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    Default THE LIBIDO PEPTIDE PT-141 (Bremelanotide)

    HAVE YOU HEARD ABOUT 'THE LIBIDO PEPTIDE'!?

    Posted by Paris H

    One of the best research peptides for sexual stimulation/arousal, here’s a little info, please enjoy.
    PT-141 (Bremelanotide) is the first of a new class of drugs called melanocortin agonists being developed to treat sexual dysfunction. The mechanism of action of PT-141 may offer significant safety and efficacy benefits over currently available products because it acts on the pathway that controls sexual function without acting directly on the vascular system.
    Clinical data indicates that PT-141 may be effective in treating a broad range of patients suffering from Erectile dysfunction. Erectile dysfunction is defined as the consistent inability to attain and maintain an erection sufficient for sexual intercourse. The condition is correlated with increasing age, cardiovascular disease, hypertension, diabetes, hyperlipidemia and smoking. In addition, certain prescription drugs and psychogenic issues may contribute to ED. It is estimated that some degree of ED affects one half of all men over the age of 40 and that 150 million men worldwide suffer from erectile dysfunction.
    In studies, bremelanotide was effective in treating sexual dysfunction in both men (erectile dysfunction or impotence) and women (sexual arousal disorder). Unlike Viagra and other related medications, it does not act upon the vascular system, but directly increases sexual desire via the nervous system.
    Women can become highly aroused when using this peptide as shown in a study by Palatin Technologies (NJ- U.S.A). Studies concluded that there was a change in vaginal pulse amplitude during neutral and erotic videos after treatment with bremelanotide or a placebo and subjects’ perceptions of physiological and sexual response within 24 hours of treatment with bremelanotide or placebo.
    RESULTS: More women reported moderate or high sexual desire following bremelanotide treatment vs. placebo and a trend toward more positive responses regarding feelings of genital arousal occurred after bremelanotide compared with placebo. Among women who attempted sexual intercourse within 24 hours after treatment, significantly more were satisfied with their level of sexual arousal following bremelanotide.

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    PT-141, 10mg (Bremalanotide)Information


    PT-141 (Bremelanotide) originally developed from the peptide known as Melanotan 2(MT-II) is the generic term for a new pharmaceutical grade synthetic aphrodisiacresearch peptide. It has been developed to address Erectile/Sexual Dysfunction orimpotence in men, as well as sexual dysfunction in women (sexual arousaldisorder). More than 40 per cent of women suffer from 'female sexual dysfunction'.PT-141 is the only synthetic aphrodisiac. Unlike Viagra and other related medications(PDE5s), PT-141 does not act upon the vascular system, but directly through thenervous system (hypothalamus) to increase desire. Viagra, Cials and Levitra are notconsidered aphrodisiacs as they do not have any direct effect on the libido.However, treatment with PDE5 inhibitors and PT-141 are known to have asynergistic effect.Originally, the peptide Melanotan II that bremelanotide was developed from wastested as a sunless tanning agent. In initial testing, Melanotan II did induce tanningbut additionally caused sexual arousal and spontaneous erections as unexpected side effects in eight out of the ten original male volunteer test subjects. In clinical studies,bremelanotide has been shown to be effective in treating male sexual and erectiledysfunction as well as female sexual dysfunction. It is currently being tested byPalatin Technologies (you will find the fact sheet on PT-141 by Palatin Technologiesbelow).Bremelanotide is a cyclic hepta-peptide lactam analog of alpha-melanocytestimulatinghormone (alpha-MSH) that activates the melanocortin receptors MC3-Rand MC4-R in the central nervous system. It has the amino acid sequence Ac-Nlecyclo[Asp-His-D-Phe-Arg-Trp-Lys]-OHor cyclo-[Nle4, Asp5, D-Phe7, Lys10]alphaMSH-(4-10).PT-141 is a metabolite of Melanotan II that lacks the C-terminal amidefunction. Its molecular formula is C50H68N14O10 with a molecular weight of 1025.2.In the United States it is currently in a Phase III clinical trial.


    How does it come?

    Bremelanotide PT-141 Peptide comes in 10mg vials. As a lifestyle peptide, the 10mgproduct is a lot to consume and may offer up to 20 doses when dosing light. The PT-141 peptide reconstituted with bacteriostatic water remains potent in the fridge formonths.Currently the nasal and oral routs have not been made effiecient and any nasalsprays, pre-mixed PT-141, pills and loose powder are not legitimate. There aresuccessful reports of snorting and nasal spray experiences...however they are fewand far between. PT-141 is a sterile injectable made for sub-q injection (like insulin). Bremelanotide is injected (subcutaneously) and opens awindow of possibilities, desire, and strength for you acouple of hours later. PT 141 has a unique window ofopportunity lasting six to 72 hours and should beadministered 2-4 hours before you are wanting to feelthe effects of the peptide.

