1995 Jan;5(1):36-40.
    7. Purohit V, Russo D. “Role of S-adenosyl-L-methionine in the treatment of alcoholic liver disease: Introduction and summary of the symposium.” Alcohol. 2002 Jul;27(3):151-4.
    8. Vendemiale G, et al. “Effects of oral S-adenosyl-L-methionine on hepatic glutathione in patients with liver disease.” Scand J Gastroenterol. 1989 May;24(4):407-15.
    9. Mato JM, et al. “S-adenosylmethionine in alcoholic liver cirrhosis: a randomized, placebo-controlled, double-blind, multicenter clinical trial.” J Hepatol. 1999 Jun;30(6):1081-9.
    10. Jacobsen S, et al. “Oral S-adenosylmethionine in primary fibromyalgia. Double-blind clinical evaluation.” Scand J Rheumatol. 1991;20(4):294-302.
    11. Morrison LD, et al. “Brain S-adenosylmethionine levels are severely decreased in Alzheimer's disease.” J Neurochem. 1996 Sep;67(3):1328-31.
    12. Tchantchou F, et al. “S-adenosyl methionine: A connection between nutritional and genetic risk factors for neurodegeneration in Alzheimer's disease.” J Nutr Health Aging. 2006 Nov-Dec;10(6):541-4.
    __
    * Karen Lee Richards is Lead Expert specializing in Fibromyalgia and ME/CFS, for HealthCentral's ChronicPainConnection (www.chronicpainconnection.com). Karen is co-founder of the National Fibromyalgia Association (NFA) and was Executive Editor of Fibromyalgia AWARE magazine for four years.
    Note: This information has not been reviewed by the FDA. It is general and is not meant to diagnose, prevent, treat or cure any condition, illness, or disease. It is very important that you make no change in your healthcare plan or health support regimen without researching and discussing it in collaboration with your professional healthcare team







    2) NAC- everybody knows this one,N-acetylcysteine (NAC), which is used as a mucolytic agent in COPD and other diseases, was also found to be a powerful antioxidant, as a precursor of reduced glutathione, and a potential therapeutic agent in the treatment of diseases characterized by free radical and oxidant damage and a must have for sure,look at this study;

    Patients who have had a recent heart attack, ulcerative colitis, or adult respiratory distress syndrome may be deficient in glutathione (GSH), an important protector of liver cells, red blood cells, and lymphocytes.

    Lower glutathione levels in plasma and lung fluid have also been seen in patients with human immunodeficiency virus (HIV) infection. It is thought that low glutathione levels speed up the development of emphysema in HIV-positive patients, especially if they have a history of smoking. Patients who are co-infected with HIV and hepatitis C (HCV) have even further diminished levels of glutathione.
    A new study by De Rosa and colleagues, published in the European Journal of Clinical Investigation, investigated the use of N-acetylcysteine (NAC), a mucolytic agent used to reduce the viscosity of mucus and to build up glutathione levels in HIV-positive patients. In an 8-week test, 31 patients received NAC and 30 received a placebo. Both groups began the study with low glutathione levels.

    Results showed that the patients who received NAC had near-normal glutathione levels, whereas levels in the placebo group remained the same. No side effects were reported, although occasional dose reduction was necessary to diminish gastrointestinal effects.

    Anti-HIV protease inhibitors are known to be toxic to the liver, especially in patients with both HIV and hepatitis, and the NAC results are therefore significant. In a study of 24 patients, interferon and NAC treatment reduced liver abnormalities better than interferon alone.

    dosage required: 2000 mg ed

    3) liv 52
    dosage required: 9 tabs/day

    4)milk thistle, sylmarin
    dosage required: 1800 mg ed

    everybody knows this 2 but if you have doubts check this link you got millions of studies to prove their efficacy:

    LiverSupport.com

    one note on the milk thistle , some say it inder gains, where`s why:

