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    Default T3 & T4 with Steroid Cycle for Fatloss. T3, Clen, Anavar Cycle

    T3 & T4 with Steroid Cycle for Fatloss. T3, Clen, Anavar Cycle

    IGF-1 Lr3 Bulk Special!!!!

    T3 & T4 with Steroid Cycle for Fatloss. T3, Clen, Anavar Cycle

    T3 info, good data

    for T3, T4, Clenbuterol and All Your Research Chemical & Peptide Needs!



    T3 is not a drug that should be taken lightly. It's a very potent thyroid hormone. Messing with your natural hormone levels is very dangerous and unpredictable. The potential for complications is very high, and abuse can lead to thyroid disease and low thyroid output not only immediately upon discontinuation, but also later in life.

    There is no such thing as safe use of T3 outside of a medical setting. There is only "safer" use. Use at your own risk.

    Introduction: What is T3 and what are the side effects?

    This article is pushing 2000 words, so here's a link for anyone who's interested: http://arbl.cvmbs.colostate.edu/hbo...roid/index.html

    What about T4?

    Bodybuilders should not use T4. It's a much weaker drug designed for long term use in patients with chronic thyroid disease. 100mcg of T4 corresponds to 25mcg of T3 and offers equivalent thyroid support; however, this does not translate to equal weight loss benefits. It has made itself on sources' lists simply because it is widely available and extremely cheap.

    Is T3 catabolic?

    It may shock many people to know that T3 is NOT catabolic per se. Corticosteroids are catabolic drugs that attack muscle tissue directly; T3 does not. It is a very potent calorie burner and it does not discriminate between carbohydrates, protein and fat. Unlike DNP, it has no protein sparing properties. T3 is also more likely to burn muscle than fat in lean users (10-12% BF), but this can be said for any extreme drop in caloric intake and uptake such as starvation diets (Caloric intake <10 X BW).

    Muscle loss can be avoided with the use of anabolic agents. T3's alleged catabolic properties have become legendary. Excessive amounts of T3 (more than 75mcg), will have a very strong calorie burning effect, and since some bodybuilder use 150 mcg, it's easy to see why such misinformation has been so prevalent. The average bodybuilder will not need several grams of steroids to counter a reasonable dose of T3. There is no need to use more than 75mcg-100mcg. Going beyond this dose will cause more harm than good, as massive doses of steroids need to be used to counter the muscle loss, further stressing the body for minimal, if any additional benefits.

    I think I've lost 20 lbs of muscle!

    T3 can also give your muscles an extremely flat look and very soft feel. This side effect of extreme glycogen depletion can have a very profound psychological impact in bodybuilders. It often feels and looks like muscle loss when it's simply a lack of muscle "pump" because of restricted blood flow to that area and depletion of glycogen stores in muscles. Generally, carbohydrate loading does not solve this problem. "Pumping up" (or training for that matter) brings more blood into the muscles and is a temporary albeit effective solution. Clenbuterol and certain steroids can offset the lack of muscle pump because these drugs tend to "harden up" users by bringing more blood into to the muscles.


    Are steroids absolutely necessary on T3?

    This is very dependent on the user. Diet must be flawless, only reasonable doses should be considered (50mcg) and the user must know his body to a tee. Those who don't know what that last statement entails should not even consider T3. This is a veteran drug and should not be used by bodybuilders who are new to the game or do not have a deep understanding of how there bodies react to certain foods and training philosophies.

    T3 can be used alone or better yet with Clenbuterol without fear of muscle loss in overly fat people (20-25% BF). This is not recommended, however, since these people will generally return to overeating upon discontinuation of their cycle and may likely end up with more weight than they started with.


    How should I eat on T3?

    Protein should be kept at 1.5-2g per lb of bodyweight. The majority of protein should come from lean meats. Shakes can be used, but should not be heavily relied on as they are more likely to be turned into glucose and used immediately for energy. Caloric reduction should come from carbs and fat only.


    What is T3 used for?

    Fat-loss: The main use for T3.

    Increase Nutrient Uptake: Not very well known, but this is a great use for T3. Doses between 6.25-12.5mcg do not shutdown endogenous thyroid output. T3 at this dose can be used to add LBM and help in keeping the fat off. When doses are kept at 6.25-12.5mcg, muscles are full and rock hard, and energy is through the roof. At these light doses, it's common for people to go to the bathroom 5-6 times a day because there bodies are making more efficient use of the food they eat.

