No big deal Tony! I always shot my IGF in the evening right before my workouts. My GH shots were first thing when I woke up, and in mid afternoon, so the IGF would be about 4 hours after my GH shot. I never experienced any hypo or anything like that. I'm not sure if there would be any concerns with shooting IGF and GH at the same time cause I've never done it. I wouldn't think that it would be a big deal though. As for injecting IGF, its the major consensus that its better injected in the evening so that you don't have to suffer through the lethargy that it brings during the day if you shoot in the morning. Also, while on GH you will be a little more sluggish than usual, so you don't want to amplify that, or else you'll be sleeping all the time. Sure you grow when you sleep, but you wouldn't be motivated to do anything but that. Let us know what you decide and how it goes.