    Milk Thistle: Good for Livers, Potentially Bad for Gains

    Title: Silymarin inhibits function of the androgen receptor by reducing nuclearlocalization of the receptor in the human prostate cancer cell line LNCaP.Authors: Zhu W, Zhang JS, Young CY.Source: Carcinogenesis 2001 Sep;22(9):1399-403
    Research Summary
    Agents with novel mechanisms of blocking androgen receptor (AR) function may be useful for prostate cancer prevention and therapy. Previous studies showed that silibinin (SB), the major active component of Milk Thistle, could inhibit cell proliferation of a human prostate cancer cell line by stopping the cell cycle without causing cell death. This study further demonstrates the potential molecular mechanism by which Milk Thistle acts on androgen-responsive prostate cancer cells by inhibiting function of the AR. We observed that Silymarin (SM) and SB inhibited androgen-stimulated cell proliferation as well as androgen-stimulated secretion of both prostate-specific antigen (PSA) and human glandular kallikrein (hK2).Additionally, for the first time, we show that SM and SB diminished transactivation activity of the AR. However, SM did not affect AR levels and steroid-binding ability of total AR in western blotting and ligand-binding assays. Intriguingly, we found that nuclear AR levels are significantly reduced by SM and SB in the presence of androgens. This study provides a new insight into how Milk Thistle negatively modulates androgen action in prostate cancer cells.

    Discussion

    Milk Thistle is a popular bodybuilding supplement and is currently the most well researched plant for the treatment of liver disease (with over 450 published peer review papers). Silymarin, a flavonoid extract from Milk Thistle, has been used clinically for alcoholic liver disease treatment in Europe and Asia for almost 2,000 years. Currently it?s used by bodybuilders as a protective measure for the liver when using high doses of orals.Silymarin is not water soluble and is typically administered as an encapsulated standardized extract. The absorption with oral administration is rather low, with only two to three percent being effectively taken up. The peak plasma levels after an oral dose are achieved in four to six hours. The reason this study is significant is because of the described mechanism that Milk Thistle is working in the prostate. It is showing effectiveness in treating prostate cancer because it prevents the androgen receptor from making it to the nucleus of the cell. This may be good if you are fighting cancer of the prostate, but it is bad if you are trying to get a muscle cell to grow larger.In order for testosterone to work, it must pass from the blood to the inside of a muscle cell, bind to the androgen receptor inside the cell, then travel inside the nucleus where it binds to your DNA.These researchers were able to show that Milk Thistle did not reduce the number of androgen receptors, nor did it prevent androgens (i.e., testosterone) from binding to the receptors. All it seemed to do was prevent the androgen receptor from traveling to the nucleus, and in our case, this prevents the desired effect. The androgen receptor, once bound to the androgen, must make it to the nucleus in order to increase protein synthesis.Bottom line: Use Milk Thistle if you are sure you are having liver toxicity problems. Then, only use it for a few weeks at a time. There are other herbs with tremendous hepatoprotective effects, so you might give them a try instead.


    As seen controversial to say the least, do your choice...

    5) Tauroursodeoxycholic acid (TUDCA) - this is a relatively recent new liver aid , introduced in the market as a supplement by thermolife(LIVER LONGER) it looks like a very good help in preventing cholestasis, one of the major risk with 17 alkylated steroids:

    TUDCA prevents cholestasis and canalicular damage induced by ischemia-reperfusion injury in the rat, modulating PKCα–ezrin pathway