    Can I permanently shutdown my Thyroid?


    Simply put, NO, it can't happen. Natural thyroid production will be completely shutdown for a good period of time after using T3, but it will eventually recover. Bruce Kneller posted this study on the Testosterone website:

    N Engl J Med 1975 Oct 2;293(14):681-4
    Recovery of pituitary thyrotropic function after withdrawal of prolonged thyroid-suppression therapy.
    Vagenakis AG, Braverman LE, Azizi F, Portinay GI, Ingbar SH.

    The pattern of thyrotropin secretion was analyzed in seven euthyroid women, before and after withdrawal of long-term thyroid hormone, by serial measurements of thyroid 131l uptake, serum thyroxine, tri-iodothyronine, and thyrotropin concentrations, and the response to thyrotropin-releasing hormone. During exogenous hormone administration, 131l uptake was suppressed, and serum thyrotropin concentrations before and after administration of thyrotropin-releasing hormone were undetectable.
    After withdrawal of exogenous hormone, thyrotropin secretory function was transiently impaired, as indicated by undetectable basal thyrotropin concentrations together with absence of response to thyrotropin-releasing hormone, and subsequently by normal values of basal thyrotropin concentration and normal responses to releasing hormone while serum thyroxine and tri-iodothyronine concentrations were subnormal.
    Decreased thyrotropin reserve persisted for two to five weeks. Detectable values of serum thyrotropin (less than 1.2 muU per milliliter) and a normal 131l uptake usually occurred concurrently in two to three weeks. Serum thyroxine concentration returned to normal at least four weeks after hormone withdrawal.

    Basically, it is extremely important to eat cleanly and keep up with cardio for at least 4 weeks and up to 6 weeks following a T3 cycle. It's also very important to ramp down properly and not use any drug that have an effect on metabolism and thyroid function, i.e. Clen, Ephedrine, Steroids, DNP, T2€

    Calories should be kept in check, even lowered in some cases, and High Intensity Cardio is a must; at least 20mins, 3times a week. L-Tyrosine can be used at 1-3g a day to help thyroid function, but its effectiveness is debatable.

    Switching to a higher carb, lower fat and lower protein diet is crucial in helping your thyroid bounce back after a cycle. A three-day carb up would be a good idea following a T3 cycle. This study demonstrates how important carbohydrates are for normal thyroid function. (Note: Some people seem to think of carbs as Lucky Charms and toast when there are far better carb choices that won't make you look like the Michelin Man.)

    Dietary-induced alterations in thyroid hormone metabolism during overnutrition.
    Danforth E Jr, Horton ES, O'Connell M, Sims EA, Burger AG, Ingbar SH, Braverman L, Vagenakis AG.

    Diet-induced alterations in thyroid hormone concentrations have been found in studies of long-term (7 mo) overfeeding in man (the Vermont Study). In these studies of weight gain in normal weight volunteers, increased calories were required to maintain weight after gain over and above that predicted from their increased size. This was associated with increased concentrations of triiodothyronine (T3). No change in the caloric requirement to maintain weight or concentrations of T3 was found after long-term (3 mo) fat overfeeding. In studies of short-term overfeeding (3 wk) the serum concentrations of T3 and its metabolic clearance were increased, resulting in a marked increase in the production rate of T3 irrespective of the composition of the diet overfed (carbohydrate 29.6 +/- 2.1 to 54.0 +/- 3.3, fat 28.2 +/- 3.7 to 49.1 +/- 3.4, and protein 31.2 +/- 2.1 to 53.2 +/- 3.7 microgram/d per 70 kg). Thyroxine production was unaltered by overfeeding (93.7 +/- 6.5 vs. 89.2 +/- 4.9 microgram/d per 70 kg). It is still speculative whether these dietary-induced alterations in thyroid hormone metabolism are responsible for the simultaneously increased expenditure of energy in these subjects and therefore might represent an important physiological adaptation in times of caloric affluence. During the weight-maintenance phases of the long-term overfeeding studies, concentrations of T3 were increased when carbohydrate was isocalorically substituted for fat in the diet. In short-term studies the peripheral concentrations of T3 and reverse T3 found during fasting were mimicked in direction, if not in degree, with equal or hypocaloric diets restricted in carbohydrate were fed. It is apparent from these studies that the caloric content as well as the composition of the diet, specifically, the carbohydrate content, can be important factors in regulating the peripheral metabolism of thyroid hormones.

