Myostatin (MyoGro & GASP-1)

Has anyone else tried the myostatin inhibitors, GASP-1 or MyoGro?

I put on 10% mass/ week with this stuff. I can't use Roids cuz I lift professionally for the military. My stomach has got that 8-pack look finally too.

A buddy of mine wrestles at Ohio State and has put on a solid 20# of muscle in 3 months time. The dude was so fucking ripped it made me jealous.

Another buddy of mine cheers at West Georgia. He gained 8# of mass in less than a month.



I was wondering if anyone has tried GASP-1 or MyoGro, and how can we get a 3 month supply?

Here's the myostatin study that got me interested:


"Hill JJ, Qiu Y, Hewick RM, Wolfman NM. Related Articles, Links
Regulation of myostatin in vivo by growth and differentiation factor-associated serum protein-1: a novel protein with protease inhibitor and follistatin domains.
Mol Endocrinol. 2003 Jun;17(6):1144-54. Epub 2003 Feb 20.
PMID: 12595574

Myostatin, a member of the TGFbeta superfamily, is a potent and specific negative regulator of skeletal muscle mass. In serum, myostatin circulates as part of a latent complex containing myostatin propeptide and/or follistatin-related gene (FLRG). Here, we report the identification of an additional protein associated with endogenous myostatin in normal mouse and human serum, discovered by affinity purification and mass spectrometry. This protein, which we have named growth and differentiation factor-associated serum protein-1 (GASP-1), contains multiple domains associated with protease-inhibitory proteins, including a whey acidic protein domain, a Kazal domain, two Kunitz domains, and a netrin domain. GASP-1 also contains a domain homologous to the 10-cysteine repeat found in follistatin, a protein that binds and inhibits activin, another member of the TGFbeta superfamily. We have cloned mouse GASP-1 and shown that it inhibits the biological activity of mature myostatin, but not activin, in a luciferase reporter gene assay. Surprisingly, recombinant GASP-1 binds directly not only to mature myostatin, but also to the myostatin propeptide. Thus, GASP-1 represents a novel class of inhibitory TGFbeta binding proteins."

Cheers

Ryan

hmm don't know we are not source board.
That last I heard it was still in testing and lots of "grey areas" as far as long-term effects on humans.

There's a post around here somewhere I wil try to dig it up.

here it is.
http://board1.mantisforums.com/upload/showthread.php?s=&threadid=23450&highlight=myostatin

who's in the pic if I may ask?

guys read up my post in the other Myostatin thread.

I did sounds interesting.

MarineJock, couple things maybe you can clarify for me:
You put on 10% mass a week using it?? What does that mean? If your LBM was 200lbs. you put on 20lbs in a week? Do you mean 10% more mass then you were previously gaining?

Second, if you've already used it, why are you looking for a source?

Third of all, why are you looking for a source here when you started a thread on it on Silo's board? ( the only thread I might add) That was a month and a half ago on their board and a couople weeks on this one. Is your crotch in my face? Cause I smell something fishy...