jumping on T3 at higher doses makes me feel like total shit. Using the same logic as you Al (I see no reason to taper up, blah, blah), I jumped up to 50mcg a day and by the end of the 1st week, I had headaches, lost appetite, sleeplessness, and a general shitty feel (oh and I was sweating at night so fucking bad). Despite feeling like shit, I stayed with it for nearly 2 more weeks! The T3 experts kept telling me it would pass, well it didn't. I will never do that again.
I don't know if its an intolerance to higher dose T3 (I doubt it), or the fact that I slammed my TSH levels up that made me feel so rotten. But what I do know, is that I plan to ramp up slow next time to see how I feel. My plan is 12.5mcg for 1-2 weeks, then step it up to 25mcg for a week or two, etc...
DrG