    A post cycle crash is inevitable; this is the time when your diet really matters.

    So how do I cycle this stuff?

    T3/Clen/Anavar Cycle

    Anavar is the single best steroid to stack with T3. Its anti catabolic properties are unmatched and it will not shut you down. There's nothing like simultaneous sex hormone and thyroid hormone shutdown; I bet it feels great. Primobolan at 200mg a week would be a good substitute since it doesn't shut you down. Dbol at 10-15mg taken in the morning can also be used but Arimidex must be included with the Dbol. T3 increases the amount of beta-3-adregenic receptors (by 500%!) in white adipose tissue, i.e. the fat that covers muscle. Since clen exerts most of its effect on the same receptors; the combination with T3 would yield quite a strong synergistic effect. T3/Clen may be too much for the heart in some people.

    T3:

    12.5mcg for 5-7 days (optional but recommended)

    37.5mcg for 5 days
    75mcg for 15 days
    50mcg for 5 days
    37.5mcg for 5 days
    25mcg for 5 days
    12.5 mcg for 5 days
    6.25mcg for 5-7 days

    Clen:

    30 days: 60-120mcg ED. Use clen from the first 37.5mcg dose to the last 25mcg dose. Ketotifen will make you more sensitive to clenbuterol so doses should be adjust accordingly.

    Ketotifen:

    Stacked with Clenbuterol, 2mg ED. This drug may not be an option for some people since it can make them extremely hungry. If this is the case, Clen should be used 2 weeks on 2 weeks off.

    Anavar:

    Oxandrin;

    15mg ED with 37.5mcg of T3,
    25mg ED with 75mcg of T3,
    20mg ED with 50mcg of T3.


    Here's a more sensitive approach that can be used between cycles since it doesn't include AS:

    BigAndy69's T3 Cycle:

    The cycle can actually be used to add muscle mass or drop body fat depending on caloric intake. For gaining muscle mass, the Yohimbine and Anastrozole are not necessary.

    W1-W4:

    T3: 12.5mg ED
    Clen: 60-100mcg ED
    Ketotifen: 2mg ED
    Anastrozole: 0.5mg ED
    Yohimbine: 10-15mg ED (maybe too much to handle in some)

    Carb/Pro/Fat:

    20-30/50-60/20

    ALA: 1500mg ED
    Taurine: 3g ED

    W5:

    T3: 6.25mg ED

    L-Tyrosine: 1-2g ED
    ALA: 2500mg ED
    Taurine: 3g ED

    Carb/Pro/Fat:

    50-60/20-30/20

    (High Intensity Cardio)

    W6:

    ALA: 1500mg ED

    Carb/Pro/Fat:

    40/40/20

    (High Intensity Cardio)


    BigAndy69's T3 Post Cycle Therapy (4-6 weeks):

    Initial 3 day carb up:

    Carbs: 1.75g X BW
    Protein: 0.75g X BW
    Fat: 0.25g X BW

    Supplements:

    L-Tyrosine: 1-3g ED
    ALA: 1500mg ED
    Flaxseed oil + Fish oil: 20g total ED

    Diet: >50% Carbs/ 30% Protein/ <20% Fat, calories at maintenance (+ or - 12 X BW)

    High intensity cardio: 75-80% of Max Heart Rate; 15-20 min 3-4 times a week.

    No Steroids, Ephedrine, Clen, T2, DNP, or anything that has an effect on metabolism. Moderate doses of caffeine can be used before cardio.


    Anything Else I should know?

    T3 should be taken on an empty stomach, in the morning. If more than 50mcg is being taken, then it should be split through the day.

    BigAndy69


    References:


    N Engl J Med 1975 Oct 2;293(14):681-4
    Recovery of pituitary thyrotropic function after withdrawal of prolonged thyroid-suppression therapy.
    Vagenakis AG, Braverman LE, Azizi F, Portinay GI, Ingbar SH.

