The Iron Bull
Banana
I am writing this but cannot take credit for it all. This line of reasoning was pointed out to me by a bro who wishes to now remain anonymous.
The goal of injecting steroids is to increase blood levels of testosterone much higher than can be achieved normally. One of our criteria in doing this is to keep blood levels as stable as possible throughout cycle to provide the best environment for growth and to avoid as many sides as possible. I believe many side effects are caused by the spikes and dips created by once or twice a week injections, even using long esters. A way to reduce these sides would be to use a proper half life to determine when to inject or more importantly how much to frontload with.
Now most half lives are calculated on 1.5 x the number of carbon atoms to determine 1/2 life in days. That’s wrong! If you go to PubMed or AMJ you can look up numerous studies showing a much shorter half life(@ .7 per carbon atom)
That difference is because esters decay at a logarithmic rate, meaning the more esterified hormone in the injection depot, the more is released. This release rate slows as the amount of esterified hormone in the depot is reduced over time.
The general rule is about 0.7 X the number of carbons atoms in a linear ester . However when the body builder needs to keep in mind is that the majority of the esterified hormone is released, regardless of the ester, with the first 24hrs of injection because of the logarithmic rate of decay.
What does this mean in simple terms?
I'll use Testosterone Enanthate in an 8 week cycle as an example:
Assume a 5 day half life for Enanthate based on .7 x it's carbons.
Injecting 579mg on day one of your cycle will provide stable levels of 550 mg per week for the duration of your cycle provided you replenish 75 mg EVERY DAY.
INJECT
Day 1- 579- giving you 550 mg in 24 hours
Day 2 75 giving you 550 mg
Day 3 75 550
Day 4 75 550
Day 5 75 550
Day 6 75 550
Day 7 75 550
Day 8 75 550
Day 9 75 550
Day10 75 550
Day11 75 550
Day12 75 550
and so on until day 57 when you stop injections
decay clearance is as follows
DAY Total MG
58 479
59 417
60 363
61 316
62 275
63 240
64 209
65 182
66 158
67 138
68 120
69 104
70 91
71 79
72 69
73 60
74 52
75 45
76 40
77 34
78 30
79 26
80 23
81 20
82 17
83 15
84 13
85 11
all the way down to day 98 (end of week 14) before the Enanthate is totally cleared
--------------------------------------------------------------------------------
Enanthate Clearance 500 mg
Now let's look at 1 shot of Test Enanthate of 500mg taken on day one.
It will take 8 weeks to clear (assuming a 5 day 1/2 life)
DAY Injected 500 mg(level)
1 500
2 475
3 414
4 360
5 313
6 273
7 238
8 207
9 180
10 157
11 136
12 119
13 103
14 90
and so- on until week 9 when it reaches 0.
--------------------------------------------------------------------------------
Enanthate injected E3D at 250 mg-levels
Now lets look at Injections of Test Enanthate every 4 days with 250 mg.
Blood levels are all over the place and create many dips and spikes.
Not a prime anabolic environment. It takes 7 days and 3 injections to even get to 500 mg(498) and then continues to dip and spike the 500 mark until week 4 but then the spikes are over 600 mg. This daily fluctuation cannot be good for combating sides or keeping steady growth rate.
The other way to look at it is $$$$. 500 ED levels would be more economical. You'd gain more.
I wonder if the 2 grams a week guys would do better on 1 gram injected every day vs. 3x a week.
DAY INJECT TOTAL
1 250 238
2 0 207
3 0 180
4 250 394
5 0 343
6 0 299
7 250 498
8 0 433
9 0 377
10 250 566
11 0 493
12 0 429
13 250 611
14 0 532
15 0 463
16 250 640
17 0 558
18 0 485
19 250 660
20 0 575
21 0 500
22 250 673
23 0 586
24 0 510
25 250 681
26 0 593
27 0 518
28 250 687
29 0 598
30 0 521
and so on.
