Thanks for your input drab4. You're right: Wyeth did produce norbolethone but not commrecially. The reason for it not not being marketed is unclear, but not likely due its toxicity. It has actually been shown to oppose the toxic effects of many compounds/drugs: carbon tetrachloride , indomethacin, ethylene glycol, LSD, allopurinol, bishydroxycoumarin, phenyl isothiocyanate, haloperidol, proscillaridin, methylsalicylate, acrylonitrile, methaqualone, thioacetamide, digitoxin, aniline, cocaine, ketamine, parthion, and pesticides. It has very low androgenic properties and hence low incidence of androgenic side effects. It's sited side effects have been dysfuntional uterine bleeding in women (no suprise form such a highly anabolic steroid) and "liver damage" (not more than dianabol). It showed to be very promising in children with stunted growth, but growth hormone has replaced it. The fact that Norbolethone was never marketed has perhaps more to do with politics than side effects.