    Dietary-induced alterations in thyroid hormone metabolism during overnutrition.
    Danforth E Jr, Horton ES, O'Connell M, Sims EA, Burger AG, Ingbar SH, Braverman L, Vagenakis AG.

    A paradigm of experimentally induced mild hyperthyroidism: effects on nitrogen balance, body composition, and energy expenditure in healthy young men.

    J Clin Endocrinol Metab 1997 Mar;82(3):765-70 (ISSN: 0021-972X)
    Lovejoy JC; Smith SR; Bray GA; De Lany JP; Rood JC; Gouvier D; Windhauser M; Ryan DH; Macchiavelli R; Tulley R
    Pennington Biomedical Research Center, Louisiana State University, Baton Rouge 70808, USA. [email protected].

    Metabolism 1981 Aug;30(8):783-91
    Whole body leucine and lysine metabolism studied with [1-13C]leucine and [alpha-15N]lysine: response in healthy young men given excess energy intake.
    Motil KJ, Bier DM, Matthews DE, Burke JF, Young VR.

    Rubio A, et al. "Thyroid hormone and norepinephrine signaling in brown adipose tissue. II: Differential effects of thyroid hormone on beta 3-adrenergic receptors in brown and white adipose tissue." Endocrinology 1995 Aug;136(8):3277-84
    Last edited by Presser; 06-11-2016 at 04:24 PM.


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    Bumping for spring and current thread questions in main forum concerning this!


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    bump good read
     

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    Low dose T3 on cycle (6-12mcg)ed = increase nutrient uptake? read it some place but having trouble finding more info on this, any body have any experience?
    Dim ME tha BOLD (Gimme the BOLD!!)

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    Quote Originally Posted by DEMIGOD View Post
    Low dose T3 on cycle (6-12mcg)ed = increase nutrient uptake? read it some place but having trouble finding more info on this, any body have any experience?
    no, but thats a great article or study to contribute to the musclechemistry community here if we can find and post that information on t3 increasing nutrient uptake at a dosage of 6-12micrograms daily.

    i will go see if i can add to this, I know its a couple year old thread here but great info none the less


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    cytomel, t3 and t4 THYROID HORMONEs

    The thyroid is a gland that wraps itself around the larynx just behind the trachea. It produces two active hormones known as triiodothyronine and thyroxine. Triiodothyronine and thyroxine are each composed of two amino acids of tyrosine and only differ by the amount of bound iodine. Triiodothyronine has three iodides bound to it while thyroxine has four. This is why they are called T3 and T4.

    T3 and T4 are released by the thyroid into the blood where they bind to specialized proteins that carry them to other parts of the body. for the most part, both hormones have identical functions but must be released from their binding proteins to be active. T3 is the more powerful of these twins; although it is present in amounts that are 30-60 times lower than T4. However, many cells are capable of removing one of the iodides from T4 and converting it to the more active T3.

    Once these hormones reach the muscles, they are released from their binding proteins and are carried inside the cells by receptors on the cell membrane. Inside the cell, there are two targets where T3 can exert its effect. One is the nucleus where it can bind to the genes and increase protein synthesis. The other is the mitochondria, which are the power factories that burn calories in the presence of oxygen to produce adenosine triphosphate (ATh). It is believed that T3 can increase the mitochondria's ability to burn calories and thus raise the basal metabolic rate (BMR). In addition, T3 will also cause an increase in the number and size of the mitochondria, which will further serve to increase BMR.

    t3 and t4 mechanism of action

    The effects of the thyroid hormones are many and can be most advantageous to the bodybuilder. Every bodybuilder knows that muscles look their best when you're ripped and there's no excess bodyfat to obscure the striations. This is where T3 really excels by helping a person burn away those puffy little fat cells. T3 increases the BMR in nearly every cell of the body, especially the muscles, It does so by causing the fat cells to release free fatty acids into the bloodstream where they are taken up by the tissues. Here they are burned by the hyperactive mitochondria to make the ATP that drives muscle contractions. This energy can then be used to support muscle contractions for exercise and protein synthesis for growth. Another benefit is that although T3 increases the level of free fatty acids in the blood, it lowers cholesterol and triglyceride levels.

