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  1. M

    Is this too long a cycle?

    i don't think genetics will greatly affect how you react to extended periods of shutdown. they will affect your reaction to the individual sides, but not "sides over time", if that makes sense. at your age you should primarily be worried about BPH(benign prostate hyperplasia) and high blood...
  2. M

    Any hockey fans?

    i'm from colorado, where we're almost as big on hockey as michigan, which is almost as big on hockey as canada. i've been to the hall of fame in t.o., and love the sport -- but i'm fuming angry at the players. how much money does a guy need to play a game for a living? :rolleyes: i will say...
  3. M

    New Members!!!!!!!!

    marble here; getbig's my home board. i'm another one of your biochemist dweebs who thinks he's a bodybuilder too. :D i came here mostly to discuss lr3igf-i, but there aren't many people left to discuss it with... i know the history of the board and am amazed it's still around, but similarly...
  4. M

    antibiotics & juice???

    you'll be safe. run the full course. avoid long-term antibiotic use because it will inhibit your body's protein synthesis. eat yoghurt only if you like it. :D details below. this depends on the type of antibiotic. most antibiotics work via inhibition of some aspect of bacterial protein...
  5. M

    LR3IGF-I + GH -- Synergistic?

    the feedback loop whereby igf-i acts on gh production at the pituitary is a strange one. apparently each cell has its own on/off switch, so it's either all or nothing, *but* the point at which this switch varies widely from cell to cell. http://mend.endojournals.org/cgi/content/full/15/9/1549...
  6. M

    lr3igf-i and your gut

    there's been a lot of rumination on whether lr3igf-i is able to cause the gh gut so fashionable amongst pros today. i believe the science can lead us to categorically conclude "no", with two exceptions: concurrent use of GH, and oral use. before we begin, note that rats are a terrible model...
  7. M

    IGF-1 R3, info for all

    ugh, where to begin... As a source of energy, IGF mobilizes fat for use as energy in adipose tissue. nope. this is a direct action of GH unmediated by IGF-I at all. IGF-I causes adipocyte hyperplasia if anything. IGF prevents insulin from transporting glucose across cell membranes. As a...
  8. M

    IGF-1 negative feedback loop

    i want to respond to your excellent questions in a new thread to aggregate peoples' experiences so we can all learn. you'll find my answers in the "LR3IGF-I " hGH -- Synergistic?" poll. for now: "The effects of GH one bone formation and organ growth are mediated by the endocrine action of...
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