SARM LGD-4033 (Ligandrol)

SARM LGD-4033 (Ligandrol)

I have used SARM LGD-4033 (Ligandrol) as well… Now 6 weeks @ 5mg to 8mg ED I put on 10 lbs and kept 7 lbs I didn’t use SERM 4 PCT tho. This stuff is like MK2866 Ostrine but 12x more anabolic & it made me hungry AF!

What is LGD-4033? *LGD-4033 is a selective androgen receptor modulator a novel non-steroidal, oral SARM that binds to AR with high affinity (Ki of ~1 nM) and selectivity, class of androgen receptor (AR) ligands that is tissue selective, developed to treat muscle wasting associated with cancer, acute and chronic illness and age-related muscle loss. LGD-4033 is expected to produce the therapeutic benefits of testosterone with improved safety, tolerability and patient acceptance due to tissue-selective mechanism of action and an oral route of administration.

How it works LGD-4033, a novel nonsteroidal, oral selective androgen receptor modulator, binds androgen receptora with high affinity and selectivity. It demonstrates anabolic activity in muscles, anti-resorptive and anabolic activity in bones and a robust selectivity for muscle and bone versus prostate and sebaceous glands. LGD-4033 has recently completed a Phase I Multiple Ascending Dose study in healthy volunteers this randomized, double-blind, placebo-controlled Phase I study established the safety and tolerability up to doses of 22*mg.

Usage LGD is still fairly new but the results have been very similar in studies and logs. LGD-4033 has undergone several recent studies and trials to find the best and safest way to use it. From these trials, the results have shown increases in lean body mass and decreases in body fat. There is also a significant increase in strength, well being as well as healing possibilities as well.

As a bulker SARM LGD-4033 (Ligandrol) has shown the most ability of any SARM to put on size that could be considered a bulk. This will, of course, be dependent upon the diet used. Users that have experienced more than 10lb. increases have had a significant increase in calorie intake. The possibility of this type of size is present with LGD use. A recommend dosage for this type of goal would be 5-10 mg day for 8 weeks.

Recomp agent SARM LGD-4033 (Ligandrol) seems to shine with this method. Many have seen an increase in lean body mass and a decrease in body fat. LGD seems to work the best with this method. Ran in conjunction with other SARMS will only increase the liklihood of a stronger recomp. Recommended doses for recomping would be 5-8 mg a day for 8 weeks.

As a Cutter LGD can be used to cut as well. It will shine moreso if ran in conjunction with SARMS S-4 and GW-501516. This would be similar to a SARMS triple stack that is normally ran with ostarine, except there is a possibility of more size being put on while cutting. A good dose for this method would be 3-5 mg a day for 8 weeks.

Side effects Through studies and logs, the side effects from LGD have so far shown to be minimal. The suppression that has shown has been dose dependent but there has been a decrease in total and free test as well as SHBG. The interesting findings shown have show NO significant decrease in LH or FSH. This is very encouraging to users as it shows that while suppressive, recovery will still not be near as long as with anabolics. It has shown to be non toxic and side effects have been mild to minimal. LGD has not shown increases in estradiol but as with anything, an anti aromatizer should be kept on hand. A full pct, as opposed to a mini pct with other SARMS, is recommended after a cycle of LGD. While it may not be quite as suppressive as anabolics, the suppression is much higher than other SARMS, thus, requiring a full PCT.

Summary fo LGD 4033 Effects similar to anabolics with size and strength Minimal Side Effects Excellent for recomping Healing properties Prevents muscle wasting Works well as a stand alone or stacked with other SARMS (May compete w/ MK2866 Ostrine thus may not be benefitial to stack with) – Great results in every aspect for different types of goals Half life of 24-36 hours

I’d stack it w/ IGF1 LR3 from or other growth peptides. I’d LOVE to use this along w/ GHRP-6 & IGF1 LR3 during bulk! GHRP-6 gives users MASSIVE inrease in appetite higher than EQ from users experience. I have never use GHRP-6 but I have used GHRP-2 and it makes u hungry w/in 10mins of applying it. Add IGF1 LR3 OMG I bet u’d explode w/ LBM!

Customer Reviews on SARM Ligandrol lgd 4033 can be found on MuscleChemistry Bodybuilding Forum.


  1. Ligandrol (LGD-4033)Ligandrol is a SARM discovered by Ligand Pharmaceuticalsand currently under licensed development by Viking THerapeutics.
    There has been a lot of research into the efficacy of SARMs,but very little published research to date on LGD-4033. Ligandrolhas exhibited desirable in vivo efficacy on skeletal muscle andbone measurements in animal models of disease. There is onlyone published study on the effects of LGD-4033 in humans, as wellas phase B1 clinical trial results.
    A 2010 phase1 clinical trial wasthe first study in humans of LGD-4033 and evaluated the safety,tolerability and oharmacokinetic profiles of the molecule in asingle escalating dose, double-blind, placebo-controlled study in 48healthy volunteers .In 2013, Bhasia et al. conducted a rigorous 3-week pacebocontrolledstudy of 76 healthy men (21-50 years),that looked at thesafety and tolerability of LGD-4033. During this study participantswere randomized to placebo,0,1.0,3 or 1mg LGD-4033 for 21 days.
    The study evaluated the safety, tolerability, pharmacokinetics andthe effects of ascending doses of LGD-4033 on lean body mass,muscle strength, stair climbing power and sex hormones .The sample size was still small and the study was not based onconsiderations of effect sizes, as the study’s primary aim was toestablish safety and tolerability, rather than efficacy. Similarly, the3-week study duration was not designed to demonstrate maximaleffects on muscle mass and strength. Therefore larger and longerstudies are needed to access the efficacy of LGD-4033.
    Furthermorethe study was supported by Ligand Pharmaceuticals, who developedLGD-4033.Ligandrol showed a dose-dependent suppression of totaltestosterone from baseline to 21 days, rather than an increase.Ligandrol did not result in fat loss in this study. It promotedmuscle growth, but the evidence is very early weak evidence atthis stage.
    There was an increase in lean body mass, that was doserelated.The mechanisms by which androgens increase musclemass remain incompletely understood. However, the increase instrength measured by stair climbing speed and power also showedimprovement, but not enough to be statistically significant. With alarger sample size and or longer study, it is possible that this effectmay be demonstrated. LGD-4033 displayed an immediate effecton hormones in the body from the time it was taken. The researchshowed gains in lean muscle mass within the 21 days of the study.Adverse effects were not noted. LGD-4033 displayed a prolongedelimination half- life of 24-36 hours. Upon discontinuation of LGD4033the hormone levels returned to baseline by day 56 . Thereis just not enough research to show the efficacy of Ligandrol at thisstage,despite it was safe and well tolerated at all doses administered.
    Article states to do a full pct after using LGD4033.
    I will be on 100 mg of test c weekly.
    What would you recommend for a pct, how much and how long?
Andarine s4, Ostarine mk 2866, Ligandrol lgd 4033, Cardarine GW501516, Stenabolic SR9009, IGF 1 Lr3, Aromatase Inhibitors,
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