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07-12-2017, 10:54 AM #1
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Melanotan 2: Burn Fat, Get Tan and Have Fun
Melanotan 2: Burn Fat, Get Tan an Have Fun Melanotan 2(MT2) is a synthetic cyclic heptapeptide that is mainly used to increase tanning. It stimulates a natural increase in melanin production. Melanin is the main determinant of skin color in humans. Melanin is a brown pigment which causes skin to become darker in appearance when exposed to UV rays.
Melanotan II was first synthesized at the University of Arizona when looking at possible ways to treat skin cancer. They hypothesized that an effective way to reduce skin cancer rates in people would be to induce the body's natural pigmentary system to produce a protective tan prior to UV exposure.
Clinical trials have shown that Melanotan 2 safely promotes melanogenesis. This is a process were melanocytes produce melanin. Lighter-skinned people have low base levels of melanogenesis. Exposure to UV-B radiation causes an increased melanogenesis. The purpose of the melanogenesis is to protect the hypodermis, the layer under the skin, from the UV-B light that can damage it. It does this by absorbing all the UV-B light and blocking it from passing the skin layer.
MT2 has also been shown to have aphrodisiac effects. Giuliano F et al. (2006) showed MT2 exerting a dose-dependent effect on erections in asthetized rats. They went on to show MT2 having inducer and facilitator activities on erection depending upon delivery route of the peptide. There are various studies showing similar results in both animals and humans. Wessells H et al. (2000) highlighted the positive effect MT2 has on sexual desire and erections in men suffering with erectile dysfunction and various organic risk factors.
Through clinical research it has been shown MT2 has excellent fat burning effects. It was previously thought that it assisted weight loss indirectly due to its appetite-reducing effect. However, it now appears that MT2 has direct fat burning effects. Strader AD et al. (2007) is a great example of the direct fat burning effect. They conducted a series of tests including one that shown MT2 treatment led to ageneral reduction in both visceral and subcutaneous fat tissue in high-fat-fed mice. Choi YH et al. (2003) also showed in addition to reducing food intake and inhibiting body weight gain, administration of MT2 reduces fat mass. They concluded this was most likely by accelerated lipid mobilization, but not by apoptosis (cell death).
A very interesting effect MT2 brings about is its ability to increase insulin sensitivity during researchers' trials. Heijboer AC et al (2005) studied the effects MT2 has on hepatic and whole-body insulin sensitivity. Results showed administration of MT2 increased insulin-mediated glucose disposal but did not affect the capacity of insulin to suppress EGP. MT2's acute effect on insulin sensitivity was further highlighted during studies done by the Nagoya University Graduate School of Medicine. Banno R et al. (2007) examined the effects MT2 had on insulin sensitivity in diet-induced obese rats. The insulin tolerance test showed that insulin sensitivity was significantly improved in the MT2 group compared to the pair-fed group. Furthermore, MT2 treatment increased the number of small-sized adipocytes in epididymal white adipose tissues, suggesting that MT2 increased insulin sensitivity through action on the white adipose tissues.
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08-11-2017, 03:25 AM #2
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I have used this. A few years back. It tanned me, it made me want sex a lot. It was like cialis for boners lmao, but it really didn't make my stomach feel good. Made me pretty sick. Some are good on it. But it just didnt like my digestive tract. I would shoot the minimum dose to see if it helped, but still, bad cramps and stomach issues. It does tan you and it does suppress appetite for me but it was hard to function at least for me.
I have no idea way. The tan can get deepppppp you can go fron albino to Ethiopian and if you have the same issue that I had with digestion and it made eating very very difficult well you'll turn into an Ethiopian muscle wise to if it gives you the same issues that I had I didn't use it for very long about 3 weeks I didn't use a lot to where I got super insanely dark but I did have a nice all over caramel tan which is not something I'm used to having I'm pretty white but I started losing muscle because I love and able to eat and it affected my training and I just continued it and I sold the extra bottle to a friend of mine who loved it he had no issues with it he absolutely loved it
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08-11-2017, 08:18 AM #3
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I found that if I took it right before bed that I didn't get that sick feeling. May help you.
LeatherHead liked this post
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08-11-2017, 11:17 AM #4
yes take it right before bed, and enjoy a great tan.
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08-11-2017, 11:56 AM #5
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08-11-2017, 05:50 PM #6
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I've used it plenty in the past, and actually getting ready to get some to get ready for this show. I took it right before bed, and never had the bubble guts or anything bad. I just kept getting darker and darker and darker. I usually do it in early spring, so as soon as the heat wave gets here in late February, I can be at the beach and not burn. lol
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11-30-2017, 08:34 PM #7
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