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Thread: M Sten MethylSten

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    Default M Sten MethylSten



    IGF-1 Sale!
    Methyl Stenbolone

    wre146.jpg

    Nomenclature:

    2,17α-dimethyl-5α-androsta-1-en-17β-ol-3-one, or 2,17a-Dimethyl-17b-hydroxy-5a-androst-1-en-3-one

    Anabolic/Androgenic Ratio:

    660:90-170 vs. methyltestosterone by oral administration. [1]

    Synonyms:

    Methyl stenbolone, methyl sten, 17a-methyl-stenbolone, m-sten, ultradrol

    History:

    In 1966, researchers at Searle Laboratories set about methodically testing the myotrophic (anabolic) and androgenic effects of a series of A-ring modified androstane derivatives [2]. The compounds they explored reads like a who's who of designer steroids.
    Methyl-1-testosterone (M1T), desoxymethyltestosterone (phera), 17a-methyl-1-androstenediol (Alpha One), and a variety of other 1- and 2-dehydro compounds were explored for activity.

    The researchers proudly announced that "Even the least active compound in Table 6 possessed a higher relative myotrophic potency than previously has been obtained with several clinically interesting compounds which have been studied under identical conditions, i.e. oxymetholone, oxandrolone, stanozolol, and methandrostenolone." (anadrol, anavar, winstrol, and dianabol).

    2cpclc9.jpg

    [2]

    Key:
    IIe = methyltestosterone
    IIa = methyl-1-testosterone
    IVd = methyl stenbolone
    IIf = alpha one (17a-methyl-1-androstenediol)
    IIIa = phera (desoxymethyltestosterone)

    As you can see from the table above, methyl sten has somewhere between 2/3 and 3/4 the anabolic activity of methyl-1-testosterone, and a similar A:A ratio (by oral administration to castrated rats).

    It can also be found in an earlier paper by two of the same authors [3], however at the time it was only studied for activity by intramuscular injection, so the figures it quotes are irrelevant for our purposes. It does, however, give a recipe for producing the compound from superdrol.

    281rkzq.jpg

    Methylsten™ is listed as one of the ingredients in a proprietary blend in a now-discontinued product called Mass Tabs by IDS, though testing has shown that this product (at least the later, bottled batches) in fact contained superdrol [4][5].

    Structure and Function:

    Structurally resembling the bastard child of M1T and superdrol, methyl sten is a DHT-derivative that is dimethylated at C-2 and C-17 (like superdrol) and has a 1-ene (like methyl-1-test).

    It's important to note that while methyl stenbolone is dimethylated at C-2 and C-17 like superdrol, the spatial configuration is different due to the presence of a delta-1 double bond (the C-2 methyl group is therefore planar). This means that methyl sten is a 2,17a-dimethyl rather than a 2a,17a-dimethyl compound.

    A more recent (2009) paper on the effects of structural modifications to steroids concluded that the addition of a 2-methyl function to a 1-ene steroid had little effect on the relative potency of the compound [6].

    fnfh4n.jpg

    [6]

    You'll note however that this is view is taken virtually word for word from the 1961 study that only examined the activity of the compounds by IM injection and is therefore questionable when discussing their oral activity.



    [3]

    Metabolism:

    Since it's DHT-derived, aromatisation is impossible. 5a-reduction is also impossible, since it's already 5a-reduced. The 17a-methyl group greatly increases the bioavailability of the compound by oral administration.

    The combination of delta 1-dehydrogenation and 2-methylation is likely to make the A-ring very resistant to metabolism. 3z-,16z-, and 18-hydroxylated metabolites are likely to be the only ones detectable after administration, other than the unchanged compound [7][8].

    Effects:

    It is a strong oral steroid in the vein of pheraplex, superdrol, and M1T. It should be an excellent bulking compound at an appropriate dosage.

    Side Effects:

    It is inevitable that the compound will display some degree of hepatotoxicity. This is discussed in some detail on the manufacturer's blog, which I would recommend reading [9].
    The standard list of steroidal side-effects listed in the other profiles will also apply to this compound.