    DOSING0.30 mg (trial)0.70 mg (average)1 mg (optimal)1.5 mg (strong)2mg (extra strong)

    Does this help give erections or just put you inthe mood?


    With PT-141, you feel good, not only sexually aroused,” reported anonymous patient007, a participant in a Phase 2 trial, “you feel younger and more energetic.” Saidanother patient: “It helped the libido. So you have the urge and the desire. . . . You getthis humming feeling; you’re ready to take your pants off and go.” And another: “Twice my wife and I had sex twice in one night. I came in [to work] and I just ravedabout it: ‘Jesus, guys . . . 58 years old and you don’t do that.’ ” Tales ofpharmaceutically induced sexual prowess among 58-year-olds are common enoughin the age of the Little Blue Pill, but they don’t typically involve quite so urgent arepertoire of humming, throbbing, tingling, and double-dipping. Or as patient 128 putit: “My wife knows. She can tell the difference between Viagra and PT-141.”The precise mechanisms by which PT-141 does its job remain unclear, but the roughidea is this: Where Viagra acts on the circulatory system, helping blood flow into thepenis, PT-141 goes straight to the brain itself. And there it goes to work, switching onthe same neural circuitry that lights up when a person actually, you know, wants to.Basically this takes men back to middle school. You may find yourself in a similarsituation as you were in 8th grade science class with the teacher bent over helpingthe student in front of you. It may be necessary to do a “tuck up” if at theoffice…especially at the public pool!Women state that the sensation given from injecting PT-141 is like being in heat! Onecolleague in particular stated that she didn’t know what was going on…but she hadwanted “it” all day long after dosing the night before


    Is there any reconstituting involved?

    YesBacteriostatic water is the recommended mixing porduct however this product is aprescrption only product and hard to get. You can currently purchase it on eBay foraround $30 a vial however sterile water can be used..To mix the vial with bac water, take one syringe and grab your vial of bacteriostaticwater. If using a 1 cc syringe (100 units), use the syringe to withdraw 1 full ml (1cc)and inject that into the vial of PT-141 through the rubber. Be sure to aim the needletowards the glass, so that it will trickle down and not harm the peptide. Swirl the vialto thoroughly mix and let the peptide dissolve. The key here is to be gentle.If you have your vial of PT-141 stored in the freezer, move the vial of PT-141 to fridgethe night before you plan on reconstituting it so that when you mix it it is the sametemperature refrigerated bac water with the PT-141 which is the most efficientmanner. Just some tricks of the trade here!So now you have 100 units (1cc) of bacteriostatic water mixed with 10 mg of PT-141in your vial ready to go. A 1mg dose would be 10 units or .1ml (.1cc). Make sense?Hope so.PT141 reconstituted with bacteriostatic water remains preserved for 6-12 months and a month in the refrigerator when mixed with sterile water before it begins todegrade. We recommend preloading your syringes and storing them in the freezer ifyou are reconsituting with sterile water instead of bac water.

    How should PT-141 stored?

    Vials are freeze-dried and therefore will remain stable at room temperature for 1-2months. However, for long-term storage they should be stored in the freezer, wherethey will remain stable for up to 24 months in powder form. Once mixed with itshould be stored in the fridge and not left at room temperature! It will last 1 month ifyou have reconstituted with sterile injectable water and 6-12 months if you haveused bacteriostatic water. We recommend preloading your syringes if you are usingsterile injectable water and freezing them. This will prolong the life of your PT-141. DONOT preload if you are using bac water.

    Pick Up Something ​Heavy

  2. #2
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    i edited your title so the actual name of the peptide was in title, so its indexed and found on search engines now. thnx
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    Author: Ben Presser
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    If anyone has tried PT141 please share ur experiences
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    I have not, but i have written an article on it that can be found here and meso a couple years back.
     

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    Wouldn't mind trying this stuff out along M-II. Let's get these peptides in the MC Store!
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    You might wanna try Enhanced Peptides. They might have one or both of those items brutha.
    Author: Ben Presser
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    Oh no shit?! I had no idea. Totally stoked thx bro!
     

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    Put in an order with those guys. Will let y'all know how it goes.
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    Quote Originally Posted by NAIR View Post
    Put in an order with those guys. Will let y'all know how it goes.
    Did you tell them I sent you ? You get a complimentary hand job
    Thanks NAIR thanked for this post
     
    Author: Ben Presser
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    No, but they may have given me one anyway because I did 2mgs today and don't feel shit.
     

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    lol, well maybe youll get a tan out of it lol
    Author: Ben Presser
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