Article: Reps Per Set for Optimal Growth

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Reps Per Set for Optimal Growth
Lyle McDonald

I’m going to throw out a weird hypothetical question that I want readers to consider before continuing with this article.

If you had to pick a single repetition range to train in for growth, what would it be?

That is, imagine some very strange situation where you could only train within a certain range (and let’s make that range something a little less vague then ‘Between 1-20 reps’ by limiting it to a 3 rep range) for the rest of your lifting career, what would it be?

I used to ask this of friends of mine in the field and, almost with exception, the answer was pretty much the same. This was true regardless of whether or not they had arrived at that value from experimentation and experience or just looking at the research.

I’m going to take a quick look at the research (including a bunch of seemingly disparate topics) to tell you what I’d pick.

What Makes Muscle Grow?
I asked a job supervisor that question once once; he was a smart-ass like me and told me “It needs lots of sunlight and water.” Close but not quite.
The mechanism of muscle growth has been under heavy scrutiny for years and a lot of theories and ideas have come and gone in terms of both the mechanism of growth as well as what stimulates it. Semi-amusingly, about 98% of the actual answer was known back in the 70’s.

In an exceptional paper (which I recommend the reading of to any nerds in the field) titled “Mechanism of work induced hypertrophy of skeletal muscle” a researcher named Goldspink pretty much laid it out concluding that:
It is suggested that increased tension development (either passive or active) is the critical event in initiating compensatory growth.

Basically, the development of high levels of tension within the muscle is the key factor in initiating the growth process. I’d note that there are also some elements of fatigue that may be contributing to what ‘turns on’ the growth response. Finally, I’d note that in order to keep stimulating growth beyond an acute training bout, there has to be an increase in tension. Basically, over time you have to add weight to the bar.

Which as another great scientist in the field (Ronnie Coleman) summed up thusly:

Everybody wants to be a bodybuilder, but nobody wants to lift no heavy-ass weights.

The simple fact is that, outside of heavy drug users (steroids having the capacity to stimulate growth without even training), the biggest bodybuilders are the strongest. They grow because they provide, over time, a progressive tension overload (of course there are more variables that go into this, total workload per workout, frequency of training and diet all interact here).

But as I have been pointing out for years and years and years, if you’re not adding weight to the bar over time, you’re simply not growing. You can focus on the feel and the pump and the squeeze all you want; if you’re using the same weights 6 months from now that you’re using today, you won’t be any bigger.

Which doesn’t mean that you have to add weight at every workout (the fallacy of HIT), simply that over time you have to be lifting more weight. But progression over time is a whole separate article.

Anyhow, the summary of this section is that a combination of tension overload (with a possible contributor of fatigue) within skeletal muscle fibers is what turns on the growth response. Just remember that, what stimulates growth is tension and fatigue (with tension playing a relatively larger role in terms of actual contractile growth).

Which brings us to the next question: what’s the best way to develop that combination of tension and fatigue within skeletal muscle (or a given fiber)?

A Quick Tangent into Some Neurophysiology
When you look at strength production, the body has essentially two methods to increase force output which are

1. Muscle fiber recruitment
2. Rate coding

Muscle fiber recruitment is exactly what it sounds like, how many of the fibers within a muscle are actually being recruited. Contrary to the exceptional silliness which is endlessly repeated in books and on the internet, most people can actually get pretty close to 100% fiber recruitment (it’s a little bit lower in the lower body but, in the triceps for example, people can get near 100% recruitment).

Rate coding referes to how quickly the body is sending electrical signals to that muscle. As rate coding goes up, the muscle fires harder.

Now, in the muscles we’re interested in from a sports or bodybuilding standpoint, the body will generally use recruitment to increase force production up to about 80-85% of maximum force output (in the lab, this is measured with Maximal Voluntary Isometric Contraction or MVIC, which is effectively 1 rep maximum weight). Beyond 80-85% of maximum, it uses rate coding.

I’d note for completenes that this isn’t true for some muscles in the body, notably stuff like the eye muscles and finger muscles. In those muscles, recruitment is used up to about 50% of MVIC and rate coding handles the rest. Which is a lot of why studies looking at the thumb muscles aren’t really relevant to most training applications. But I digress.

Anyhow, now we have the next part of the picture, the body will recruit more fibers up to about 80-85% of maximum; above that point, there is no further recruitment and force output is improved via rate coding.

I should note that even at lower intensities, as the individual goes to fatigue, eventually all muscle fibers will end up being recruited. But they won’t have been recruited until fairly late in the set (e.g. the last few repetitions).

Putting it Together
And this leads us to our answer to my original question. For most people, 80-85% of maximum is roughly 5-8 repetitions there is variance in this between individuals and perhaps muscle groups (for example, some people find that they can get 12-15 repetitions at 85% of maximum in some leg movements).