    T3 is so effective at cranking up the metabolic fires and using fat to feed these fires that it can actually increase the BMR by 60- 100%. So if one can increase their T3 levels just a little it can have a profound effect on metabolism. Since one of the bodybuilder's prime concerns is keeping off bodyfat, T3 easily earns its title of master of metabolism for bumping up the BMR. even if it did nothing else at all.

    But T3 does more than function as a terminator for fat cells. Another site of action for T3 is the muscles, where slight increases in this hormone causes the muscles to react to increased resistance with greater vigor. It accomplishes this by increasing the number of sarcoplasmic reticulum, which control contractions, and the energy- producing mitochondria that provide the muscle with the energy to do work. T3 has also been shown to cause an increase in the muscle's production of myosin, which is one of the major contractile proteins in muscle. Much of this accomplished by T3's ability to activate genes and cause an increase in protein synthesis in the muscles.

    Nothing escapes the influence of T3, since it can also stimulate almost all aspects of carbohydrate metabolism. It can increase the absorption of glucose by the intestinal tract, increase the uptake of glucose by the cells, and increase glucolysis. In glycolysis, the excess glucose that is not needed for glycogen production is broken down and burned by the mitochondria to produce even more ATP.

    T3 also has the ability to influence other hormones. Because it can cause blood sugar levels to rise, this causes a release of insulin from the pancreas to deal with the flood of glucose. As we have seen in the previous parts of this series, rapid rises in insulin can lead to hypoglycemia, which induces the production and release of growth hormone. T3 also causes a greater release of lactate and a lowering of blood pH. Acidic blood conditions are another mechanism by which growth hormone is induced. The induced growth hormone in turn causes the synthesis of insulin-like growth factor several hours later. All these hormones working in concert can produce an anabolic environment that will give maximum support to muscle growth and repair after an intense workout.

    In addition to providing a rich anabolic setting for muscle growth, T3 has no tolerance for catabolic conditions. It acts directly on the liver to increase the rate of destruction of the adrenal glucocorticoids, such as cortisol, which are responsible for protein breakdown. This decrease in cortisol will allow for greater recovery and uninterrupted muscle growth.

    There are other effects of T3 that are worth mentioning in brief. The increased BMR causes the muscles to demand increased oxygen to keep up with the greater burning of fats and energy production. To do this, T3 increases the respiratory capacity by increasing the depth of respiration and allows better oxygen utilization by the lungs. It also increases the strength of the heartbeat, increases blood volume and elevates blood pressure in the arteries. It also causes the vessels to expand and lower blood pressure. This decrease of blood pressure in the vessels offsets the rise in the arteries, so overall blood pressure remains unchanged. The result is greater amounts of oxygen-rich blood available to bathe the muscles with oxygen and nutrients and carry away waste metabolic by products.

    thyroid stimulating hormone cytomel

    As mentioned earlier, thyroid hormones have a normal range that varies from high to low. So to get the full benefits of T3, we must provide the body with conditions that will keep this hormone in the high range of production. One way to do this is through exercise. Most studies agree that intense exercise causes a rise in serum T3 and T4 levels. Repeated bouts of exercise cause an increased turnover of thyroid hormones. This means that the destructive process for thyroid hormones increases and signals the pituitary gland to release more thyroid stimulating hormone (TSR). The TSH causes the thyroid to produce more thyroid hormones.

    This is somewhat of a slingshot effect, where the initial exercise pulls the thyroid hormones to the low end of the normal range. The body responds by cranking up the production of T3 and T4 to get levels back up to the normal range. This panic response by the body to the fall in thyroid hormones will result in their overproduction. and as the levels rise, they shoot past the midpoint and rise to the upper normal range. The result is that a person rcmains slightly hyperthyroid for a while until the turnover slows and thyroid levels fall back to the normal midrange.

    As mentioned, intensity is necessary to get this process rolling. Studies of people who switched from a sedimentary lifestyle to one of moderate exercise showed no increase in their thyroid hormone levels. However, when the amount of exercise was doubled, there was a significant increase in thyroid hormone secretion. As we know there are two ways to increase the amount of exercise we perform-work longer or work harder. For bodybuilders the greatest advantage comes from working harder. or increasing the intensity of the workout.

