1. #1
    MuscleChemistry Sales & Marketing Manager Board Certified MD
    jimbosmith316's Avatar
    Join Date
    Apr 2014
    Location
    Georgia
    Posts
    2,060
    Rep Power
    2147485717

    Default Ligandrol (LGD-4033)

    By Larry Holman June 28, 2018



    Whatís the biggest dilemma in the fitness industry? You guessed it right, losing fat while building more muscles. If youíve been working out long enough, youíve probably come across this situation. Months and months of bulking just to be stuck in the worst crosspoint for a bodybuilder: a body thatís well built in terms of muscles while being entirely covered in fat.


    What is the LGD-4033?

    Ligandrol is an oral nonsteroidal SARM that was first discovered by Ligand pharmaceuticals and thatís currently under development by Viking Therapeutics.


    How does it work?

    Just like any other SARM, the LGD-4033 selectively binds to specific androgen receptors that are found in muscles. Androgen Receptors or ARs are ubiquitous in the body, but Ligandrol isnít compatible with those found in the eyes or other androgen-rich organs. Being receptor-selective, this substance can be taken orally.


    Pros and Cons

    Sadly, there arenít many studies about Ligandrol, thatís why itís a controversial subject amongst experts. Athletes, bodybuilders, and powerlifters widely use this substance as it has a plethora of benefits with so little side effects that must be noted whatsoever.

    1. It boosts muscle growth


    LGD-4033 is known to increase T levels in the body, which promotes muscle growth and development. According to a placebo-controlled study published on PubMed, this substance can increase lean body mass, aka muscles, and strength, by mimicking the beneficial effects of natural androgen hormones. These effects include rising the anaerobic cycle and energy production process as well as facilitating blood circulation.
    2. It increases energy production and anabolic activity

    Anabolicum increases energy production, but that alone can cause a severe muscle loss. The key here is that this substance also increases anabolic activity which compensates the energy loss and results in a leaner body with minimal fat.
    3. No steroids side effects

    Prostate cancer is one of the most dangerous side effects of steroids and testosterone. Luckily, LGD-4033 and the other SARMs are selective and only affect some tissues in the body, including muscles and bones, which results in reducing the risk of developing muscle waste diseases like cancer and osteoporosis. Besides, other steroid effects arenít likely to develop when you consume SARMs, so thereís no risk of acne and hair loss, and no estrogenic effects like high blood pressure and water retention.
    4. No injections included

    Unlike steroids, you donít need to inject anything into your body. LGD-4033 can be taken through your mouth, which increases its acceptability among people. Thatís because, as mentioned several times above, itís selective, so you donít have to inject it directly into your muscles. Steroids, on the other hand, can enter any cell in the organism, thatís why one cannot take it through the mouth as it can get to tissues where it shouldnít be. Whatís even better is that despite being an oral medication that passes through the liver, it isnít hepatotoxic.
    Side effects?

    SARMs look perfect, I know. But as appealing as it may seem, LGD-4033 does have some side effects. Thankfully, they are minimal, even non-existent, and shouldnít represent a problem if youíre not suffering from an allergy or an exceptional condition. These side effects include headaches, nausea, and fatigue. Besides, most studies about Ligandrol showed that itís 100% safe and tolerable in most cases. In other words, itís the perfect medication for those seeking steroid benefits without dangerous side effects.
    What dose should you take?

    If youíre just starting out with Ligandrol, you can begin with a 5mg dose, then increase it accordingly. If you have a big build, you can go with a higher intake. 10mg every 24h-36h period is the most used dose for Anabolicum, while some go for as high as 20mg per day with little to no negative consequences.
    Several studies have shown that LGD-4033 could give significant results, aka increase lean mass, within a two-week to three-week period, which is impressive for a supplement.
    Is LGD-4033 stackable?

    Even though itís perfectly fine on its own, Ligandrol can be stacked with other SARMs, like Cardarine, Ostarine, and Testolone, to meet personal needs and goals. If youíre planning to take LGD with other products, make sure to adjust your daily intake accordingly, but consider increasing your Anabolicum dose instead of combining different SARMs.
    Whatís comforting is that LGD has virtually no side effects and studies have shown that itís tolerable for all doses.
    Likes Presser liked this post
     

  2. #2
    Presser's Avatar
    Join Date
    May 2002
    Posts
    40,501
    Rep Power
    2147524170

    Default

    Jimbo, you are a stud dude!
    Thanks jimbosmith316 thanked for this post
    Likes jimbosmith316 liked this post
     
    Author: Ben Presser
    Ph.D. P.E.D. Kinesiology
    Intramuscular Injection Certified

    MuscleChemistry Store

  3. #3
    MuscleChemistry Sales & Marketing Manager Board Certified MD
    jimbosmith316's Avatar
    Join Date
    Apr 2014
    Location
    Georgia
    Posts
    2,060
    Rep Power
    2147485717

    Default

    Quote Originally Posted by Presser View Post
    Jimbo, you are a stud dude!
    That's what that stuff does to you!

    Sent from my SM-N950U using Tapatalk
     

  4. #4
    MuscleChemistry Sales & Marketing Manager Board Certified MD
    jimbosmith316's Avatar
    Join Date
    Apr 2014
    Location
    Georgia
    Posts
    2,060
    Rep Power
    2147485717

    Default

    Bump

    Sent from my SM-N950U using Tapatalk
     

Tags for this Thread

Posting Permissions

  • You may not post new threads
  • You may not post replies
  • You may not post attachments
  • You may not edit your posts
  •  

Log in

Log in