Ok the pain isnt that bad once you get going. After the first week of pain your body seems to get used to it and the shots are nearly as painful. As far as the knots go, inject the solution slowly, rub for a couple minutes after inject, finally rub some tiger balm on the general area of injection. Knot free injects. AT the very least i think everyone should at least try it. As with everything, not everyone is going to see the same results.