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Thread: DNP - Uncoupling to burn fat
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01-22-2018, 09:26 AM #1
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DNP - Uncoupling to burn fat
New and exciting research in the never-ending battle on obesity. This study has identified a new enzyme, PM20D1, that is enriched in UCP-1(uncoupling protein1). UCP-1 is a protein responsible for generating heat(thermogenesis) which decreases the proton gradient(energy)needed to make ATP. The really cool part is that PM20D1 makes N-acyl amino acids(amino acids combined with a fatty acid), which can activate UCP-1, therefore acting as a new source of fat burning via uncoupling. Uncoupling basically means your body is losing energy that normally makes ATP and the response is breaking down fat to generate the energy needed to keep producing ATP(so you don't die).
DNP is the poster child for uncoupling and is known for burning up to a pound a day of pure fat, but it's very toxic. These N-acyl amino acids also have been shown in mice to improve glucose metabolism and increase total energy expenditure. More human data is needed, but essentially it's possible that supplementing with N-acyl aminos might be novel way to burn fat safely via uncoupling, as they are endogenously produced. For more info on uncouplingPresser, yellow snow liked this post
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01-22-2018, 10:29 AM #2
That would be nice! I know a lot of guys and girls here love their DNP but personally im not a fan of ingesting pesticides to lose weight, lol, call me old fashion but I keep all my supplements above the sink not under it!! Yeah that was a pretty good “sink” thing, what can I tell you, im smart like that lmao
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01-22-2018, 10:33 AM #3
why can’t I like and thank my own posts, lol
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01-22-2018, 11:50 AM #4
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04-18-2018, 09:34 AM #5
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Nothing burns fat like drano!!!
yellow snow liked this post
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04-18-2018, 10:23 AM #6
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04-18-2018, 07:07 PM #7drtbear1967 thanked for this post
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06-29-2018, 03:26 PM #8
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