    Recommended Dosages and Cycle Durations:

    These will be formed by the weight of public opinion after enough logs have been recorded. The only confirmed product on the market to contain this compound comes in 4mg caps and recommends dosing at two caps per day, and not to exceed three caps per day. It is likely in my opinion that the "standard dosing" will end up significantly higher (20mg+).
    Given that the level of liver toxicity is at this stage unknown, cycles should be kept to four weeks or less, as is usual with a strong methyl such as superdrol or M1T.


    References
    [1] Vida J.: Androgens and Anabolic Agents. Academic Press, New York (1969) p. 212.
    [2] Acta Endocrinol 1966 53 627-634 & 635-643
    [3] J. Org. Chem., 1962, 27 (1), pp 248–253
    [4] test results IDS mass tabs - ThermoLife International Forums
    [5] Affidavit for bodybuilding.com raid: image 1, image 2, image 3
    [6] Steroids 74 (2009) 172–197
    [7] J. Steroid Biochem. Mol. Biol. 115 (2009) 44-61.
    [8] J. Steroid Biochem. Mol. Biol. 101 (2006) 161–178.
    [9] Antaeus Labs: A few words on the hepatotoxicity of 17a-methylated androgens/anabolics


  2. #2
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    Looking at doing M-Sten over the summer. Would you recommend the stack IronMagLabs that they have listed with it?

    FIRST 4 WEEKS:
    M-STEN Rx - 2 caps daily (1 cap taken two times daily)
    4-Andro Rx - 2 caps daily
    Ultra Male Rx - 1 cap daily
    Advanced Cycle Support Rx - 2 caps daily
    LAST 4 WEEKS:
    Ultra Male Rx - 1 cap daily
    Advanced Cycle Support Rx - 2 caps daily
    E-Control Rx - 3 caps daily

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    i don't have any experience with it bro sorry but ill bump this up for those who know and can help ya out


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    I have to make a disclaimer.

    I have not taken M Sten.
    What I am going to explain to is based on my general knowledge of prohormones and designer steroids
    --------
    I need to know the actual MGs of the compound you plan on taking.
    The original M-Sten was dosed very low @ 4 mg/cap
    I have seen logs of experienced users running as high as 30 mg/day now

    I would not recommend any stack from a specific company.
    I would want to do my research.
    What are my goals? Cut/Bulk/Recomp
    I would then source my product from a reliable source usually on sale or for a good deal.

    Ultimately this will dictate my cycle depending on dosage acquired.
    I would generally preload support supplements for a week and then start low on all hormonal compounds.
    Week by week working my dosage up with NO sides. ****IF SIDES LOWER DOSE or STOP INCREASE

    FINALLY, That Post Cycle Protocol is terrible. Don't use it. Even if you decide to try this cycle. DO NOT USE PCT.
    Instead use a SERM. Check out the Muscle Chem Advanced Supplements Store!
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    bump for subaruski


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    Well I'm about to start the cycle below in a week or two. I will be adding clomid to my PCT. Any last min input would be awesome.

    Quote Originally Posted by Subaruski View Post
    Looking at doing M-Sten over the summer. Would you recommend the stack IronMagLabs that they have listed with it?

    FIRST 4 WEEKS:
    M-STEN Rx - 2 caps daily (1 cap taken two times daily)
    4-Andro Rx - 2 caps daily
    Ultra Male Rx - 1 cap daily
    Advanced Cycle Support Rx - 2 caps daily
    LAST 4 WEEKS:
    Ultra Male Rx - 1 cap daily
    Advanced Cycle Support Rx - 2 caps daily
    E-Control Rx - 3 caps daily

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    it looks fine. did you get all that in a kit/stack? DAA is something you might want to check into

    might want to start the cycle support a week early

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    Thanks for answering any of my questions above and responding in such a timely manner.
    This really allows me to give you an effective answer.
    Then along with your stats, members can help to predict your possible gains.

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    First of all why decide on M1T? It is a methylated prohormone version of Primobolan. You are taking a moderately anabolic and hardly androgenic steroid that is safe and taking the methylated version. 4 ANDRO is not methylated and safer. You are supposed to take 1-AD with 4 Andro. Scrap the m-sten. 1-AD or 1-androstene-3beta, 17beta-diol as it is known in the compound world is not a steroid, however it is a unique prohormone. It isn't the exact version of natural testosterone produced in the body but a likeness called 1-testosterone. 1-testosterone under a microscope differs from actual testosterone by a double bond isomer. As a complex compound they are both different. 1-testosterone is considered much more potent even passing the ranks of the popular anabolic steroid.

