tylenol is bad

i read that tylenol, advil, ibuprofen, all that, blocks your bodys ability to absorb protien in your muscles. they called it no pain no gain. if anyone can post any info about this please do, im curious about this and would like to know more.

To some degree it inhibits protien synthesis (hope thats good english).

Sincerely,

HL

Tylenol (acetaminophen) is just plain bad for you period. It is hard for the liver to take and it has been known to cause liver failure in high doses.

Quite a few people (granted they were booze hounds) or already had some sort of liver function impairment, have died from taking tylenol after a severe night of drinking.

Just like all of the other "supplements" that we take it has to be broken down by the liver. My doctor has personally warned me against acetaminophen. If you are concerned about liver health DO NOT TAKE THE STUFF!!

Personally I use aspirin, motrin. And what the heck if I'm gonna screw up my liver I go for the HYDRO! But seriously because of what I am doing it really is best to stay as chemical free as possible (but still attain our goals) I try to cut out everything that doesn't help me with getting bigger, stronger, faster....

Okay, this is an older study that I found. I know there are others that reflect the similar results.


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From the June 2001 issue of Muscle Media, "Research Update" by David Kennedy.

I interject my commentary to make it easier for the bros here that are not science buffs

Q: "Will using common over-the-counter analgesics like ibuprofen and acetaminophen negetively affect muscle growth?"

A:"Dr. Todd A Trappe and collegues from the University of Arkansas for Medical Sciences and the University of California, Berkeley, examined the effect of ibuprofen and acetaminophen on muscle protein metabolism following high-intensity resistance exercise. The researchers randomly assigned 24 males to one of three groups that received either the maximal OTC dose of ibuprofen (1200mg/day), acetaminophen (4000mg/day) or a placebo following 10 to 14 sets of 10 heavy eccentric repetitions on a leg-extension machine..."

So, some bros were told to bust their ass doing high-volume negatives on leg extensons and then take some pain killers or a placebo....sounds good.

"....Results showed that post-exercise muscle protein synthesis increaesd by an average of 76% in the placebo group..."

"....but was, disturbingly, UNCHANGED, in the groups taking acetaminophen or ibuprofen...."

AWW CRAP!!....no change in protein synthesis...in other words, the NSAIDS "STOPPED MUSCLE GROWTH" ....that can't be good

"...These results suggest that both ibuprofen and acetaminophen suppress skeletal muscle protein synthesis following eccentric exercise ... and may work through a common mechanism to influence protein metabolism in skeletal muscle."

In other words...it keeps you from growing, AND could use muscle proteins for energy (not good at all)....

So do yourself (and your muscles) a favor and kick the Tylenol and the Advil to the curb.

Hope this helps some.

Man, that's a little disturbing to read. I had heard that NSAIDS can inhibit your recovery to some degree, but for the study to show that it was completely blocked...wow. I guess I'll have to get used to really feeling the pain.

Did they say what the actual study was? I'd like to research that a little.

This is the study that is always quoted when talking about NSAIDS effect on muscle building. Pay attention to the dosage of IBU - 1.2g - not far off from the doses some are recommending.
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Am J Physiol Endocrinol Metab 2002 Mar;282(3):E551-6

Effect of ibuprofen and acetaminophen on postexercise muscle protein synthesis.

Trappe TA, White F, Lambert CP, Cesar D, Hellerstein M, Evans WJ.

We examined the effect of two commonly consumed over-the-counter analgesics, ibuprofen and acetaminophen, on muscle protein synthesis and soreness after high-intensity eccentric resistance exercise. Twenty-four males (25 +/- 3 yr, 180 +/- 6 cm, 81 +/- 6 kg, and 17 +/- 8% body fat) were assigned to one of three groups that received either the maximal over-the-counter dose of ibuprofen (IBU; 1,200 mg/day), acetaminophen (ACET; 4,000 mg/day), or a placebo (PLA) after 10-14 sets of 10 eccentric repetitions at 120% of concentric one-repetition maximum with the knee extensors. Postexercise (24 h) skeletal muscle fractional synthesis rate (FSR) was increased 76 +/- 19% (P < 0.05) in PLA (0.058 +/- 0.012%/h) and was unchanged (P > 0.05) in IBU (35 +/- 21%; 0.021 +/- 0.014%/h) and ACET (22 +/- 23%; 0.010 +/- 0.019%/h). Neither drug had any influence on whole body protein breakdown, as measured by rate of phenylalanine appearance, on serum creatine kinase, or on rating of perceived muscle soreness compared with PLA. These results suggest that over-the-counter doses of both ibuprofen and acetaminophen suppress the protein synthesis response in skeletal muscle after eccentric resistance exercise. Thus these two analgesics may work through a common mechanism to influence protein metabolism in skeletal muscle.

VIOXX

what about vioxx???

Can't go wrong with good Aspirin

fulforb said:

Can't go wrong with good Aspirin

Click to expand...

uhhhh....ulcers man. ulcers!