I used this web calc for these figures:
http://www.roidcalc.com/
OR
http://www.powerboard.se/roidcalc/
The goal of injecting steroids is to increase blood levels of testosterone much higher than can be achieved normally. One of our criteria in doing this is to keep blood levels as stable as possible throughout cycle to provide the best environment for growth and to avoid as many sides as possible. I believe many side effects are caused by the spikes and dips created by once or twice a week injections, even using long esters. A way to reduce these sides would be to use a proper half life to determine when to inject or more importantly how much to frontload with.
Now most half lives are calculated on 1.5 x the number of carbon atoms to determine 1/2 life in days. That’s wrong! If you go to PubMed or AMJ you can look up numerous studies showing a much shorter half life(@ .7 per carbon atom)
That difference is because esters decay at a logarithmic rate, meaning the more esterified hormone in the injection depot, the more is released. This release rate slows as the amount of esterified hormone in the depot is reduced over time.
The general rule is about 0.7 X the number of carbons atoms in a linear ester . However when the body builder needs to keep in mind is that the majority of the esterified hormone is released, regardless of the ester, with the first 24hrs of injection because of the logarithmic rate of decay.
What does this mean in simple terms?
I'll use Testosterone Enanthate in an 8 week cycle as an example:
Assume a 5 day half life for Enanthate based on .7 x it's carbons.
Injecting 579mg on day one of your cycle will provide stable levels of 550 mg per week for the duration of your cycle provided you replenish 75 mg EVERY DAY.
INJECT
Day 1- 579- giving you 550 mg in 24 hours
Day 2 75 giving you 550 mg
Day 3 75 550
Day 4 75 550
Day 5 75 550
Day 6 75 550
Day 7 75 550
Day 8 75 550
Day 9 75 550
Day10 75 550
Day11 75 550
Day12 75 550
and so on until day 57 when you stop injections
decay clearance is as follows
DAY Total MG
58 479
59 417
60 363
61 316
62 275
63 240
64 209
65 182
66 158
67 138
68 120
69 104
70 91
71 79
72 69
73 60
74 52
75 45
76 40
77 34
78 30
79 26
80 23
81 20
82 17
83 15
84 13
85 11
all the way down to day 98 (end of week 14) before the Enanthate is totally cleared
--------------------------------------------------------------------------------
Enanthate Clearance 500 mg
Now let's look at 1 shot of Test Enanthate of 500mg taken on day one.
It will take 8 weeks to clear (assuming a 5 day 1/2 life)
DAY Injected 500 mg(level)
1 500
2 475
3 414
4 360
5 313
6 273
7 238
8 207
9 180
10 157
11 136
12 119
13 103
14 90
and so- on until week 9 when it reaches 0.
--------------------------------------------------------------------------------
Enanthate injected E3D at 250 mg-levels
Now lets look at Injections of Test Enanthate every 4 days with 250 mg.
Blood levels are all over the place and create many dips and spikes.
Not a prime anabolic environment. It takes 7 days and 3 injections to even get to 500 mg(498) and then continues to dip and spike the 500 mark until week 4 but then the spikes are over 600 mg. This daily fluctuation cannot be good for combating sides or keeping steady growth rate.
The other way to look at it is $$$$. 500 ED levels would be more economical. You'd gain more.
I wonder if the 2 grams a week guys would do better on 1 gram injected every day vs. 3x a week.
DAY INJECT TOTAL
1 250 238
2 0 207
3 0 180
4 250 394
5 0 343
6 0 299
7 250 498
8 0 433
9 0 377
10 250 566
11 0 493
12 0 429
13 250 611
14 0 532
15 0 463
16 250 640
17 0 558
18 0 485
19 250 660
20 0 575
21 0 500
22 250 673
23 0 586
24 0 510
25 250 681
26 0 593
27 0 518
28 250 687
29 0 598
30 0 521
and so on.
I used this web calc for these figures:
http://www.roidcalc.com/
OR
http://www.powerboard.se/roidcalc/
