drtbear1967
Musclechemistry Board Certified Member
theguerillachemist
I've been getting a lot of questions about this newer SARM and so I've been trying to get as much research on it as possible.
LGD-3303(not ligandrol) is a SARM that seems to be very potent at activating the AR in muscle cells at very low doses. The study showed increased muscle mass in doses as little as 0.1mg/kg in rats. Unfortunately, it also seems to activate the AR in the prostate as well, especially at higher doses. But at the lower end, it seems to be more selective towards muscle tissue. The other bad thing about 3303 is that it seems to really suppress LH levels, especially any dose over 1mg/kg(in rats). It seems to have a half life of about 5-6hr before plasma levels rapidly drop off, so multiple dosing might be best.
Based on the limited papers I found, it seems like this is a very potent SARM that can add some serious size, especially in higher doses. However, be prepared to have a lot of suppression of natural test levels and required to use a strong PCT when stopping. This is not a "bridging" compound. As far as minimal effective dose, it seems that as little as 1-2mg a day are enough to increase size while minimizing the androgenic effects. Once you start dosing at 6mg and above, the suppression will be great and prostate growth was shown. I will continue to research this compound as more literature becomes available. Worth noting: LGD-3303 seems to have a very strong anabolic effect on bone density and increasing calcium uptake and increasing new bone cell generation.
I've been getting a lot of questions about this newer SARM and so I've been trying to get as much research on it as possible.
LGD-3303(not ligandrol) is a SARM that seems to be very potent at activating the AR in muscle cells at very low doses. The study showed increased muscle mass in doses as little as 0.1mg/kg in rats. Unfortunately, it also seems to activate the AR in the prostate as well, especially at higher doses. But at the lower end, it seems to be more selective towards muscle tissue. The other bad thing about 3303 is that it seems to really suppress LH levels, especially any dose over 1mg/kg(in rats). It seems to have a half life of about 5-6hr before plasma levels rapidly drop off, so multiple dosing might be best.
Based on the limited papers I found, it seems like this is a very potent SARM that can add some serious size, especially in higher doses. However, be prepared to have a lot of suppression of natural test levels and required to use a strong PCT when stopping. This is not a "bridging" compound. As far as minimal effective dose, it seems that as little as 1-2mg a day are enough to increase size while minimizing the androgenic effects. Once you start dosing at 6mg and above, the suppression will be great and prostate growth was shown. I will continue to research this compound as more literature becomes available. Worth noting: LGD-3303 seems to have a very strong anabolic effect on bone density and increasing calcium uptake and increasing new bone cell generation.
