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  1. #1
    MuscleChemistry Junior Member Board Certified Psy.D
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    Bump, I would like to know too.
    Thate

  2. #2
    MuscleChemistry Registered Member Board Certified Psy.D
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    I just stop fina... My body can't take that sh*t. But I am runnin Liquidex, Nolva, and towards the end of this cycle I am gonna throw in Proviron to harden up a bit.

    CJ
    "It ain't braggin' mutha fu@ker if ya back it up!"

  3. #3
    MuscleChemistry Guru Board Certified MD
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    Mifepristone (Mifeprex) is a true antiprogesterone but currently is used as a aborifacient so it's not avalible in pharmacies,only by physcian purchace from the distributor(Danco). That's politics for ya.
    Investigationally,monoclonal anti-progesterone antibody (DB3) (model 1), or progesterone receptor antagonists ZK98,299 (ZK299) show promise in animal models.

    Using winstrol as an antiprogesterone is wishful thinking and anecdotal at best. It makes no biochemical sense IMO.

    Heres a recent study on Mifeprex and its effect on the progesterone receptor. It does upregulate the estrogen receptor and so must be combined with an adequate aromatase inhibitor or Nolva.


    Administration of an antiprogesterone up-regulates estrogen receptors in the endometrium of women using Norplant: a pilot study.

    OBJECTIVE: To determine the effect of a single dose of mifepristone (200 mg) on endometrial estrogen and progesterone receptors in Norplant users. DESIGN: A prospective single-blind placebo-controlled pilot study. . INTERVENTION(S): Endometrial biopsies were taken after treatment with both placebo and 200 mg of mifepristone, both given at the start of a bleeding episode. MAIN OUTCOME MEASURE(S): Expression of endometrial progesterone (PR) and estrogen (ER) receptors, ovulation, and vaginal bleeding. RESULT(S): Mifepristone administration was associated with down-regulation of PR receptor subtype B and up-regulation of ER.
    . CONCLUSION(S): The effect of mifepristone on endometrial steroid receptors was consistent with functional inhibition of progesterone. The findings warrant further investigation of this regimen as a strategy to reduce frequent bleeding.


    Fertil Steril 2002 Feb;77(2):366-72 (ISSN: 0015-0282)
    Glasier AF; Wang H; Davie JE; Kelly RW; Critchley HO
    Department of Obstetrics and Gynaecology, Centre for Reproductive Biology, University of Edinburgh, 37 Chalmers Street, Edinburgh, EH9 3ET, Scotland, UK. a.glasier@ed.ac.uk
    This post not intended to provide medical advise,only entertainment and information. DecaDent does not advocate illegal activities and assumes no liability for information in this post. You should consult appropriate medical and legal authorities if uncertain about material in this post. FUCK WHAT PEOPLE SAY,GROW AS BIG AS YOU WANT.

  4. #4
    MuscleChemistry Guru Board Certified MD
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    Yeap! Basicly there are no readily avalible antiprogesterone agents. Period.
    There is enough money to be made in the antiprogesterone market that if winny was even remotely effective at blocking the PR then someone somewhere would be working on it or an analog...and no one is. The 3 agents..one a monoclonal anti-progesterone antibody (DB3) , and the two progesterone receptor antagonists RU486 or ZK98,299 (ZK299) are the only players in the game as of now,that I'm aware of.

    So to summarize,it sux huh.
    This post not intended to provide medical advise,only entertainment and information. DecaDent does not advocate illegal activities and assumes no liability for information in this post. You should consult appropriate medical and legal authorities if uncertain about material in this post. FUCK WHAT PEOPLE SAY,GROW AS BIG AS YOU WANT.

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