    Cholestasis, induced by liver ischemia-reperfusion injury (IRI), is characterized by dilatation of bile canaliculi and loss of microvilli. Tauroursodeoxycholic acid (TUDCA) is an anti-cholestatic agent, modulating protein kinase C (PKC) α pathway. PKC reduces ischemic damage in several organs, its isoform α modulates ezrin, a key protein in the maintenance of cell lamellipoidal extensions. We evaluated the effects of TUDCA on cholestasis, canalicular changes and PKCα–ezrin expression in a rat model of liver IRI. Livers flushed and stored with Belzer solution or Belzer + 10 mm TUDCA (4 °C for 6 h) were reperfused (37 °C with O2) with Krebs–Ringer bicarbonate + 2.5 μmol/min of Taurocholate or TUDCA. Bile was harvested for bile flow assessment. Liver tissue was employed for Electron Microscopy (EM) and for PKCα and ezrin immunoblot and immunofluorescence. The same experiments were conducted with the PKCα inhibitor Go-6976. TUDCA-treated livers showed increased bile flow (0.25 ± 0.17 vs. 0.042 ± 0.02 μl/min/g liver, P < 0.05) and better preservation of microvilli and bile canalicular area at EM. These effects were associated with increased PKCα and ezrin expression (P = 0.03 and P = 0.04 vs. control respectively), as also confirmed by immunofluorescence data. PKCα inhibition abolished these TUDCA effects. TUDCA administration during IRI reduces cholestasis and canalicular damage in the liver modulating PKCα–ezrin pathway.


    https://www.blackwell-synergy.com/doi...ournalCode=tri

    dosage required: 2 X 250 mg ed with meals

    6) Essential forte N - this is a otc(at least in europe) Multivitamins and phospholipids complex that really helps keeping the liver in shape when a steroid cycle its done, if money its not a problem put it on your arsenal:

    Abstract
    Introduction. Androgenic-anabolic-steroids (AAS)-induced hepatotoxicity typically occurs with C-17 alkylated oral agents abused by exercising individuals at clinically recommended doses. Injectable compounds appear to have the same risk for hepatotoxicity, but are applied in doses three to six times higher than clinically recommended. AAS users occasionally try to avoid the well-known hepatotoxic effects associated with the abuse of a multitude of AAS agents, by using the pharmaceutical agent compound N a phospholipid/vitamin preparation. Primary Objective. The investigation of the actual hepatoprotective effect of compound N against AAS-induced toxicity. Methodology. This was an observational cohort study of 320 athletes; 160 were AAS users and the other 160 were not abusing any substances. Of the 160 users, 44 were using AAS and compound N (group A), and 116 were using solely AAS (group B). The 160 athletes abstaining from substances abuse acted as controls (group C). All athletes were tested for alterations in serum levels of hepatic enzymes. Enzyme levels before the study's onset and after the end of the 8-week AAS regimes were compared among the three groups, in order to delineate the hepatoprotective effect of compound N. Results. Prior to our research all groups showed normal values in all enzymes except creatine kinase (CK). After the 8-week period, CK levels were slightly lower in group A, but without variation in Groups B and C; γ-Glutamyl Transferase (γGT) levels remained normal. Groups A and C had no elevations in any of the enzymes, except CK, while in group B all enzymes' values were elevated above the normal range. The only factor differentiating AAS users in group A from those in group B was the use of compound N, thus the results being suggestive of the compound's detoxification effect. The severity of AAS abuse was positively associated with the degree of changes (Δ values) in all measured enzymes except γGT and CK. Conclusions. Previous suggestions that serum hepatic enzyme elevations in exercising AAS abusers are connected to muscle fiber damage rather than the abuse itself, are contradicted by our results. Since all AAS abusing athletes were prone to exhibit elevations in enzymes' values, the mean values of group A were to be similar to those observed in group B, exceeding normal values. The group hepatic enzyme values of group B were significantly higher than the group C (control). Notably, group A did not have any statistically significant difference in the hepatic enzyme values compared to group C. The effect of exercise on these enzymes' elevations was ruled out by the comparability of training regimens and AAS toxicity was correlated to the severity of AAS abuse.

    Multivitamins and phospholipids complex protects t...[Clin Toxicol (Phila). 2008] - PubMed Result

    dosage required: at least 2 caps 3 times day with meals

    7) Sesamin- Cheap and as the following study show a liver protector:

    Protective effects of sesamin against liver damage caused by alcohol or carbon tetrachloride in rodents.