    You need to do a real PCT cycle after this cycle to keep gains and restore testosterone production to normal as quickly as possible. Do adex during the cycle and either clomid or nolvadex post. You might as well pin yourself with some hcg at least be a man and stick some proper pct in you. How old are you by the way? I don't think you are old enough to take this shit. You think this is a game but these prohormones are the real deal.
    4 ANDRO

    Serving Size: 1 Capsule
    Servings per Container: 60
    4-androstene 3b-ol, 17-one 50mg *
    6,7-dihydroxybergamottin 15mg *
    Piperine (Black Pepper extract) 5mg

    M-STEN
    Serving Size: 1 Capsule
    Servings per Container: 120
    2,17a-dimethyl-5a-androsta-1-en-17b-ol-3-one 4mg


    Low Quality Muscle

    Like any 17aMethyl steroid, the big problem with M1T is that any muscle gained is likely to be lost as soon as the steroid is stopped. This is because the 20lbs isn’t really “muscle” it is in fact cellular water (which is different from estrogen water retention). The common cycle of m1t is a gain of 18lbs and then a loss of 13lbs after the cycle which makes it fairly unpopular unless you are using it right before spring break. This muscle loss is an issue since everyone knows you are on steroids when you gain 20lbs in 2 weeks, only to lose 15lbs of that 2 weeks later. Unless you like being looked at as a “roid head” you will want to avoid M1T and other 17aMethyl steroids for this reason.

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    I'm 29 years old. Been lifting just over 2 years. 6'-3" 205lbs right under 15% bf. Goal is to add 10lb of muscle or so while dropping a few % of bf. Cycle listed is two 10mg daily.

    Quote Originally Posted by RagingWhoreMoan View Post
    Thanks for answering any of my questions above and responding in such a timely manner.
    This really allows me to give you an effective answer.
    Then along with your stats, members can help to predict your possible gains.
    Last edited by Subaruski; 02-15-2014 at 03:40 PM.

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    What are you taking for liver support?

    What is in the other products? Especially the E-Control?

    You have purchased SERM? In case sides flare up and you want to come off early always have SERM on hand

    You should be good to go otherwise

    I think your goals are very realistic. Bodyfat will be a function of diet. Eat a lot but eat clean.

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    Links to products:
    4-Andro Rx
    Ultra Male Rx
    Advanced Cycle Support Rx
    E-Control Rx

    Do you have a recommended SERM?

    As noted above I'll adding in liquid Clomid in the PCT weeks 5-8. Should I taper the dose off gradually or just 1ml daily until end of PCT?

    Quote Originally Posted by RagingWhoreMoan View Post
    What are you taking for liver support?

    What is in the other products? Especially the E-Control?

    You have purchased SERM? In case sides flare up and you want to come off early always have SERM on hand

    You should be good to go otherwise

    I think your goals are very realistic. Bodyfat will be a function of diet. Eat a lot but eat clean.
    Last edited by Subaruski; 02-15-2014 at 03:54 PM.

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    When does cycle start ?
    preload cycle support for a few days for Bp

    only take ultra male is pct... Natty test is shut down
    you could up dose to two caps then

    Taper nolva 40/30/20/10

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    Looking to start in a week or two so I can definitely start cycle support in the next few days. 2 caps daily sufficient for front load?

    Why only take ultra male on PCT and not with cycle?

    Was thinking 2x10mg daily was plenty for a first timer?

    Taper clomid similar to nolva dosage?

    Quote Originally Posted by RagingWhoreMoan View Post
    When does cycle start ?
    preload cycle support for a few days for Bp

    only take ultra male is pct... Natty test is shut down
    you could up dose to two caps then

    - - - Updated - - -

    I taper nolva

    - - - Updated - - -

    I taper nolva
    Last edited by Subaruski; 02-15-2014 at 04:10 PM.
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