Now let’s put that together with my comments about tension and fatigue from the earlier in the article.

Imagine that you put 95% on the bar, which will let most people get about 2 reps. You wouldn’t increase fiber recruitment (remember, it maxes at 80-85%) but you would drastically decrease any fatigue because you would be getting a lot less reps per set (and most people couldn’t do many sets of 2 at 90% so their total volume per workout would be much lower).

Or say you wanted to do 15 repetitions which, for most is about 70% of maximum. If you take it to failure, you will in fact end up recruiting all muscle fibers; however many of them (and this especially holds for the highest threshold fibers, the ones with the potential for the most growth) won’t have been recruited until near the very end. So those highest threshold fibers won’t be exposed to high tension and fatigue for very long.

In contrast, imagine that you work in the 5-8 rep range with 80-85% of maximum. First and foremost you will get full muscle fiber recruitment from the first repetition. Secondly, you will maximize fatigue/metabolic work/volume within that range. Basically, that range of reps and intensities is the one that will give an optimal balance of tension/recruitment and fatigue/metabolic work.

And that’s the answer that repeatedly comes up among people in the field who aren’t clueless: 5-8 repetitions. If you had to pick a single rep range to work at to optimize the growth response, it would 5-8 reps per set.

Which isn’t to say that there aren’t valid and valuable reasons to work in other repetition ranges, mind you. But that wasn’t the original context of my weird hypothetical.

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Bad ass article bro, i grow a shit ton better at 6 reps then i do at 12 or 15 . I usually stay at 6 to 8 unless im trying to switch things up.
 
ok well i usualy use 2 Reps per set. For example on bench press I use 2 reps per set. 1 rep on one side of the bar and one rep on the other side of the bar so i can go to failure and in case i need them to lift the bar off my chest, so for me I use 2 reps per set,lmao

Now figure that thinking out,lol
 
I would have to respectfully disagree with the article. 5-8 reps is good, especially when focusing on strength, the lower end being mostly strength and placing much more focus on tendons and ligaments than the actual skeletal muscle. Given this fact, it would be impossible for 100% muscle fiber recruitment on the very first rep at 85% of max. Also muscle fiber type must be taken into consideration. There are two main types, slow twitch and fast twitch with many different variations in between. While fast twitch muscle fibers are easy to exhaust for hypertrophy, slow twitch and other muscle fibers that are combinations of the two need more work to exhaust to reach hypertrophy levels. Other variables which are taken for granted in this article is that nutrition is adequate. As we all know, hypertrophy is micro-tears that occur in the muscle fiber from stress, and then given adequate nutrition and rest, the muscle fiber heals and then overcompensates to be better able to handle the load for the next time. So I still believe that a 6-12 rep range is still optimum for hypertrophy purposes, probably more like 10-20 for lower body which is comprised of more slow twitch fibers, so that all muscle fiber types are stimulated, and the all important pump crams lactic acid and nutrient rich blood to the working muscles. So hypothetically, 5-8 reps is too cookie cutter of a forumula, and narrowing it down to within a 3 rep range is not practical in the real world. But that's just my .02 cents.
 
I would have to respectfully disagree with the article. 5-8 reps is good, especially when focusing on strength, the lower end being mostly strength and placing much more focus on tendons and ligaments than the actual skeletal muscle. Given this fact, it would be impossible for 100% muscle fiber recruitment on the very first rep at 85% of max. Also muscle fiber type must be taken into consideration. There are two main types, slow twitch and fast twitch with many different variations in between. While fast twitch muscle fibers are easy to exhaust for hypertrophy, slow twitch and other muscle fibers that are combinations of the two need more work to exhaust to reach hypertrophy levels. Other variables which are taken for granted in this article is that nutrition is adequate. As we all know, hypertrophy is micro-tears that occur in the muscle fiber from stress, and then given adequate nutrition and rest, the muscle fiber heals and then overcompensates to be better able to handle the load for the next time. So I still believe that a 6-12 rep range is still optimum for hypertrophy purposes, probably more like 10-20 for lower body which is comprised of more slow twitch fibers, so that all muscle fiber types are stimulated, and the all important pump crams lactic acid and nutrient rich blood to the working muscles. So hypothetically, 5-8 reps is too cookie cutter of a forumula, and narrowing it down to within a 3 rep range is not practical in the real world. But that's just my .02 cents.

I don't think he was talking about getting 100% recruitment at the first rep but 100% by the end of the set. I think the important part to remember is the 80-85% of max part of the equation. He also mentioned there will be some variation since some people can do 12-15 reps at 80-85% of max. I think the suggestion is valid to start with 5-8 reps at 80-85% of max. If you find you can do more than that, then you should adjust your workout accordingly. It all comes down to what works for you really, but the article gives a good jumping off point.
 
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