    The effects of sesamin, a potent inhibitor of delta 5-desaturase in polyunsaturated fatty acid biosynthesis, on the fatty acid compositions of tissue lipids and liver functions were examined in rodents. When a mixture of sesamin and episesamin (51.1:48.2, w/w) was given to rats at a dietary level of 0.5% for 13 days, the proportions of dihomo-gamma-linolenic acid significantly increased not only in the liver but also in plasma and hemocytes, suggesting an interference with delta 5-desaturation by these lignans. The sesamin preparation at the dietary level of 1% improved changes in various blood parameters of the mouse, such as aspartate aminotransferase and alanine aminotransferase activities, and the concentrations of total cholesterol, triglyceride and total bilirubin, caused by continuous inhalation of ethanol. In addition, sesamin showed a significant protective effect against the accumulation of fat droplets and vacuolar degeneration in the mouse liver, as confirmed on histological examination. Sesamin, at the level of 100 mg/kg body weight, also tended to prevent liver lipid accumulation by carbon tetrachloride in mice. These results indicate that sesamin and a related lignan compound have an ability to improve liver function.
    Protective effects of sesamin against liver damage...[Ann Nutr Metab. 1993] - PubMed Result
    dosage requeired :2000 mg ed
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    Winstrol Cycle - Winsrol Stanozolol Cycle with Testosterone

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    Floating back to the top. Solid liver health information at the end of the winstrol article
    Winstrol Cycle - Winsrol Stanozolol Cycle with Testosterone

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    Default Optimizing Cutting Cycles: Advanced Strategies with Winstrol and Testosterone

    Optimizing Cutting Cycles: Advanced Strategies with Winstrol and Testosterone


    Enhancing Your Winstrol Cycle: The Role of Testosterone
    Incorporating Testosterone into your Winstrol cycle can significantly enhance muscle retention and strength. Testosterone, often considered the foundation of most steroid cycles, complements Winstrol's cutting effects by preserving muscle mass and improving overall body composition.


    Strategic Dosing for Maximum Efficiency
    To optimize the benefits of Winstrol and Testosterone, strategic dosing is essential. For beginners, lower dosages are advisable to gauge the body's reaction, while experienced users might opt for higher doses within safe limits. Regular blood tests are recommended to monitor the body’s response and adjust dosages accordingly.


    Timing Your Cycle for Peak Results
    Timing is crucial in a Winstrol and Testosterone cycle. Starting with Testosterone and introducing Winstrol mid-cycle can help maintain muscle hardness and definition. Alternatively, beginning with Winstrol can offer a 'kickstart' for rapid gains, followed by the sustaining effects of Testosterone.


    Winstrol Only vs. Stacked Cycles
    While a Winstrol-only cycle is common for cutting, stacking with Testosterone can offer enhanced benefits. This combination provides a balance between muscle definition and strength, making it a preferred choice for many bodybuilders.


    Managing Side Effects for a Safe Cycle
    Understanding and managing potential side effects is crucial. Winstrol's hepatotoxicity and Testosterone's estrogenic effects, such as water retention and gynecomastia, require attention. Using liver protectants and aromatase inhibitors can mitigate these risks.


    Advanced Cycle Options: Incorporating Other Steroids
    For more experienced users, adding a third steroid like Trenbolone or Equipoise can further enhance the cycle's effectiveness. These combinations can offer more pronounced muscle definition and strength gains.


    The Importance of Post-Cycle Therapy (PCT)
    Post-Cycle Therapy is essential in restoring the body’s natural hormone production. A well-planned PCT, typically involving Clomid or Nolvadex, is crucial following a Winstrol and Testosterone cycle.


    Conclusion
    A Winstrol and Testosterone cycle, when planned and executed correctly, can be a powerful tool in achieving cutting goals. By understanding the nuances of dosing, timing, and side effect management, bodybuilders can maximize their results while maintaining safety.

    Winstrol Cycle - Winsrol Stanozolol Cycle with Testosterone

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