DecaDent*
New member
Anyone using Proscar or Propecia (both are finasteride) to block DHT (reduces test to DHT conversion to lower risk of baldness and prostate problems associated with elevated DHT levels) might want to consider Avodart(dutasteride) instead.
It is a more potent DHT blocker.
Heres some info:
Avodart (dutasteride) capsules
Manufacturer: GlaxoSmithKline
Dosing:Avodart recommended dosing is 1 capsule (0.5 mg) taken orally once daily. Avodart may be taken with or without food.
Clinical Summary: Dutasteride is a synthetic 4-azasteroid compound that is a selective inhibitor of both the type 1 and type 2 isoforms of steroid 5alpha-reductase, an intracellular enzyme that converts testosterone to 5alpha-dihydrotestosterone.
Adverse Effects: The most common adverse events were related to reproductive system effects (impotence, decreased libido, ejaculation disorder, and gynecomastia).
Pharmacokinetics: Cmax of dutasteride occurs within 2-3 hours after administration. Dutasteride is highly bound to plasma albumin (99.0%) and alpha-1 acid glycoprotein (96.6%). Dutasteride is metabolized by the CYP3A4 isoenzyme to 2 minor monohydroxylated metabolites. The terminal elimination half-life is approximately 5 weeks at steady state; serum concentrations are detectable for up to 4-6 months after discontinuation of therapy.
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It is a more potent DHT blocker.
Heres some info:
Avodart (dutasteride) capsules
Manufacturer: GlaxoSmithKline
Dosing:Avodart recommended dosing is 1 capsule (0.5 mg) taken orally once daily. Avodart may be taken with or without food.
Clinical Summary: Dutasteride is a synthetic 4-azasteroid compound that is a selective inhibitor of both the type 1 and type 2 isoforms of steroid 5alpha-reductase, an intracellular enzyme that converts testosterone to 5alpha-dihydrotestosterone.
Adverse Effects: The most common adverse events were related to reproductive system effects (impotence, decreased libido, ejaculation disorder, and gynecomastia).
Pharmacokinetics: Cmax of dutasteride occurs within 2-3 hours after administration. Dutasteride is highly bound to plasma albumin (99.0%) and alpha-1 acid glycoprotein (96.6%). Dutasteride is metabolized by the CYP3A4 isoenzyme to 2 minor monohydroxylated metabolites. The terminal elimination half-life is approximately 5 weeks at steady state; serum concentrations are detectable for up to 4-6 months after discontinuation of therapy.
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