    Another factor that affects thyroid function is nutrition. People who go on a calorie-restricted diet cause the body to lower its BMR to conserve energy, and this causes a decrease in thyroid hormone production. If a person increases their food intake, thy- old hormone production increases to turn up the BMR and burn the extra calories. When a person exercises intensely, two independent changes occur. They burn calories during exercise and they increase their production of thyroid hormone, which raises their BMR and burns still more calories. However, if this energy burned during exercise isn't replaced, the production of thyroid hormones will decrease.

    Also see that you get plenty of zinc in your diet. Zinc is thought to possibly play role in thyroid hormone metabolism and aid in the conversion of T4 to T3.

    That's why it's important for bodybuilders to supplement their diets to replace expended energy. Two of the best nutrients for increasing the production of T3 and T4 are protein and complex carbohydrates. When people were led a protein/carbohydrate diet that was either low or high in fat. only the low-fat diet elevated thyroid hormone levels. It seems that carbohydrates and protein can stimulate T3 and T4, but fat inhibits their release. That's why sports supplements are an important tool in bodybuilding. They are designed to be high in protein and carbs, while extremely low in fat. This makes them obvious choices for replacing energy used during exercise and inducing T3 and T4.

    T3 Enhances protein synthesis allowing you to build more muscle!

    Thyroid hormone loves muscle and hates fat. That's why it's a bodybuilder's best friend. Because muscles are the primary site of our body's BMR. T3 works to increase this lean mass so there will be increased BMR available to burn fat. To accomplish this, T3 virtually increases all aspects of protein synthesis in the muscles to allow growth to occur. It also increases the efficiency in which fat is burned. It can actually double the calories burned for each unit of work performed. That means twice the fat get burned while you train and grow. So as you can see, the thyroid hormones may well be one of bodybuilding's best kept secrets. And the good news is you don't have to travel to the distant ends of the earth like Indiana Jones to drink from this grail. Its benefits can always be summoned forth if one stimulates the muscles by using the principles and techniques of bodybuilding. while maintaining a proper diet that includes supplements. Do so. and the power of T3 will always be there for you.
    Last edited by Presser; 06-11-2016 at 04:34 PM.


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    Recovery of pituitary thyrotropic function after withdrawal of prolonged thyroid-suppression therapy.

    Vagenakis AG,*Braverman LE,*Azizi F,*Portinay GI,*Ingbar SH.

    Abstract

    The pattern of thyrotropin secretion was analyzed in seven euthyroid women, before and after withdrawal of long-term thyroid hormone, by serial measurements of thyroid 131l uptake, serum thyroxine, tri-iodothyronine, and thyrotropin concentrations, and the response to thyrotropin-releasing hormone. During exogenous hormone administration, 131l uptake was suppressed, and serum thyrotropin concentrations before and after administration of thyrotropin-releasing hormone were undetectable. After withdrawal of exogenous hormone, thyrotropin secretory function was transiently impaired, as indicated by undetectable basal thyrotropin concentrations together with absence of response to thyrotropin-releasing hormone, and subsequently by normal values of basal thyrotropin concentration and normal responses to releasing hormone while serum thyroxine and tri-iodothyronine concentrations were subnormal. Decreased thyrotropin reserve persisted for two to five weeks. Detectable values of serum thyrotropin (less than 1.2 muU per milliliter) and a normal 131l uptake usually occurred concurrently in two to three weeks. Serum thyroxine concentration returned to normal at least four weeks after hormone withdrawal.

    PMID:*808728*DOI:10.1056/NEJM197510022931402

    [PubMed - indexed for MEDLINE]



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    now in Lay terms ? lol
    Likes jimbosmith316 liked this post
     


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    T3 &amp; T4 with Steroid Cycle for Fatloss. T3, Clen, Anavar Cycle

    Bodybuilding

    T3 &amp; T4 with Steroid Cycle for Fatloss. T3, Clen, Anavar Cycle

    T3 &amp; T4 with Steroid Cycle for Fatloss. T3, Clen, Anavar Cycle

    T3 &amp; T4 with Steroid Cycle for Fatloss. T3, Clen, Anavar Cycle
    Quote Originally Posted by Presser View Post
    now in Lay terms ? lol
    From all I have read and people I have talked with 2-5 weeks and your thyroid gland will be back to normal no matter how long it has been shut down with T3 and T4 use. Lol

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    Modern bodybuilding is ritual, religion, sport, art, and science, awash in Western chemistry and mathematics. Defying nature, it surpasses it.

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