Thread: MPS - Muscle Protein Synthesis
06-18-2019, 07:50 AM #1
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MPS - Muscle Protein Synthesis
MPS (muscle #proteinsynthesis or #myofibrillarprotein synthesis) is a measure of how your muscles take up protein from the blood at add to their mass.
After a workout when protein is consumed, many studies use MPS to draw conclusions about where something is good or bad for increasing muscle mass.
The problem is many studies measure this effect in the short term and assume that this increase in MPS will persist or at least lead to more muscle mass in the long term.
A study investigating how well MPS predicts long term #muscle#gainsfollowed 23 #untrained men doing a 16 week upper/lower body split 4 times a week with linear progression from 12RM och 6RM. Subjects were given #protein, carb and fat #supplements after their #workoutsand on the morning of rest-days and their #musclemass was followed using MRI (gold standard).
The study found no significant or relevant correlation between MPS 6h post-workout and the amount of muscle gained (1). Thus short-term MPS should not be used to draw long-term conclusions.
Before you go thinking that MPS is completely useless remember that optimizing MPS may still meam that you build a tiny amount of additional muscle mass that simply isn't detectable in a study on 23 men. Small effects on muscle size are difficult to prove statistically and would probably require a study population of over 1000 people. Thus MPS os stil useful, but probably mostly for #bodybuilderslooking to add that last % to their #physique.
This doesn't either exclude the fact that the effect of whey protein/#BCAAs may still have an effect, as the population was untrained and, although unlikely from this result of this study, well trained people may still build more muscle than they otherwise would've if they didn't take whey/BCAA (2).
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1: Mitchell et al. PLoS One. 2014. .
2: Pasiakos. Sports Med. 2015.